2,2'-bipyrimidine | 1452840-05-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 2,2'-bipyrimidine
• 英文别名: bpym；2-Pyrazin-2-ylpyrimidine
• CAS: 1452840-05-9
• 化学式: C₈H₆N₄
• 分子量: 158.162
• InChiKey: BCGJBDXCTCRWQO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  51.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  copper(II) nitrate trihydrate 、 2,2'-bipyrimidine 、 水 、 三氰基甲烷化钾 以 乙醇 、 水 为溶剂， 以27%的产率得到Cu4(2,2'-bipyrimidine)5(tricyanomethanide)8*2H2O
  参考文献：
  名称：

  Syntheses, structures and magnetic properties of two copper(II) tricyanomethanide complexes with 2,2′-bipyrimidine as bridging ligands

  摘要：

  Two copper(II) tricyanomethanide (tcm) complexes with 2,2'-bipyrimidine (bpym) as co-ligands Cu-1(bpym)(5)(tcm)(8) center dot 2H(2)O (1) and [Cu-2(bpym)(2)(tcm)(4) center dot H2O](n) (2) have been synthesized, and structurally and magnetically characterized. Compound 1 displays a tetranuclear structure, in which each middle copper(II) atom is coordinated by two bridging bpym molecules and two terminal tcm ligands to form a tetragonal bipyramidal geometry, while each side copper(II) atom is surrounded by one bridging bpym, one terminal bpym, one terminal bonded tcm and one terminal weakly coordinated tcm ligands to give a square bipyramidal geometry. In 1 the four neighbouring copper(II) atoms are joined to each other by the bpym molecules, which leads to the formation of a tetranuclear structure. Compound 2 features an infinite chain structure, in which two slightly different chains exist. In each chain the copper(II) atom is bonded to two bridging bpym molecules and two terminal tcm ligands to form a tetragonal bipyramidal geometry, the adjacent copper(II) atoms are linked each other by the bpym ligands to define an infinite chain structure. In 2 the distances between two neighbouring copper(II) atoms in one chain are different. Moreover these distances in one chain are also different from those of the other chain. Magnetic susceptibility measurements for the two complexes in the temperature range 2-300 K reveal the occurrence of significant antiferromagnetic interactions for 1 (J(1) = -20.42 cm (1), J(2) = -5.29 cm (1) and g = 2.22) and 2 (T > 50 K, theta = 20.00 K, C = 0.86 cm(3) mol (1) K), respectively. (C) 2008 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.ica.2008.08.017

文献信息

• [EN] HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRAZINE DERIVATIVES<br/>[FR] DÉRIVÉS DE PYRIDYLE-/PYRIMIDYLE-PYRAZINE À ACTIVITÉ HERBICIDE
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：WO2019057723A1

  公开（公告）日：2019-03-28

  The present invention relates to herbicidally active pyridyl-/pyrimidyl-pyrazine derivatives, as well as to processes and intermediates used for the preparation of such derivatives. The invention further extends to herbicidal compositions comprising such derivatives, as well as to the use of such compounds and compositions in controlling undesirable plant growth: in particular the use in controlling weeds, in crops of useful plants.

  本发明涉及具有除草活性的吡啶基/嘧啶基-吡嗪衍生物，以及用于制备这些衍生物的过程和中间体。该发明进一步涉及包括这些衍生物的除草组合物，以及利用这些化合物和组合物来控制不良植物生长的用途：特别是在控制杂草方面，在有用植物的作物中的使用。
• [EN] PYRAZINE-4-CARBAMATE OR -UREA DERIVATIVES AS HERBICIDES<br/>[FR] DÉRIVÉS DE PYRAZINE-4-CARBAMATE OU D'URÉE UTILISÉS EN TANT QU'HERBICIDES
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：WO2019057725A1

  公开（公告）日：2019-03-28

  The present invention relates to herbicidally active pyridyl-/pyrimidyl-pyrazine derivatives, as well as to processes and intermediates used for the preparation of such derivatives. The invention further extends to herbicidal compositions comprising such derivatives, as well as to the use of such compounds and compositions in controlling undesirable plant growth: in particular the use in controlling weeds, in crops of useful plants.

  本发明涉及具有除草活性的吡啶基/嘧啶基-吡嗪衍生物，以及用于制备这种衍生物的工艺和中间体。该发明进一步涉及包含这种衍生物的除草剂组合物，以及利用这些化合物和组合物控制不良植物生长的用途：特别是在有用植物作物中控制杂草的用途。
• [EN] PYRAZINE-4CARBAMATE OR -UREA DERIVATIVES AS HERBICIDES<br/>[FR] DÉRIVÉS DE PYRAZINE-4CARBAMATE OU D'URÉE UTILISÉS EN TANT QU'HERBICIDES
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：WO2019057724A1

  公开（公告）日：2019-03-28

  The present invention relates to herbicidally active pyridyl-/pyrimidyl-pyrazine derivatives, as well as to processes and intermediates used for the preparation of such derivatives. The invention further extends to herbicidal compositions comprising such derivatives, as well as to the use of such compounds and compositions in controlling undesirable plant growth: in particular the use in controlling weeds, in crops of useful plants.

  本发明涉及具有除草活性的吡啶基/嘧啶基-吡嗪衍生物，以及用于制备这些衍生物的过程和中间体。该发明还涉及包含这些衍生物的除草剂组合物，以及在控制不良植物生长方面使用这些化合物和组合物，特别是在作物中控制杂草的使用。
• Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade
  申请人：Pharmacia Corporation

  公开号：US20040102448A1

  公开（公告）日：2004-05-27

  The invention relates to substituted polycyclic aryl and heteroaryl pyrazinone compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of dirombotic conditions including coronary artery and cerebrovascular diseases.

  本发明涉及用作凝血级联中丝氨酸蛋白酶抑制剂的取代多环芳基和杂环芳基吡嗪酮化合物，以及用于治疗和预防包括冠状动脉和脑血管疾病在内的各种血栓病症的化合物、组合物和抗凝治疗方法。
• Herbicidally active pyridyl-/pyrimidyl-pyrazine derivatives
  申请人：Syngenta Participations AG

  公开号：US11229205B2

  公开（公告）日：2022-01-25

  The present invention relates to herbicidally active pyridyl-/pyrimidyl-pyrazine derivatives, as well as to processes and intermediates used for the preparation of such derivatives. The invention further extends to herbicidal compositions comprising such derivatives, as well as to the use of such compounds and compositions in controlling undesirable plant growth: in particular the use in controlling weeds, in crops of useful plants.

  本发明涉及具有除草活性的吡啶/嘧啶-吡嗪衍生物，以及用于制备此类衍生物的工艺和中间体。 本发明还涉及包含此类衍生物的除草组合物，以及此类化合物和组合物在控制不良植物生长方面的用途：特别是在控制有用植物作物中的杂草方面的用途。