dibutyl citrate | 81024-58-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: dibutyl citrate
• 英文别名: 1,2-Dibutyl citrate；5-butoxy-3-butoxycarbonyl-3-hydroxy-5-oxopentanoic acid
• CAS: 81024-58-0；123301-46-2
• 化学式: C₁₄H₂₄O₇
• 分子量: 304.34
• InChiKey: WBKYGCZSBGEBFP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  21
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.79
• 拓扑面积：
  110
• 氢给体数：
  2
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  柠檬酸 、 正丁醇 在 tetrabutoxytitanium 作用下， 反应 4.0h， 生成 monobutyl citrate 、 tributyl citrate 、 dibutyl citrate
  参考文献：
  名称：

  Esterification of citric acid with n-butanol over zirconium sulfate supported on molecular sieves

  摘要：

  Solid acid catalysts consisting of zirconium sulfate (ZS) supported on a series of molecular sieves including HZSM-5, HMS and MCM-41 were prepared and used in the esterification of citric acid with n-butanol to produce tributyl citrate (TBC). Highly dispersed ZS was supported on 40 wt.% ZS/HMS or ZS/MCM-41. whereas HZSM-5 loaded more bulk ZS species. The ZS loading and type of support showed obvious effect on thermal stability, acidity and type of acid sites. In the esterification of citric acid, 40 wt.% ZS/HMS or ZS/MCM-41 exhibited higher catalytic activity than pure ZS or 40 wt.% ZS/HZSM-5. An investigation focused on ZS/HMS showed that Bronsted and Bronsted + Lewis acid sites acted as the active center for the esterification reaction. 40 wt.% ZS/HMS calcined at 180 degrees C obtained the highest conversion of citric acid and TBC yield. The reaction was found to obey an Eley-Rideal mechanism. (C) 2013 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molcata.2013.10.001

文献信息

• [EN] METHOD FOR THE PRODUCTION OF METHYLSUCCINIC ACID AND THE ANHYDRIDE THEREOF FROM CITRIC ACID<br/>[FR] PROCÉDÉ DE PRODUCTION D'ACIDE MÉTHYLSUCCINIQUE ET DE SON ANHYDRIDE À PARTIR D'ACIDE CITRIQUE
  申请人：UNIV LEUVEN KATH

  公开号：WO2018065475A1

  公开（公告）日：2018-04-12

  A process for the preparation of methylsuccinic acid in any form, including its salts, its mono- and diester derivatives and the anhydride thereof, which comprises reacting citric acid or a derivative thereof in decarboxylation conditions, said process comprising (i) reacting citric acid or mono- and diester derivatives thereof in a non- aqueous solvent, specifically excluding alcohols, on a metallic catalyst at a temperature between 50 to 400°C and under a partial hydrogen pressure from 0.1 to 50 bar or (ii) reacting citric acid or any salt thereof or mono-, di- and triester derivatives thereof on a metallic catalyst in solvents comprising at least 5% water, at a temperature of from 50 to 400°C under a hydrogen partial pressure from 0.1 to 400 bar

  一种制备甲基琥珀酸及其盐、单酯和二酯衍生物以及其酐的方法，包括在脱羧条件下反应柠檬酸或其衍生物，所述方法包括(i) 在非水溶剂中在金属催化剂上以50至400°C的温度和0.1至50巴的部分氢压力下反应柠檬酸或其单酯和二酯衍生物，特别排除醇；或(ii) 在含水量至少为5%的溶剂中，在50至400°C的温度下，在0.1至400巴的氢分压下反应柠檬酸或其任何盐或其单酯、二酯和三酯衍生物上。
• Shaped articles which are contact lenses or bonnets for contact lens formed from polymers of styrene type monomers
  申请人：SCHERING CORPORATION

  公开号：EP0006323A1

  公开（公告）日：1980-01-09

  The invention provides shaped articles that are contact lenses or are bonnets from which such lenses may be made. The lenses have high gas permeability. They are formed of a polymer that is obtained by polymerising at least one styrenetype monomer, optionally with at least one cross-linking monomer and optionally with other mono-olefinically unsaturated monomer. Preferably the polymerisable monomers comprise, or consist of, a styrene substituted in the ring by at least one alkyl group.

