1-methyl-4-(trideuteriomethoxy)benzene | 23346-26-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1-methyl-4-(trideuteriomethoxy)benzene
• 英文别名: 4-Trideuteriomethoxy-toluol；4-Methoxy-d(3)-toluol；<2H3>-Methyl-p-tolyl-ether；Para-cresol deuteromethyl ether
• CAS: 23346-26-1
• 化学式: C₈H₁₀O
• 分子量: 125.143
• InChiKey: CHLICZRVGGXEOD-BMSJAHLVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-methyl-4-(trideuteriomethoxy)benzene 在 N-溴代丁二酰亚胺(NBS) 作用下， 生成 C₈H₆⁽²⁾H₃BrO
  参考文献：
  名称：

  Deuterium Isotope Effect on Bulk Heterojunction Solar Cells. Enhancement of Organic Photovoltaic Performances Using Monobenzyl Substituted Deuteriofullerene Acceptors

  摘要：

  A series of novel monobenzyl-substituted deuteriofullerenes (BnDCs) were synthesized efficiently through Co-catalyzed selective monofunctionalization of C-60. Bulk heterojunction solar cells, based on poly(3-hexylthiophene) as the donor and BnDCs as the acceptors, exhibited higher photovoltaic performances as compared to the corresponding protonated BnHCs devices.

  DOI：

  10.1021/ol4026606
• 作为产物：
  描述：

  甲醇-d3 、 4-碘甲苯 在 copper(ll) bromide 作用下， 生成 1-methyl-4-(trideuteriomethoxy)benzene
  参考文献：
  名称：

  Deuterium Isotope Effect on Bulk Heterojunction Solar Cells. Enhancement of Organic Photovoltaic Performances Using Monobenzyl Substituted Deuteriofullerene Acceptors

  摘要：

  A series of novel monobenzyl-substituted deuteriofullerenes (BnDCs) were synthesized efficiently through Co-catalyzed selective monofunctionalization of C-60. Bulk heterojunction solar cells, based on poly(3-hexylthiophene) as the donor and BnDCs as the acceptors, exhibited higher photovoltaic performances as compared to the corresponding protonated BnHCs devices.

  DOI：

  10.1021/ol4026606

文献信息

• 一种对甲基苯甲醚或其稳定同位素标记物的合成方法
  申请人：上海安谱实验科技股份有限公司

  公开号：CN114075099A

  公开（公告）日：2022-02-22

  本发明公开了一种对甲基苯甲醚或其稳定同位素标记物的合成方法，该合成方法首次利用光延反应，以甲醇或稳定同位素标记的甲醇作为甲基化试剂，与对甲酚在膦试剂和偶氮试剂的作用下，一步反应得到对甲基苯甲醚或其稳定同位素标记物。本发明的合成方法原料价廉易得，毒性低，反应时间短，能耗低，操作简便，稳定同位素不会出现明显稀释现象，产品容易分离提纯，产率高，化学纯度与稳定同位素丰度均达到99.0％以上，可以作为检测对甲基苯甲醚的内标试剂，具有良好的经济性。
• COMPOUNDS FOR MODULATING HUR (ELAVL1)
  申请人：[en]SHANGHAI DEGRON BIOMEDICAL TECHNOLOGY CO., LTD.

  公开号：WO2024114639A1

  公开（公告）日：2024-06-06

  The application relates to a compound of Formula (I) or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which degrades HuR, a pharmaceutical composition comprising a compound of Formula (I), and a method of treating or preventing a disease in which HuR plays a role.
• Deuterium Isotope Effect on Bulk Heterojunction Solar Cells. Enhancement of Organic Photovoltaic Performances Using Monobenzyl Substituted Deuteriofullerene Acceptors
  作者：Shirong Lu、Tienan Jin、Takeshi Yasuda、Weili Si、Kazuaki Oniwa、Khalid A. Alamry、Samia A. Kosa、Abdullah Mohamed Asiri、Liyuan Han、Yoshinori Yamamoto

  DOI：10.1021/ol4026606

  日期：2013.11.15

  A series of novel monobenzyl-substituted deuteriofullerenes (BnDCs) were synthesized efficiently through Co-catalyzed selective monofunctionalization of C-60. Bulk heterojunction solar cells, based on poly(3-hexylthiophene) as the donor and BnDCs as the acceptors, exhibited higher photovoltaic performances as compared to the corresponding protonated BnHCs devices.