bis(4-fluorophenyl) malonate | 1810-25-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 英文名称: bis(4-fluorophenyl) malonate
• 英文别名: di-p-fluorophenyl malonate；Malonsaeure-bis-<4-fluor-phenylester>；Malonsaeure-bis-(4-fluor-phenylester)；Bis(4-fluorophenyl) propanedioate
• CAS: 1810-25-9
• 化学式: C₁₅H₁₀F₂O₄
• 分子量: 292.239
• InChiKey: PDHGCIFJFVNTSP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  21
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  bis(4-fluorophenyl) malonate 在 三氯化铝 、 硫酸 作用下， 反应 2.17h， 生成 6-氟-4-羟基香豆素
  参考文献：
  名称：

  氟化4-羟基香豆素的简便合成

  摘要：

  通过AlCl 3催化的Friedel-Crafts闭环反应，由容易获得的氟化酚制备氟化4-羟基香豆素，然后依次进行一锅脱羧和90％H 2 SO 4脱乙酰。

  DOI：

  10.1016/0040-4039(96)00101-3
• 作为产物：
  描述：

  4-氟苯酚 、 丙二酸 在 三氯氧磷 作用下， 以90%的产率得到bis(4-fluorophenyl) malonate
  参考文献：
  名称：

  氟化4-羟基香豆素的简便合成

  摘要：

  通过AlCl 3催化的Friedel-Crafts闭环反应，由容易获得的氟化酚制备氟化4-羟基香豆素，然后依次进行一锅脱羧和90％H 2 SO 4脱乙酰。

  DOI：

  10.1016/0040-4039(96)00101-3

文献信息

• Synthesis and structures of the CH acid salts obtained in the reactions of malonic acid esters and malononitriles with 2,4,6-trinitrohalobenzenes in the presence of triethylamine
  作者：Yu. G. Gololobov、S. V. Barabanov、A. S. Peregudov、P. V. Petrovskii、Z. A. Starikova、V. N. Khrustalev、I. A. Garbuzova

  DOI：10.1007/s11172-011-0249-x

  日期：2011.8

  Reactions of dimethyl malonate, diphenyl malonate, methyl cyanoacetate, and malononitrile with 1-chloro-2,4,6-trinitrobenzene or 1-fluoro-2,4,6-trinitrobenzene in the presence of triethylamine in organic solvents gave stable brightly colored crystalline triethylammonium salts of the corresponding 2,4,6-trinitrophenylmalonic acid derivatives.

  丙二酸二甲酯、丙二酸二苯酯、氰基乙酸甲酯和丙二腈与 1-氯-2,4,6-三硝基苯或 1-氟-2,4,6-三硝基苯在有机溶剂中在三乙胺存在下反应，得到稳定的亮色结晶相应的 2,4,6-三硝基苯基丙二酸衍生物的三乙基铵盐。
• Danek,O., Collection of Czechoslovak Chemical Communications, 1964, vol. 29, p. 1035 - 1041
  作者：Danek,O.

  DOI：——

  日期：——
• NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE USING SAME
  申请人：Abe Koji

  公开号：US20140154587A1

  公开（公告）日：2014-06-05

  The present invention provides a nonaqueous electrolytic solution capable of improving electrochemical characteristics in a broad temperature range, such as low-temperature cycle properties and low-temperature discharge properties after high-temperature storage, and provides an energy storage device using the nonaqueous electrolytic solution. The invention includes (1) a nonaqueous electrolytic solution of an electrolyte salt dissolved in a nonaqueous solvent, which comprises from 0.001 to 10% by mass of a compound represented by the following general formula (I), and (2) an energy storage device comprising a positive electrode, a negative electrode, and a nonaqueous electrolytic solution of an electrolyte salt dissolved in a nonaqueous solvent, wherein the nonaqueous electrolytic solution is the nonaqueous electrolytic solution of (1). (In the formula, Y represents a group —C(═O)— or a group —S(═O) 2 —; R 3 and R 4 each independently represent an aryl group having from 6 to 10 carbon atoms in which at least one hydrogen atom is substituted with a halogen atom, or R 3 and R 4 bonding to each other represent a cycloalkanediyl group or a benzenediyl group, having from 5 to 12 carbon atoms. R represents —C(R 1 )(R 2 )— or -L-; R 1 and R 2 each independently represent a hydrogen atom, a halogen atom, or an alkyl group having from 1 to 4 carbon atoms; and L represents a divalent linking group having from 1 to 6 carbon atoms and optionally substituted with a halogen atom.)
• US9236635B2
  申请人：——

  公开号：US9236635B2

  公开（公告）日：2016-01-12
• Highly enantioselective introduction of bis(alkoxycarbonyl)methyl group into the 2-position of piperidine skeleton
  作者：Yoshihiro Matsumura、Diashirou Minato、Osamu Onomura

  DOI：10.1016/j.jorganchem.2006.04.039

  日期：2007.1

  Copper ion catalyzed carbon-carbon bond forming reaction of N-acyliminium ions with diaryl the method were 2-methoxy-3,4-didehydropiperidines, which were easily prepared through electrochemical oxidation of 1-(p-methoxybenzoyl)piperidine in methanol followed by the conversion of the oxidation product to didehydropiperidine derivative, which was subjected to a chiral Cu(II) catalyzed coupling reaction with diaryl malonates affording diaryl 2-piperidylmalonates. The maximum % ee (ee, enantiomeric excess) was 97% when di-p-chlorophenyl malonate was used as a nucleophile. (c) 2006 Elsevier B.V. All rights reserved.