N-((E)-But-2-enyl)-N-phenyl-hydrazine | 189179-84-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-((E)-But-2-enyl)-N-phenyl-hydrazine
• 英文别名: 1-[(E)-but-2-enyl]-1-phenylhydrazine
• CAS: 189179-84-8
• 化学式: C₁₀H₁₄N₂
• 分子量: 162.235
• InChiKey: FHJWLJFSBUSOAL-NSCUHMNNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.94
• 重原子数：
  12.0
• 可旋转键数：
  3.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  29.26
• 氢给体数：
  1.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  N-((E)-But-2-enyl)-N-phenyl-hydrazine 在 ammonium peroxydisulfate 、 三氟甲磺酸 、 二苯基二硒醚 作用下， 以 乙腈 为溶剂， 以76%的产率得到3-甲基-1-苯基吡唑
  参考文献：
  名称：

  Phenylselenenyl sulfate induced cyclization of allylhydrazines. Synthesis of pyrazole derivatives

  摘要：

  Allylhydrazines react with phenylselenenyl sulfate, produced by diphenyl diselenide and ammonium persulfate in the presence of trifluoromethanesulfonic acid, to afford phenylseleno substituted pyrazolidines. Under the reaction conditions employed, these suffer dehydrogenation and oxidative deselenenylation to eventually give pyrazole derivatives. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4020(97)00116-6
• 作为产物：
  描述：

  苯肼,盐酸盐 、 alkaline earth salt of/the/ methylsulfuric acid 在 potassium carbonate 作用下， 以 乙醇 为溶剂， 反应 12.0h， 生成 N-((E)-But-2-enyl)-N-phenyl-hydrazine
  参考文献：
  名称：

  Phenylselenenyl sulfate induced cyclization of allylhydrazines. Synthesis of pyrazole derivatives

  摘要：

  Allylhydrazines react with phenylselenenyl sulfate, produced by diphenyl diselenide and ammonium persulfate in the presence of trifluoromethanesulfonic acid, to afford phenylseleno substituted pyrazolidines. Under the reaction conditions employed, these suffer dehydrogenation and oxidative deselenenylation to eventually give pyrazole derivatives. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4020(97)00116-6

文献信息

• Phenylselenenyl sulfate induced cyclization of allylhydrazines. Synthesis of pyrazole derivatives
  作者：Marcello Tiecco、Lorenzo Testaferri、Francesca Marini、Luana Bagnoli、Claudio Santi、Andrea Temperini

  DOI：10.1016/s0040-4020(97)00116-6

  日期：1997.3

  Allylhydrazines react with phenylselenenyl sulfate, produced by diphenyl diselenide and ammonium persulfate in the presence of trifluoromethanesulfonic acid, to afford phenylseleno substituted pyrazolidines. Under the reaction conditions employed, these suffer dehydrogenation and oxidative deselenenylation to eventually give pyrazole derivatives. (C) 1997 Elsevier Science Ltd.