3,6-Anhydro-2-O-methyl-L-galactose | 18404-85-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧唑烯
• 英文名称: 3,6-Anhydro-2-O-methyl-L-galactose
• 英文别名: O²-Methyl-3,6-anhydro-L-galactose；2-O-Methyl-3,6-anhydro-L-galactose；(2S)-2-[(2R,3R,4S)-3,4-dihydroxyoxolan-2-yl]-2-methoxyacetaldehyde
• CAS: 18404-85-8
• 化学式: C₇H₁₂O₅
• 分子量: 176.169
• InChiKey: FBPJLXHKDJMMOY-WNJXEPBRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.9
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  76
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  O²-Methyl-3,6-anhydro-L-galactose-dimethylacetal 在 硫酸 作用下， 生成 3,6-Anhydro-2-O-methyl-L-galactose
  参考文献：
  名称：

  Araki, Nippon Kagaku Kaishi/Journal of the Chemical Society of Japan, 1940, vol. 61, p. 775,779

  摘要：

  DOI：

文献信息

• DRUGS, FOODS OR DRINKS WITH THE USE OF ALGAE-DERIVED PHYSIOLOGICALLY ACTIVE SUBSTANCES
  申请人：Takara Shuzo Co, Ltd.

  公开号：EP1038879A1

  公开（公告）日：2000-09-27

  Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose represented by formula (1): foods, drinks, cosmetics, etc. containing as the active ingredient at least one member selected from the group consisting of the above-mentioned compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. This compound also shows, for example, an apoptosis-inducing activity, a carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes it useful also as the active ingredient of antioxidants and preservatives.

  用于治疗、改善或预防对式(1)代表的 3,6-脱水吡喃半乳糖敏感的疾病的药用组合物： 食品、饮料、化妆品等，其有效成分中至少含有一种选自上述化合物、其醛、其水合物及其 2-O-甲基化衍生物和含有上述化合物的可溶性糖类化合物组成的组。例如，这种化合物还具有诱导细胞凋亡的活性、致癌活性以及抑制活性氧、过氧化脂质自由基和 NO 生成的活性，因此也可用作抗氧化剂和防腐剂的活性成分。
• Drugs, foods or drinks with the use of algae-derived physiologically active substances
  申请人：TAKARA SHUZO CO., LTD.

  公开号：US20030105029A1

  公开（公告）日：2003-06-05

  Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose are represented by formula (I): 1 These compositions include foods, drinks, cosmetics, etc. containing as the active ingredient at least one such compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. These compounds show an apoptosis-inducing activity, carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes them useful also as the active ingredient of antioxidants and preservatives.

  用于治疗、改善或预防对 3，6-脱水吡喃半乳糖敏感的疾病的药物组合物由式 (I) 表示： 1 这些组合物包括食品、饮料、化妆品等，其活性成分至少含有一种此类化合物、其醛、其水合物和 2-O-甲基化衍生物，以及含有上述化合物的可溶性糖类化合物。这些化合物具有诱导细胞凋亡的活性、致癌活性以及抑制活性氧、过氧化脂质自由基和 NO 生成的活性，因此也可用作抗氧化剂和防腐剂的活性成分。
• Process for preventing staling of starch-containing composition
  申请人：MEIJI SEIKA KAISHA LTD.

  公开号：EP0237992B1

  公开（公告）日：1992-06-03
• JPH05244908A
  申请人：——

  公开号：JPH05244908A

  公开（公告）日：1993-09-24
• JPS62210958A
  申请人：——

  公开号：JPS62210958A

  公开（公告）日：1987-09-17