3-(diphenylphosphino)-4-methylstyrene | 623943-05-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-(diphenylphosphino)-4-methylstyrene
• 英文别名: 3-(Diphenylphosphino)-4-methyl-styrene；(5-ethenyl-2-methylphenyl)-diphenylphosphane
• CAS: 623943-05-5
• 化学式: C₂₁H₁₉P
• 分子量: 302.356
• InChiKey: QNDQOJDZXZXKRC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  palladium diacetate 、 3-(diphenylphosphino)-4-methylstyrene 以 甲苯 为溶剂， 反应 0.08h， 以74%的产率得到trans-di(μ-acetato)-bis[3-(diphenylphosphino)-4-styryl]dipalladium(II)
  参考文献：
  名称：

  Polystyrene-supported palladacycle catalysts

  摘要：

  本发明涉及一种可回收的钯环化合物催化剂，其化学式为其中每个是单键或双键，前提是如果其中一个是双键，则其相邻的不是双键；每个X和Z独立地是-P（R′）-，-S-，-N（R′）-或-N═，其中R′是烷基，芳基，环烷基，杂芳基或杂环烷基；每个Y1和Y2独立地是有机或无机酸的阴离子；每个X1、X2、X3、Z1、Z2和Z3独立地是-C═或-CR″-，其中R″是H，烷基，芳基，环烷基，杂芳基或杂环烷基；每个R1、R2、R3、R4、R5、R6、R7和R8独立地是H，烷基，芳基，环烷基，杂芳基或杂环烷基，或者R1、X、X1和R2一起形成一个3-8成员环，或者R2、X1、X2和R3一起形成一个3-8成员环，或者R3、X2、X3和R4一起形成一个3-8成员环，或者R5、Z、Z1和R6一起形成一个3-8成员环，或者R6、Z1、Z2和R7一起形成一个3-8成员环，或者R7、Z2、Z3和R8一起形成一个3-8成员环；前提是R1、R2、R3、R4、R5、R6、R7和R8中的一个，或由R1、X、X1和R2形成的环，或由R2、X1、X2和R3形成的环，或由R3、X2、X3和R4形成的环，或由R5、Z、Z1和R6形成的环，或由R1、Z1、Z2和R7形成的环，或由R7、Z2、Z3和R8形成的环之一连接到第一个聚合物。本发明还包括使用上述钯环化合物促进偶联反应的方法以及制备该化合物的方法。

  公开号：

  US20060004216A1
• 作为产物：
  描述：

  3'-溴-4'-甲基苯乙酮 在 potassium hydrogensulfate 、 lithium aluminium tetrahydride 、 magnesium 、 对苯二酚 作用下， 以 四氢呋喃 、 乙醚 为溶剂， 生成 3-(diphenylphosphino)-4-methylstyrene
  参考文献：
  名称：

  Polystyrene-supported recyclable palladacycle catalyst for Heck, Suzuki and Sonogashira reactions

  摘要：

  A new type of soluble polystyrene-supported palladium complex as an excellent and recyclable palladacycle catalyst was discovered for carbon-carbon bond formation in Heck, Suzuki and Sonogashira reactions. Precipitation and filtration process for recycling the catalyst was also achieved. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2003.08.069

文献信息

• Polystyrene-supported recyclable palladacycle catalyst for Heck, Suzuki and Sonogashira reactions
  作者：Chih-An Lin、Fen-Tair Luo

  DOI：10.1016/j.tetlet.2003.08.069

  日期：2003.10

  A new type of soluble polystyrene-supported palladium complex as an excellent and recyclable palladacycle catalyst was discovered for carbon-carbon bond formation in Heck, Suzuki and Sonogashira reactions. Precipitation and filtration process for recycling the catalyst was also achieved. (C) 2003 Elsevier Ltd. All rights reserved.
• US7115762B2
  申请人：——

  公开号：US7115762B2

  公开（公告）日：2006-10-03
• Polystyrene-supported palladacycle catalysts
  申请人：Luo Fen-Tair

