2-丁基-2-乙基丙二酸 | 2085-15-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 2-丁基-2-乙基丙二酸
• 英文名称: Ethyl-butyl-malonsaeure
• 英文别名: Butyl-ethyl-malonsaeure；Ethyl-n-butyl-malonsaeure；ethyl-butyl-malonic acid；Aethyl-butyl-malonsaeure；2-Butyl-2-ethylmalonic acid；2-butyl-2-ethylpropanedioic acid
• CAS: 2085-15-6
• 化学式: C₉H₁₆O₄
• mdl: MFCD07780196
• 分子量: 188.224
• InChiKey: MLEXVRSHDCOQPM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.777
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 海关编码：
  2917190090

反应信息

• 作为反应物：
  描述：

  2-丁基-2-乙基丙二酸 在 五氯化磷 作用下， 生成 Butylethylmalonylchlorid
  参考文献：
  名称：

  Condensation of Substituted Malonic Esters with Diamines

  摘要：

  DOI：

  10.1021/ja01131a045
• 作为产物：
  描述：

  2-丁基-2-乙基丙二酸二乙酯 在 氢氧化钾 作用下， 生成 2-丁基-2-乙基丙二酸
  参考文献：
  名称：

  Dolique, Annales de Chimie (Cachan, France), 1931, vol. <10> 15, p. 425,505, 506

  摘要：

  DOI：

文献信息

• METHOD FOR PREPARING QUATERNARY PHOSPHONIUM SALTS
  申请人：Microvast Power Systems Co.,Ltd.

  公开号：US20150166587A1

  公开（公告）日：2015-06-18

  A two-step pathway for preparing high pure quaternary phosphonium salts is disclosed. In the first step, hydrogen phosphide (PH 3 ) or a higher phophine reacts with a protonic compound to produce a phosphonium salt, which then reacts with a carbonic acid diester to produce a quaternary phosphonium salt in the second step. On one hand, hydrogen phosphide (PH 3 ) and higher phophines, including primary phosphines, secondary phosphines, and tertiary phosphines, after neutralization with protonic compound, become sufficiently reactive and can be alkylated by carbonic acid diester to form quaternary phosphonium cations. On the other hand, as an anion-exchange procedure is completely avoided, the process not only gives quaternary phosphonium salts of high purity, but also gives people freedom to design the cation and the anion of a quaternary phosphonium salt synchronously by choosing a preferred phosphine and a protonic compound that can supply a desired anion.

  揭示了一种制备高纯度四元磷铵盐的两步途径。在第一步中，氢磷化物（PH3）或更高的磷化物与质子化合物发生反应，产生磷铵盐，然后在第二步中与碳酸二酯发生反应，产生四元磷铵盐。一方面，氢磷化物（PH3）和更高的磷化物，包括一次磷化物、二次磷化物和三次磷化物，在与质子化合物中和后变得足够活性，可以被碳酸二酯烷基化形成四元磷铵阳离子。另一方面，由于完全避免了阴离子交换程序，该过程不仅提供高纯度的四元磷铵盐，还使人们可以通过选择理想的磷化物和可以提供所需阴离子的质子化合物，同时设计四元磷铵盐的阳离子和阴离子。
• Arachidonic acid analogues
  申请人：BEECHAM GROUP PLC

  公开号：EP0207599A1

  公开（公告）日：1987-01-07

  Compounds of formula (I): or, where appropriate, a solt or amide thereof, wherein R' is hydrogen or C1-6 alkyl; R2 is hydrogen or CO2R3 where R3 is hydrogen or C1-8 alkyl; X and X' are independently a double or triple bond; A and B are hydrogen when X is a double bond or A and B are both absent when X is a triple bond; A' and B' are hydrogen when X' is a double bond or A' and B' are both absent when X' is a triple bond; n is 0 or an integer of from 1 to 4; and m is an integer of from 2 to 7; processes for preparing such compounds; pharmaceutical compositions containing such compounds and the use of such compounds and compositions in medicine.

  式(I)化合物： 或（如适用）其溶液或酰胺，其中 R' 为氢或 C1-6 烷基；R2 为氢或 CO2R3，其中 R3 为氢或 C1-8 X和X'独立地为双键或三键；当X为双键时，A和B为氢，或当X为三键时，A和B都不存在。 当 X 是三键时，A 和 B 都不存在；当 X' 是双键时，A'和 B'是氢，或当 X' 是三键时，A'和 B'都不存在； n为0或1至4的整数；m为2至7的整数；制备此类化合物的工艺；含有此类化合物的药物组合物以及此类化合物和组合物在医药中的用途。
• Process for producing quaternary salts
  申请人：MITSUBISHI PETROCHEMICAL CO., LTD.

  公开号：EP0291074A2

  公开（公告）日：1988-11-17

  A process for producing quaternary salts of high purity is disclosed, comprising reacting a tertiary amine or phosphine with a carbonic acid diester to form a correspond­ing quaternary carbonate and further mixing it with an acid to perform decarboxylation. The quaternary salts thus ob­tained are useful compounds which can be used in wide fields as various catalysts, electrolytes, additives, medicaments, etc.

  本发明公开了一种生产高纯度季盐的工艺，包括将叔胺或膦与碳酸二酯反应生成相应的季碳酸盐，并进一步与酸混合进行脱羧反应。由此获得的季盐是有用的化合物，可广泛用作各种催化剂、电解质、添加剂、药物等。
• Blocked biuretized isocyanates
  申请人：Bayer MaterialScience LLC

  公开号：EP1650244A1

  公开（公告）日：2006-04-26

  The present invention is directed to blocked biuret group-containing polyisocyanate compositions, wherein the blocking agent is selected from the group consisting of di-C1-C12-alkyl and/or alkoxyalkyl malonates and acetoacetic acid C1-C12-alkyl and/or alkoxyalkyl esters.

  本发明涉及封端含生物脲基的聚异氰酸酯组合物，其中封端剂选自二-C1-C12-烷基和/或烷氧基烷基丙二酸酯和乙酰乙酸 C1-C12- 烷基和/或烷氧基烷基酯组成的组。
• HYDROCARBYL SOLUBLE QUATERNARY AMMONIUM CARBOXYLATES AND FUEL COMPOSITIONS CONTAINING THEM
  申请人：Afton Chemical Corporation

  公开号：EP2960319A2

  公开（公告）日：2015-12-30

  A fuel additive composition, fuel composition, method of improving the injector performance of a fuel injected engine, method for preventing or cleaning up deposits in an engine or fuel system, method of reducing wear in a fuel system of an engine, and method of improving the demulsibility of a fuel composition. The fuel composition includes from about 5 to about 300 ppm by weight based on a total weight of the fuel composition of a hydrocarbyl soluble quaternary ammonium carboxylate derived from a quaternary ammonium carbonate and an organic acid.

  一种燃料添加剂组合物、燃料组合物、改善喷油发动机喷油器性能的方法、防止或清理发动机或燃料系统中沉积物的方法、减少发动机燃料系统磨损的方法以及改善燃料组合物反乳化性的方法。以燃料组合物的总重量为基准，燃料组合物包括约 5 至约 300 ppm（按重量计）的烃基可溶性季铵羧酸盐，该季铵羧酸盐由季铵碳酸盐和有机酸衍生而来。