4-((2-hydroxyethylthio)methyl)-2,6-di-tert-butylphenol | 4103-72-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-((2-hydroxyethylthio)methyl)-2,6-di-tert-butylphenol
• 英文别名: 2,6-Di-tert-butyl-4-(β-hydroxyethylthiomethyl)phenol；2,6-Di-t-butyl-4-{[(2-hydroxyethyl)thio]methyl}phenol；2,6-ditert-butyl-4-(2-hydroxyethylsulfanylmethyl)phenol
• CAS: 4103-72-4
• 化学式: C₁₇H₂₈O₂S
• 分子量: 296.474
• InChiKey: DWTMBRKEIMVHSQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  20
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  65.8
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-((2-hydroxyethylthio)methyl)-2,6-di-tert-butylphenol 、 三氯化磷 以85%的产率得到
  参考文献：
  名称：

  AXMEDZADE D. A.; SAXNOVSKAYA E. B.; SHAMXALOVA A. A.; BABAEVA S. G., IN-T NEFTEXIM. PROTSESSOV AN AZSSR. BAKU, 1979. 5 S., BIBLIOGR. 4 NAZV. (+

  摘要：

  DOI：
• 作为产物：
  描述：

  聚合甲醛 、 2,6-二叔丁基苯酚 、 2-巯基乙醇 在 2,6-di-tert-butyl-4-(dimethylaminomethyl)phenol 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 15.0h， 以53%的产率得到4-((2-hydroxyethylthio)methyl)-2,6-di-tert-butylphenol
  参考文献：
  名称：

  Catalytic Thioalkylation of Phenols Based on Mannich‐Type Phenol

  摘要：

  A thioalkylation of phenols involving reactive phenols, aldehydes, and thiols is described under Mannich-type phenol catalysis to afford thiomethyl phenols in good yields.

  DOI：

  10.1080/00397910701462971

文献信息

• Synthesis of thiomethyl-substituted 2,6-di-tert-butylphenols via the domino reaction between thiols, N,N,N′,N′-tetraethylmethylene diamine, and 2,6-di-tert-butylphenol
  作者：S. E. Yagunov、O. I. Prosenko

  DOI：10.1007/s11172-022-3704-y

  日期：2022.12

  Heating of thiols, N,N,N′,N′-tetraethylmethylene diamine, and phenols in DMF affords thiomethyl-substituted phenols in high yields. The developed procedure performed well for aliphatic, aromatic, and functionalized thiols.

  在 DMF 中加热硫醇、N,N,N′,N′-四亚甲基二胺和苯酚，可获得高产率的硫代甲基苯酚。所开发的程序对脂肪族、芳香族和官能化硫醇都有很好的效果。
• Functionalised polymers
  申请人：——

  公开号：US20020123577A1

  公开（公告）日：2002-09-05

  This invention relates to a process for stabilizing and at the same time phase compatibilising plastics or plastic compositions by incorporating polymeric compounds obtainable by reacting a compound selected from the group consisting of the sterically hindered phenols, sterically hindered amines, lactones, sulfides, phosphites, benzotriazoles, benzophenones and 2-(2-hydroxyphenyl)-1,3,5-triazines, which compounds contain at least one reactive group, with a compatibilisator.

  本发明涉及一种稳定并同时相容塑料或塑料组合物的工艺，其方法是将选自立体受阻酚、立体受阻胺、内酯、硫化物、亚磷酸盐、苯并三唑、二苯甲酮和 2-(2-羟基苯基)-1,3,5-三嗪（这些化合物至少含有一个活性基团）组中的化合物与相容剂反应而得到的聚合物化合物结合在一起。
• AXMEDZADE D. A.; SAXNOVSKAYA E. B.; SHAMXALOVA A. A.; BABAEVA S. G., AZEHRB. KIMJA ZH., AZERB. XIM. ZH. 1980, HO 5, 55-57
  作者：AXMEDZADE D. A.、 SAXNOVSKAYA E. B.、 SHAMXALOVA A. A.、 BABAEVA S. G.

  DOI：——

  日期：——
• FUNCTIONALISED POLYMERS
  申请人：Ciba Specialty Chemicals Holding Inc.

  公开号：EP0935619A1

  公开（公告）日：1999-08-18
• Functionalized polymers
  申请人：PFAENDNER Rudolf

  公开号：US20080051521A1

  公开（公告）日：2008-02-28

  This invention relates to a process for stabilising and at the same time phase compatibilising plastics or plastic compositions by incorporating polymeric compounds obtainable by reacting a compound selected from the group consisting of the sterically hindered phenols, sterically hindered amines, lactones, sulfides, phosphites, benzotriazoles, benzophenones and 2-(2-hydroxyphenyl)-1,3,5-triazines, which compounds contain at least one reactive group, with a compatibilisator.