  本发明提供的异形物品是隐形眼镜，或者是可以用来制作隐形眼镜的骨架。这种镜片具有高透气性。它们是由一种聚合物形成的，这种聚合物是通过聚合至少一种苯乙烯类单体、可选地与至少一种交联单体以及可选地与其他单烯烃不饱和单体而得到的。可聚合单体最好包括或由至少一个烷基取代的苯乙烯环组成。
• Article for administration of pharmacologically-active substances
  申请人：HERCON LABORATORIES CORPORATION

  公开号：EP0251425A1

  公开（公告）日：1988-01-07

  Described is an article of manufacture useful in administration of pharmacologically-active substances, transdermally, orally or by means of subdermal implant comprising a plasticized polyvinyl chloride layer for con­tacting a patient's tissue, internally or externally, the layer containing from about 20 up to about 70% by weight of a polyvinyl chloride resin or a polyvinyl chloride-­polyvinyl acetate copolymer containing a minor proportion of vinyl acetate; from about 20-70% plasticizer composition; from about 0.5 up to 35% of a pharmacologically-active sub­stance such as isosorbide dinitrate, nicotine, clonidine, guanfacine, indomethacin, glyceryl trinitrate and prosta­glandin and optionally excipients. Also described is the novel plasticizer-polyvinyl chloride composition of matter comprising 1-dodecylhexahydro-2H-azepin-2-one and polyvinyl chloride resin taken together with a pharmacologically-active substance wherein the 1-dodecylhexahydro-2H-azepin-2-one not only acts as a plasticizer but also acts as a penetration enhancer (through tissue) for the pharmacologically-active substance.

  描述了一种用于经皮、口服或通过皮下植入给药活性物质的制造品，该制造品包括用于内部或外部接触患者组织的增塑聚氯乙烯层，该层含有按重量计约20%至约70%的聚氯乙烯树脂或含有少量醋酸乙烯的聚氯乙烯-聚醋酸乙烯共聚物；约20%至70%的增塑剂组合物；约0.5% 至 35% 的药理活性物质，如二硝酸异山梨酯、尼古丁、氯尼丁、胍法辛、吲哚美辛、三硝酸甘油酯和前列腺素，以及可选的赋形剂。还描述了新型增塑剂-聚氯乙烯物质组合物，该物质组合物由 1-十二烷基六氢-2H-氮杂卓-2-酮和聚氯乙烯树脂以及药理活性物质组成，其中 1-十二烷基六氢-2H-氮杂卓-2-酮不仅用作增塑剂，还用作药理活性物质的渗透促进剂（通过组织）。
• CUTTING OR GRINDING FLUID COMPOSITION
  申请人：IDEMITSU KOSAN COMPANY LIMITED

  公开号：EP0763590A1

  公开（公告）日：1997-03-19

  A cutting or grinding oil composition comprising (A) a base oil and (B) at least one compound selected from the group consisting of dibasic acids having 2 to 6 carbon atoms, tribasic acids having 3 to 6 carbon atoms, and ester derivatives of these acids; and a cutting or grinding oil composition comprising component (A) described above, component (B) described above, (C) a compound containing sulfur, and/or (D) at least one compound selected from the group consisting of perbasic alkali metal sulfonates and perbasic alkaline earth metal sulfonates are disclosed. By using the oil composition, increase in working efficiency, such as suppressed wear of working tools and superior precision of a finished surface, can be achieved.

  本发明公开了一种切削油或研磨油组合物，包括（A）基础油和（B）至少一种选自具有 2 至 6 个碳原子的二元酸、具有 3 至 6 个碳原子的三元酸和这些酸的酯衍生物组成的组的化合物；以及一种切削油或研磨油组合物，包括上述组分（A）、上述组分（B）、（C）含硫化合物和/或（D）至少一种选自过碱金属磺酸盐和过碱土金属磺酸盐组成的组的化合物。通过使用该油组合物，可以提高工作效率，如抑制加工工具的磨损和提高加工表面的精度。
• REMOVING SOLUTION
  申请人：Daikin Industries, Ltd.

  公开号：EP1536291A1

  公开（公告）日：2005-06-01

  The present invention provides a resist-removing solution for low-k film and a cleaning solution for via holes or capacitors, the solutions comprising hydrogen fluoride (HF) and at least one member selected from the group consisting of organic acids and organic solvents. The invention also provides a method of removing resist and a method of cleaning via holes or capacitors by the use of the solutions.

  本发明提供了一种用于低 K 薄膜的抗蚀剂去除溶液和一种用于通孔或电容器的清洁溶液，这些溶液包括氟化氢（HF）和至少一种从有机酸和有机溶剂组成的组中选出的成员。本发明还提供了一种使用这些溶液去除抗蚀剂的方法和清洗通孔或电容器的方法。