  公开号：US20060004216A1

  公开（公告）日：2006-01-05

  This invention relates to a recyclable palladacycle catalyst of formula in which each is a single bond or a double bond, provided that if one is a double bond, its neighboring is not a double bond; each of X and Z, independently, is —P(R′)—, —S—, —N(R′)—, or —N═, in which R′ is alkyl, aryl, cyclyl, heteroaryl, or heterocyclyl; each of Y 1 and Y 2 , independently, is an anion of an organic or inorganic acid; each of X 1 , X 2 , X 3 , Z 1 , Z 2 , and Z 3 , independently, is —C═, —CR″—, in which R″ is H, alkyl, aryl, cyclyl, heteroaryl, or heterocyclyl; and each of R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , and R 8 , independently, is H, alkyl, aryl, cyclyl, heteroaryl, or heterocyclyl, or R 1 , X, X 1 , and R 2 , together form a 3-8 membered ring, or R 2 , X 1 , X 2 , and R 3 , together form a 3-8 membered ring, or R 3 , X 2 , X 3 , and R 4 , together form a 3-8 membered ring, or R 5 , Z, Z 1 , and R 6 , together form a 3-8 membered ring, or R 6 , Z 1 , Z 2 , and R 7 , together form a 3-8 membered ring, or R 7 , Z 2 , Z 3 , and R 8 , together form a 3-8 membered ring; provided that one of R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , and R 8 , or the ring formed from R 1 , X, X 1 , and R 2 , or the ring formed from R 2 , X 1 , X 2 , and R 3 , or the ring formed from R 3 , X 2 , X 3 , and R 4 , or the ring formed from R 5 , Z, Z 1 , and R 6 , or the ring formed from R 1 , Z 1 , Z 2 , and R 7 , or the ring formed from R 7 , Z 2 , Z 3 , and R 8 is connected to a first polymer. Also included in this invention are a method of promoting a coupling reaction using the above-described palladacycle compound and a method of making it.

  本发明涉及一种可回收的钯环化合物催化剂，其化学式为其中每个是单键或双键，前提是如果其中一个是双键，则其相邻的不是双键；每个X和Z独立地是-P（R′）-，-S-，-N（R′）-或-N═，其中R′是烷基，芳基，环烷基，杂芳基或杂环烷基；每个Y1和Y2独立地是有机或无机酸的阴离子；每个X1、X2、X3、Z1、Z2和Z3独立地是-C═或-CR″-，其中R″是H，烷基，芳基，环烷基，杂芳基或杂环烷基；每个R1、R2、R3、R4、R5、R6、R7和R8独立地是H，烷基，芳基，环烷基，杂芳基或杂环烷基，或者R1、X、X1和R2一起形成一个3-8成员环，或者R2、X1、X2和R3一起形成一个3-8成员环，或者R3、X2、X3和R4一起形成一个3-8成员环，或者R5、Z、Z1和R6一起形成一个3-8成员环，或者R6、Z1、Z2和R7一起形成一个3-8成员环，或者R7、Z2、Z3和R8一起形成一个3-8成员环；前提是R1、R2、R3、R4、R5、R6、R7和R8中的一个，或由R1、X、X1和R2形成的环，或由R2、X1、X2和R3形成的环，或由R3、X2、X3和R4形成的环，或由R5、Z、Z1和R6形成的环，或由R1、Z1、Z2和R7形成的环，或由R7、Z2、Z3和R8形成的环之一连接到第一个聚合物。本发明还包括使用上述钯环化合物促进偶联反应的方法以及制备该化合物的方法。
• Preparation of polystyrene-supported soluble palladacycle catalyst for Heck and Suzuki reactions
  作者：Fen-Tair Luo、Cuihua Xue、Sheng-Li Ko、Yu-Der Shao、Chien-Jung Wu、Yang-Ming Kuo

  DOI：10.1016/j.tet.2005.04.036

  日期：2005.6

  A polystyrene-supported palladium complex soluble in tetrahydrofuran and N,N-dimethylacetamide and precipitated in diethyl ether or acetonitrile was prepared from two routes as an excellent and recyclable palladacycle catalyst for carbon-carbon bond formation in Heck and Suzuki reactions to give high yields of the desired products. (c) 2005 Elsevier Ltd. All rights reserved.