2,4-bis(1,1-dimethylethyl)-6-[(4-methoxyphenyl)methyl]phenol | 71712-03-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,4-bis(1,1-dimethylethyl)-6-[(4-methoxyphenyl)methyl]phenol
• 英文别名: 2,4-bis(1,1-dimethylethyl)-6-<(4-methoxyphenyl)methyl>phenol；2,4-bis(1,1-dimethylethyl)-6-(4-methoxyphenylmethyl)phenol；2,4-di-tert-butyl-6-(4'-methoxybenzyl)phenol；4,6-Di-t-butyl-2-(4-methoxybenzyl)-phenol；2,4-di-tert-butyl-6-(4-methoxybenzyl)-phenol；4,6-Di-t-butyl-2-(4-methoxybenzyl) phenol；2,4-di-tert-Butyl-6-(4-methoxybenzyl)phenol；2,4-ditert-butyl-6-[(4-methoxyphenyl)methyl]phenol
• CAS: 71712-03-3
• 化学式: C₂₂H₃₀O₂
• 分子量: 326.479
• InChiKey: DLDDIHRRFIDSOW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.8
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,4-bis(1,1-dimethylethyl)-6-[(4-methoxyphenyl)methyl]phenol 在 三溴化硼 、 sodium hydride 作用下， 以 二氯甲烷 为溶剂， 反应 1.0h， 生成 2,4-di-tert-butyl-6-(4'-hydroxybenzyl)phenol
  参考文献：
  名称：

  Substituent effects on chemosterilant activity of 2,4-di-tert-butyl-6-(4'-substituted benzyl)phenols in the house fly (Musca domestica L.)

  摘要：

  A series of 2,4-di-tert-butyl-6-(4'-X-benzyl)phenols was prepared, analogous to the compound Jurd 2644 (X = OMe) in an attempt to establish a Hammett relationship between the 4'-substituent and the chemosterilant activity of the compounds after oral administration to adult Musca domestica. Fourteen compounds of this type were prepared, 12 of them new. Jurd 2419 (X = H) was found to be as active in our bioassay as Jurd 2644, as were four new compounds [X = N(CH3)(2), CH3, SCH3, Cl]. All prevented successful reproduction at 30 mg/kg of diet. There was no correlation between Hammett a and activity. Active compounds all had small substituents and molecular weights below 350. The activity seemed to be determined by the bulk of X rather than by its electronic properties.

  DOI：

  10.1021/jf00059a037
• 作为产物：
  描述：

  2,4-二叔丁基苯酚 、 4-甲氧基苄醇 在 亚磷酸 水 、 甲醇 作用下， 以 甲苯 为溶剂， 反应 1.0h， 生成 2,4-bis(1,1-dimethylethyl)-6-[(4-methoxyphenyl)methyl]phenol
  参考文献：
  名称：

  Dibutylorthobenzylmethoxybenzenes and

  摘要：

  本发明涉及一种具有以下结构的新型二丁基正邻苯甲氧基苯的化合物，其中R为氢、低级烷基或低级烷氧基，以及新型的二丁基正邻肉桂基甲氧基苯化合物，作为蚊虫幼虫的生长抑制剂。

  公开号：

  US04391828A1

文献信息

• Polybutylbenzylphenols and benzyl-3,4-methylenedioxybenzenes in insect
  申请人：The United States of America as represented by the Secretary of

  公开号：US04342777A1

  公开（公告）日：1982-08-03

  Certain polybutylbenzylphenols and benzyl-3,4-methylenedioxybenzenes are useful for insect control especially as insect chemosterilants and oviposition inhibitors. The benzyl-3,4-methylenedioxybenzenes also find utility as growth inhibitors for mosquito larvae.

  某些聚丁基苯基苯酚和苯基-3,4-亚甲二氧基苯酚对昆虫控制特别有用，尤其作为昆虫化学不育剂和产卵抑制剂。苯基-3,4-亚甲二氧基苯酚也可作为蚊子幼虫的生长抑制剂。
• Amorphous Amides
  申请人：Xerox Corporation

  公开号：US20150105587A1

  公开（公告）日：2015-04-16

  An amorphous amide compound of the formula wherein R is selected from the group consisting of an alkyl group, an aryl group, an alkylaryl group, an arylalkyl group, and combinations thereof. An amorphous diamide compound of the formula wherein R 1 is selected from the group consisting of an alkylene group, an arylene group, an alkylarylene group, an arylalkylene group, and combinations thereof.

  一个无定形的酰胺化合物的化学式，其中R从包括烷基、芳基、烷基芳基、芳基烷基及其组合的群体中选择。一个无定形的二酰胺化合物的化学式，其中R1从包括亚烷基、亚芳基、烷基亚芳基、芳基烷亚基及其组合的群体中选择。
• Quinones and quinone methides. VIII. Oxidation products of the screwworm chemosterilant, 2,4-Bis(1,1-dimethylethyl)-6-(4-methoxyphenylmethyl)phenol
  作者：L Jurd、RY Wong

  DOI：10.1071/ch9811633

  日期：——

  The title compound is oxidized by silver oxide in acetone to a complex mixture of products, including the benzophenone derivative (7), a benzylic alcohol, isolated as its methyl ether (15), and two spiro cyclohexadienone benzopyran dimers (17) and (19). A colourless dimer was shown by single-crystal X-ray diffraction measurements to be a 2,3- dihydrobenzofuran derivative (22).

  标题化合物 在丙酮中被氧化银氧化，生成复杂的混合物，包括 二苯甲酮衍生物 (7)、一种苯甲醇（以其甲醚形式分离出来）(15) 醚 (15) 以及两种螺环己二烯酮苯并吡喃二聚体 (17) 和 (19)。一种无色 单晶 X 射线衍射测量结果表明，该二聚体是一种 2,3-二氢苯并呋喃衍生物 (22)。 衍生物 (22)。
• PHASE CHANGE INK COMPONENTS AND METHODS OF MAKING THE SAME
  申请人：BELELIE JENNIFER L.

  公开号：US20120291663A1

  公开（公告）日：2012-11-22

  A solid ink composition comprising an amorphous component, a crystalline material, and optionally, a colorant, which are suitable for ink jet printing, including printing on coated paper substrates, and methods for making the same. In embodiments, the crystalline and amorphous components are synthesized from an esterification reaction of tartaric acid with an alcohol.

  一种固体油墨组合物，包括无定形组分、结晶材料，以及可选的着色剂，适用于喷墨打印，包括在涂布纸基底上打印，并且制备方法。在实施例中，结晶和无定形组分是通过酒石酸与醇的酯化反应合成的。
• Polybutylbenzylphenols and benzyl-3,4-methylenedioxbenzenes in insect
  申请人：The United States of America as represented by the Secretary of

  公开号：US04482728A1

  公开（公告）日：1984-11-13

  Certain polybutylbenzylphenols and benzyl-3,4-methylenedioxybenzenes are useful for insect control especially as insect chemosterilants and oviposition inhibitors. The benzyl-3,4-methylenedioxybenzenes also find utility as growth inhibitors for mosquito larvae.

  某些聚丁基苯基酚和苯基-3,4-亚甲二氧基苯对昆虫控制特别有用，尤其是作为昆虫化学不育剂和产卵抑制剂。苯基-3,4-亚甲二氧基苯也可作为蚊幼虫生长抑制剂使用。

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