1,2-bis(N-benzoyl-N-methylamino)benzene | 35975-04-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,2-bis(N-benzoyl-N-methylamino)benzene
• 英文别名: o-bis(N-benzoyl-N-methyl)benzene；N,N'-dimethyl-N,N'-o-phenylene-bis-benzamide；N,N'-Dimethyl-N,N'-o-phenylen-bis-benzamid；N,N'-Dibenzoyl-N,N'-dimethyl-o-phenylendiamin；N-[2-[benzoyl(methyl)amino]phenyl]-N-methylbenzamide
• CAS: 35975-04-3
• 化学式: C₂₂H₂₀N₂O₂
• 分子量: 344.413
• InChiKey: VBUKEOAVBKATCR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  26
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  40.6
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-羟基苯并咪唑 在 吡啶 、 lithium aluminium tetrahydride 、 氯化亚砜 、 乙醚 、 水 作用下， 生成 1,2-bis(N-benzoyl-N-methylamino)benzene
  参考文献：
  名称：

  Zinner; Spangenberg, Chemische Berichte, 1958, vol. 91, p. 1432,1436

  摘要：

  DOI：

文献信息

• A chiral N-methylbenzamide: Spontaneous generation of optical activity
  作者：Isao Azumaya、Iwao Okamoto、Shingo Nakayama、Aya Tanatani、Kentaro Yamaguchi、Koichi Shudo、Hiroyuki Kagechika

  DOI：10.1016/s0040-4020(99)00647-x

  日期：1999.9

  crystals of the two enantiomers were distinguishable morphologically, and their CD spectra in KBr were mirror images. In solution, several conformational isomers due to rotations of the ArN bonds and the amide bonds were observed. The major conformer corresponds to the crystal structure in which the two N-benzoyl groups exist on opposite sides of the central benzene ring (anti conformation) and the amide

  从蒸馏的乙酸乙酯中结晶出1,2-双（N-苯甲酰基-N-甲基氨基）苯（1），作为属于空间群P 2 1 2 1 2 1的手性晶体。两种对映异构体的旋光晶体在形态上是可区分的，它们在KBr中的CD光谱是镜像的。在溶液中，观察到由于ArN键和酰胺键旋转引起的几种构象异构体。主要构象物对应于晶体结构，其中两个N-苯甲酰基存在于中心苯环的相对侧（反构象），且酰胺键均为顺式。溶液中的对映异构体可以通过在手性1,1'-联-2-萘酚存在下的1 H-NMR进行区分。从它们在MeOH中的1：1混合溶液中获得1和（R）-1,1'-bi-2-萘酚的混合晶体。X射线晶体学分析表明，混合晶体中1的构型为（R，R）。CD 2 Cl 2中的178 K下的混合晶体的1 H-NMR测量表明，CD 260 -（+）-晶体中1的绝对构型为（R，R）。
• Cellulose Compound Film, Optical Compensation Sheet, Polarizing Plate, and Liquid Crystal Display Device
  申请人：Nozoe Yutaka

  公开号：US20070259134A1

  公开（公告）日：2007-11-08

  A cellulose compound film containing a cellulose compound having two or more substituents whose polarizability anisotropies Δα calculated by mathematical formula (1) are different from each other, wherein substitution degrees of the following substituents A and B in the cellulose compound satisfy relationship as defined by mathematical formula (A1), in which the substituent A has the lowest Δα and the substituent B has the highest Δα: Δ ⁢ ⁢ α = α ⁢ ⁢ x - α ⁢ ⁢ y + α ⁢ ⁢ z 2 Mathematical ⁢ ⁢ formula ⁢ ⁢ ( 1 ) wherein, in characteristic values obtained after diagonalization of polarizability tensor, αx is the largest component, αy is the second largest component, and αz is the smallest component; DS B 2+ DS B 3− DS B 6≧−0.1   Mathematical formula (A1) wherein DS B 2, DS B 3, and DS B 6 represent a substitution degree of the substituent B at the 2-, 3-, or 6-position of a β-glucose ring constituting unit of cellulose, respectively; and an optical compensation film, a polarizing plate, and a liquid crystal display device, using the cellulose compound film.

