1-(3-Methoxy-4-methylphenyl)ethan-1-amine | 105321-43-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1-(3-Methoxy-4-methylphenyl)ethan-1-amine
• 英文别名: 1-(3-methoxy-4-methylphenyl)ethanamine
• CAS: 105321-43-5
• 化学式: C₁₀H₁₅NO
• 分子量: 165.23
• InChiKey: NABWFJJQFVDVDM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  35.2
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• CATALYST COMPOUNDS
  申请人：THE UNIVERSITY OF LIVERPOOL

  公开号：US20150073165A1

  公开（公告）日：2015-03-12

  The present invention relates to an iridium-based catalyst compound for hydrogenating reducible moieties, especially imines and iminiums, the catalyst compounds being defined by the formula: (Formula (I)) where ring B is a conjugated ring system with one or more substituents. The catalysts of the invention are particularly effective in reductive amination procedures which involve the in situ generation of the imine or iminium under reductive hydrogenative conditions.

  本发明涉及一种基于铱的催化剂化合物，用于氢化可还原基团，特别是亚胺和亚胺盐，所述催化剂化合物由以下公式定义：（公式（I）），其中环B是一个带有一个或多个取代基的共轭环系统。本发明的催化剂在涉及在还原氢化条件下原位生成亚胺或亚胺盐的还原胺化过程中特别有效。
• Triazine Derivatives, a process for preparing the derivatives, and herbicides containing the derivatives as the effective component
  申请人：IDEMITSU KOSAN COMPANY LIMITED

  公开号：EP0191496A2

  公开（公告）日：1986-08-20

  A triazine derivative represented by the general formula: wherein R1 and R2 are each an alkyl group having 1 to 4 carbon atoms, and X1 and X2 are each a halogen atom, an alkyl group having 1 to 4 carbon atoms, an alkoxyl group having 1 to 4 carbon atoms, or an alkylthio group having 1 to 4 carbon atoms. This invention also provides a process for efficiently preparing said triazine derivative and a herbicide containing said triazine derivative as effective component.

  由通式代表的三嗪衍生物： 其中 R1 和 R2 分别为具有 1 至 4 个碳原子的烷基，X1 和 X2 分别为卤素原子、具有 1 至 4 个碳原子的烷基、具有 1 至 4 个碳原子的烷氧基或具有 1 至 4 个碳原子的烷硫基。 本发明还提供了一种高效制备所述三嗪衍生物和含有所述三嗪衍生物作为有效成分的除草剂的工艺。
• Chemical compounds
  申请人：AstraZeneca AB

  公开号：US10590130B2

  公开（公告）日：2020-03-17

  The specification relates to compounds of Formula (I): and to pharmaceutically acceptable salts thereof, to processes and intermediates used for their preparation, to pharmaceutical compositions containing them and to their use in the treatment of cell proliferative disorders.

  本说明书涉及式 (I) 化合物： 及其药学上可接受的盐、用于制备它们的工艺和中间体、含有它们的药物组合物以及它们在治疗细胞增殖性疾病中的用途。
• SYNTHESIS OF AMIDES AND AMINES FROM ALDEHYDES OR KETONES BY HETEROGENEOUS METAL CATALYSIS
  申请人：ORGANOFUEL SWEDEN AB

  公开号：US20170362162A1

  公开（公告）日：2017-12-21

  A mild and efficient synthesis of primary amines and amides from aldehydes or ketones using a heterogeneous metal catalyst and amine donor is disclosed. The initial heterogeneous metal-catalyzed reaction between the carbonyl and the amine donor components is followed by the addition of a suitable acylating agent component in one-pot, thus providing a catalytic one-pot three-component synthesis of amides. Integration of enzyme catalysis allows for eco-friendly one-pot co-catalytic synthesis of amides from aldehyde and ketone substrates, respectively. The process can be applied to asymmetric synthesis or to the co-catalytic one-pot three-component synthesis of capsaicin and its analogues from vanillin or vanillyl alcohol. A co-catalytic reductive amination/dynamic kinetic resolution (dkr) relay sequence for the asymmetric synthesis of optically active amides from ketones is disclosed. Implementation of a catalytic reductive amination/kinetic resolution (kr) relay sequence produces the corresponding optically active amide product and optical active primary amine product with the opposite stereochemistry from the starting ketones.
• US4680054A
  申请人：——

  公开号：US4680054A

  公开（公告）日：1987-07-14