2-pentyl-decanoic acid | 60948-92-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-pentyl-decanoic acid
• 英文别名: 2-Pentyl-decansaeure；Octylpentylacetic acid；2-pentyldecanoic acid
• CAS: 60948-92-7
• 化学式: C₁₅H₃₀O₂
• 分子量: 242.402
• InChiKey: MFHYZHQSCYJZEV-UHFFFAOYSA-N

物化性质

• 沸点：
  355.5±10.0 °C(Predicted)
• 密度：
  0.894±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  17
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 生成 2-pentyl-decanoic acid
  参考文献：
  名称：

  Greer; Adams, Journal of the American Chemical Society, 1930, vol. 52, p. 2542

  摘要：

  DOI：

文献信息

• Compounds for Treating Disorders Mediated by Metabotropic Glutamate Receptor 5, and Methods of Use Thereof
  申请人：Hardy Larry Wendell

  公开号：US20110319380A1

  公开（公告）日：2011-12-29

  Provided herein are compounds and methods of synthesis thereof. The compounds set forth herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders, neurodegenerative disorders, neuropsychiatric disorders, disorders of cognition, learning or memory, gastrointestinal disorders, lower urinary tract disorder, and cancer. Compounds set forth herein modulate the activity of metabotropic glutamate receptor 5 (mGluR5) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.

  本文提供了化合物及其合成方法。本文中提供的化合物可用于治疗、预防和/或管理各种疾病，如神经系统疾病、神经退行性疾病、神经精神疾病、认知、学习或记忆障碍、胃肠道疾病、下尿路障碍和癌症。本文提供的化合物在中枢神经系统或外周调节代谢性谷氨酸受体5(mGluR5)的活性。本文还提供了含有这些化合物的药物制剂及其使用方法。
• COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF
  申请人：Sunovion Pharmaceuticals Inc.

  公开号：US20140349992A1

  公开（公告）日：2014-11-27

  Provided herein are compounds and methods of synthesis thereof. The compounds set forth herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders, neurodegenerative disorders, neuropsychiatric disorders, disorders of cognition, learning or memory, gastrointestinal disorders, lower urinary tract disorder, and cancer. Compounds set forth herein modulate the activity of metabotropic glutamate receptor 5 (mGluR5) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.

  本文提供了化合物及其合成方法。这些化合物可用于治疗、预防和/或管理各种疾病，如神经疾病、神经退行性疾病、神经精神疾病、认知、学习或记忆障碍、胃肠道疾病、下尿路障碍和癌症等。本文提供的化合物在中枢神经系统或外周调节代谢性谷氨酸受体5 (mGluR5) 的活性。本文还提供了含有这些化合物的药物制剂及其使用方法。
• Diacylglycerin and cosmetic composition
  申请人：KAO CORPORATION

  公开号：EP0391431A1

  公开（公告）日：1990-10-10

  The following diacylglycerin is useful for a cosmetic oil and a cosmetic composition such as pack, cream and emulsion. (where one each of R₁, R₂, and R₃ denotes a residue of a straight-chain saturated fatty acid having 11-17 carbon atoms, a residue of a branched-chain saturated fatty acid having 10-18 carbon atoms, and a hydrogen atom)

  以下二酰甘油可用于化妆品油和化妆品组合物，如包装、膏霜和乳液。 (其中 R₁、R₂ 和 R₃ 各表示一个具有 11-17 个碳原子的直链饱和脂肪酸残基、一个具有 10-18 个碳原子的支链饱和脂肪酸残基和一个氢原子）。
• COMPOSITION FOR PROTECTION OF BODY SURFACE
  申请人：Asahi Kasei Chemicals Corporation

  公开号：EP1891924A1

  公开（公告）日：2008-02-27

  A body surface protecting composition, comprising at least one type of multi-chain multiple hydrophilic group-type compound having two or more hydrophobic groups and two or more hydrophilic groups in the molecule, which has an excellent effect of accelerating the recovery of the barrier function of skin and hair and preventing degradation of that function.

  一种体表保护组合物，包含至少一种多链多亲水基团型化合物，其分子中含有两个或两个以上的疏水基团和两个或两个以上的亲水基团，该组合物在加速恢复皮肤和头发的屏障功能以及防止该功能退化方面具有极佳的效果。
• DISPERSION LIQUID AND HYDROGEL FORMATION METHOD
  申请人：Nissan Chemical Industries, Ltd.

  公开号：EP2865442A1

  公开（公告）日：2015-04-29

  There is provided a dispersion containing a lipid peptide type compound useful as a low molecular weight gelator, such as a lipid dipeptide and a lipid tripeptide, and a solvent capable of dissolving the lipid peptide type compound at a lower temperature more easily. There is provided also a dispersion from which a hydrogel can be formed by a simpler method and under a milder condition (low temperature) and from which a gel can be obtained as a gel having high thermal stability, and provide a method for forming the gel. A dispersion comprising a lipid peptide type compound in which a peptide portion having an amino acid repeating bonding structure is bonded to a lipid portion consisting of a C9-23 aliphatic group; and at least one alcohol selected from the group consisting of 1,2-alkanediol, 1,3-alkanediol, and ethylene glycol monoalkyl ether or a mixed solution of the at least one alcohol and water; and a method for producing a hydrogel by use of the dispersion.

  本发明提供了一种含有可用作低分子量凝胶剂的脂质肽类化合物（如脂质二肽和脂质三肽）的分散液，以及一种能够在较低温度下更容易溶解脂质肽类化合物的溶剂。本发明还提供了一种分散液，可通过更简单的方法在更温和的条件下（低温）形成水凝胶，并从中获得具有高热稳定性的凝胶，同时还提供了形成凝胶的方法。一种包含脂肽型化合物的分散液，其中具有氨基酸重复键合结构的肽部分与由 C9-23 脂肪族基团组成的脂质部分键合；以及至少一种选自 1,2-烷二醇、1,3-烷二醇和乙二醇单烷基醚或至少一种醇和水的混合溶液组成的组的醇，以及一种通过使用该分散液生产水凝胶的方法。