2,3-diethyl-1-phenylphosphol-2-ene | 1259008-71-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,3-diethyl-1-phenylphosphol-2-ene
• 英文别名: 2,3-diethyl-1-phenyl-4,5-dihydrophosphole；4,5-Diethyl-1-phenyl-2,3-dihydrophosphole；4,5-diethyl-1-phenyl-2,3-dihydrophosphole
• CAS: 1259008-71-3
• 化学式: C₁₄H₁₉P
• 分子量: 218.279
• InChiKey: RDYOALKSXXRGRZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  2,3-diethyl-1-phenylphosphol-2-ene 在 1,2,3,4,5,6,7,8-八硫杂环辛烷 作用下， 以 甲苯 为溶剂， 以100%的产率得到4,5-diethyl-1-phenyl-2,3-dihydro-1H-phosphole 1-sulfide
  参考文献：
  名称：

  Targeted synthesis of 2,3-disubstituted 2-phospholenes using catalytic cycloalumination of acetylenes

  摘要：

  A preparative one-pot method for the synthesis of 2,3-dialkyl-substituted phosphol-2-enes by catalytic cycloalumination of symmetric acetylenes with AlEt3 catalyzed by Cp2ZrCl2 is developed. The reaction gives the corresponding aluminacyclopentenes, which then react in situ with phosphorus dihalides. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2014.05.029
• 作为产物：
  描述：

  、 苯基二氯化磷 以 甲苯 为溶剂， 反应 0.5h， 以174 mg的产率得到2,3-diethyl-1-phenylphosphol-2-ene
  参考文献：
  名称：

  Targeted synthesis of 2,3-disubstituted 2-phospholenes using catalytic cycloalumination of acetylenes

  摘要：

  A preparative one-pot method for the synthesis of 2,3-dialkyl-substituted phosphol-2-enes by catalytic cycloalumination of symmetric acetylenes with AlEt3 catalyzed by Cp2ZrCl2 is developed. The reaction gives the corresponding aluminacyclopentenes, which then react in situ with phosphorus dihalides. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2014.05.029

文献信息

• Epoxidation of 4,5-dialkyl-2,3-dihydro-1Н-phosphole 1-oxides
  作者：Vladimir A. D’yakonov、Rina A. Agliullina、Alevtina L. Makhamatkhanova、Tatyana V. Tyumkina、Usein M. Dzhemilev

  DOI：10.1007/s10593-018-2255-5

  日期：2018.2

  A method was developed for the synthesis of 1,5-dialkyl(cycloalkyl,phenyl)-2-phenyl-6-oxa-2-phosphabicyclo[3.1.0]hexane 2-oxides from alkynes, involving the epoxidation of unsaturated cyclic organophosphorus compounds with m-chloroperbenzoic acid. The organophosphorus compounds were obtained by a reaction sequence consisting of catalytic cycloalumination of symmetrical acetylenes with triethylaluminum

  开发了一种从炔烃合成1,5-二烷基（环烷基，苯基）-2-苯基-6-氧杂-2-磷双环[3.1.0]己烷2-氧化物的方法，该方法涉及不饱和环状有机磷化合物的环氧化与米氯过苯甲酸。有机磷化合物是通过在双（环戊二烯基）二氯化锆（IV）催化剂存在下，对称乙炔与三乙基铝催化环铝反应而形成的，从而导致2,3-二取代的氧化铝环戊-2-烯的形成和原位反应。后者与二氯苯基膦反应。
• Preparation of 2-phospholene derivatives from zirconacyclopentenes
  作者：Yiqing Zhou、Xiaoyu Yan、Chanjuan Xi

  DOI：10.1016/j.tetlet.2010.09.061

  日期：2010.11

  Zirconacyclopentenes, which are easily prepared from alkynes, alkenes, and zirconocene compounds, reacted with dichlorophenylphosphine to give 2-phospholene in high yields. The reaction was performed conveniently in one-pot from an alkyne, alkene, dichlorophosphine, and zirconocene compounds. (C) 2010 Elsevier Ltd. All rights reserved.
• Targeted synthesis of 2,3-disubstituted 2-phospholenes using catalytic cycloalumination of acetylenes
  作者：Vladimir A. D’yakonov、Alevtina L. Makhamatkhanova、Rina A. Agliullina、Tat’yana V. Tyumkina、Usein M. Dzhemilev

  DOI：10.1016/j.tetlet.2014.05.029

  日期：2014.7

  A preparative one-pot method for the synthesis of 2,3-dialkyl-substituted phosphol-2-enes by catalytic cycloalumination of symmetric acetylenes with AlEt3 catalyzed by Cp2ZrCl2 is developed. The reaction gives the corresponding aluminacyclopentenes, which then react in situ with phosphorus dihalides. (C) 2014 Elsevier Ltd. All rights reserved.