  一种纤维素化合物薄膜，其含有具有两个或更多取代基的纤维素化合物，其极化率各向异性Δα通过数学公式（1）计算得出，其中以下取代基A和B的取代度满足数学公式（A1）所定义的关系，其中取代基A具有最低的Δα，而取代基B具有最高的Δα：Δα = αx-αy + αz2数学公式（1）其中，在极化率张量对角化后获得的特征值中，αx是最大分量，αy是第二大分量，αz是最小分量;DSB2 + DSB3-DSB6≥-0.1数学公式（A1）其中DSB2、DSB3和DSB6分别表示取代基B在纤维素构成单位β-葡萄糖环的2-、3-或6-位置的取代度;以及使用该纤维素化合物薄膜的光学补偿膜、偏光板和液晶显示装置。
• Cellulose Acylate Film, Method of Producing the Same, Cellulose Derivative Film, Optically Compensatory Film Using the Same, Optically-Compensatory Film Incorporating Polarizing Plate, Polarizing Plate and Liquid Crystal Display Device
  申请人：Haruta Hiromoto

  公开号：US20090290100A1

  公开（公告）日：2009-11-26

  A method of producing a cellulose derivative film, the method comprising: forming a film with a solvent cast method from a dope including a cellulose derivative satisfying following conditions (a) and (b): (a) at least one among three hydroxyl groups included in a glucose unit of cellulose is substituted by a substituent of which a polarizability anisotropy Δα represented as following Expression (1) is 2.5×10 −24 cm 3 or higher: Expression (1): Δα=αx−(αy+αz)/2, wherein αx, αy and αz is as defined in the specification; and (b) when a substitution degree by a substituent of which Δα is 2.5×10 −24 cm 3 or higher is P A , and a substitution degree by a substituent of which Δα is lower than 2.5×10 −24 cm 3 is P B , the P A and P B satisfy following Expressions (3) and (4): Expression (3): 2P A +P B >3.0; and Expression (4): P A >0.2.

  一种生产纤维素衍生物薄膜的方法，该方法包括：使用包括满足以下条件（a）和（b）的纤维素衍生物的溶胶，通过溶剂浇铸法形成薄膜：（a）纤维素的葡萄糖单元中的三个羟基中的至少一个被取代为极化率各向异性Δα（以下表达式（1）表示）为2.5×10-24cm3或更高的取代基：表达式（1）：Δα=αx-（αy+αz）/ 2，其中αx，αy和αz如规范中定义的；并且（b）当Δα为2.5×10-24cm3或更高的取代基的取代度为PA时，Δα低于2.5×10-24cm3的取代基的取代度为PB，PA和PB满足以下表达式（3）和（4）：表达式（3）：2PA + PB> 3.0；表达式（4）：PA> 0.2。
• Cellulose acylate film, optically compensatory film, polarizing plate and liquid crystal display
  申请人：Nishiura Yosuke

  公开号：US20070059458A1

  公开（公告）日：2007-03-15

  A cellulose acylate film is provided and satisfies the following relationships (I) and (II). The cellulose acylate film has a residual sulfuric acid content of 0 ppm to 100 ppm and contains a release accelerator in an amount of 10 ppm to 2,000 ppm. 0≦ Re (630)≦10 and | Rth (630)|≦25  (I) | Re (400)− Re (700)|≦10 and | Rth (400)− Rth (700)|≦35  (II) Re(λ) is an in-plane retardation value at a wavelength of λ nm, and Rth(λ) is a thickness-direction retardation value at a wavelength of λ nm.
• Optical film, optical compensation film, polarizing plate and liquid crystal display
  申请人：Nakayama Hajime

  公开号：US20070076155A1

  公开（公告）日：2007-04-05

  An optical film is provided and has retardations satisfying relations (1) to (3): 0≦Re(550)≦10;   (1) −25≦ Rth (550)≦25; and   (2) |I|+|II|+|III|+|IV |>0.5 (nm),   (3) with definitions: I=Re (450)− Re (550); II=Re (650)− Re (550); III=Rth (450)− Rth (550); and IV=Rth (650)− Rth (550), wherein Re(450), Re(550) and Re(650) are in-plane retardations measured with lights of wavelength of 450, 550 and 650 nm, respectively; and Rth(450), Rth(550) and Rth(650) are retardations in a thickness direction of the optical film, which are measured with lights of wavelength of 450, 550 and 650 nm, respectively.