3-Methyl-3,4,5,6-tetrahydropyridin-2-amine | 165383-76-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 3-Methyl-3,4,5,6-tetrahydropyridin-2-amine
• 英文别名: 5-methyl-2,3,4,5-tetrahydropyridin-6-amine
• CAS: 165383-76-6
• 化学式: C₆H₁₂N₂
• mdl: MFCD13176139
• 分子量: 112.17
• InChiKey: KWOSGUYHQQCIGP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.833
• 拓扑面积：
  38.4
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Pyrimidones for Treatment of Potassium Channel Related Diseases
  申请人：Sakurada Isao

  公开号：US20130184294A1

  公开（公告）日：2013-07-18

  The present invention relates to compounds of Formula I as described herein or a pharmaceutically acceptable salt thereof, pharmaceutical composition comprising a compound of Formula I or a pharmaceutically acceptable salt thereof and methods of treating a disease, disorder, or condition of the central nervous system, including bipolar disorder, depressive disorders, anxiety disorders, cognitive disorders, pain disorders, urogenital disorders, and epilepsy, among the other diseases, disorders or conditions discussed herein as mono-therapy or in combination with another active pharmaceutical ingredient.

  本发明涉及公式I所述的化合物或其药学上可接受的盐，包括公式I化合物或其药学上可接受的盐的制药组合物以及治疗中枢神经系统疾病、失调或病症的方法，包括双相情感障碍、抑郁症、焦虑症、认知障碍、疼痛障碍、泌尿生殖系统障碍和癫痫等其他在此处讨论的疾病、失调或病症，作为单一治疗或与另一种活性药物成分联合使用。
• Amidino derivatives useful as nitric oxide synthase inhibitors
  申请人：G.D. SEARLE & CO.

  公开号：EP0897912A1

  公开（公告）日：1999-02-24

  The current invention discloses useful pharmaceutical compositions containing amidino derivatives of formula (I) as nitric oxide synthase inhibitors.

  本发明公开了含有式（I）脒基衍生物作为一氧化氮合酶抑制剂的有用药物组合物。
• ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND
  申请人：Samsung Electronics Co., Ltd.

  公开号：EP3461830A1

  公开（公告）日：2019-04-03

  An organometallic compound represented by Formula 1: wherein, in Formula 1, groups and variables are the same as described in the specification.

  由式 1 表示的有机金属化合物： 其中，式 1 中的基团和变量与说明书中描述的相同。
• AMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS
  申请人：G.D. SEARLE & CO.

  公开号：EP0724570A1

  公开（公告）日：1996-08-07
• PYRIDMIDONES FOR TREATMENT OF POTASSIUM CHANNEL RELATED DISEASES
  申请人：Pfizer Inc.

  公开号：EP2619202A1

  公开（公告）日：2013-07-31