(E)-2,6-dichlorobenzophenone oxime | 157491-02-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (E)-2,6-dichlorobenzophenone oxime
• 英文别名: (NE)-N-[(2,6-dichlorophenyl)-phenylmethylidene]hydroxylamine
• CAS: 157491-02-6
• 化学式: C₁₃H₉Cl₂NO
• 分子量: 266.127
• InChiKey: GLALWMVWTDHOGE-DTQAZKPQSA-N

物化性质

• 沸点：
  402.3±45.0 °C(Predicted)
• 密度：
  1.29±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.22
• 重原子数：
  17.0
• 可旋转键数：
  2.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  32.59
• 氢给体数：
  1.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  (E)-2,6-dichlorobenzophenone oxime 生成 N-(2-氯苯基)-苯酰胺
  参考文献：
  名称：

  Auricchio Sergio, Bini Antonella, Pastormerlo Eros, Ricca Aldo, Truscello+, Tetrahedron, 50 (1994) N 25, S 7589-7596

  摘要：

  DOI：
• 作为产物：
  描述：

  2,6-二氯苯甲腈 N-氧化物 、 苯 在 三氟化硼 作用下， 以75%的产率得到(E)-2,6-dichlorobenzophenone oxime
  参考文献：
  名称：

  Nitrile Oxide-BF3 complex as electrophilic moiety towards aromatic systems: Stereospecific synthesis of oximes

  摘要：

  Aromatic Oximes are obtained stereospecifically by action of Nitrile Oxide-BF3 complexes on Aromatic Compounds.

  DOI：

  10.1016/s0040-4020(01)90486-7

文献信息

• Reactions between Nitrile Oxides and Carbenium Ions: Synthesis of Benzoxazines, Oximes, and Amides through Intramolecular ortho or ipso Attack
  作者：Sergio Auricchio、Caterina Magnani、Ada M. Truscello

  DOI：10.1002/1099-0690(200207)2002:14<2411::aid-ejoc2411>3.0.co;2-n

  日期：2002.7

  Reactions between nitrite oxides and benzylic carbocations are described. Different results were obtained when the carbocations were generated from the corresponding chlorides with different Lewis acids, with addition products such as benzoxazines, oximes, and amides being produced. Primary, secondary, and tertiary carbocations showed different reactivities. The product ratios strongly depended on the substituents on the aromatic ring of the benzylic carbocations. Evidence for the proposed mechanism is reported. ((C) Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002).
• Auricchio Sergio, Bini Antonella, Pastormerlo Eros, Ricca Aldo, Truscello+, Tetrahedron, 50 (1994) N 25, S 7589-7596
  作者：Auricchio Sergio, Bini Antonella, Pastormerlo Eros, Ricca Aldo, Truscello+

  DOI：——

  日期：——
• Nitrile Oxide-BF3 complex as electrophilic moiety towards aromatic systems: Stereospecific synthesis of oximes
  作者：Sergio Auricchio、Antonella Bini、Eros Pastormerlo、Aldo Ricca、Ada M. Truscello

  DOI：10.1016/s0040-4020(01)90486-7

  日期：——

  Aromatic Oximes are obtained stereospecifically by action of Nitrile Oxide-BF3 complexes on Aromatic Compounds.