2-丁基十二烷-1-醇 | 21078-85-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 2-丁基十二烷-1-醇
• 英文名称: 5-hydroxymethyl-pentadecane
• 英文别名: 5-Hydroxymethyl-pentadecan；2-butyl-1-dodecanol；Hydroxymethylpentadecan-5；2-Butyl-dodecan-1-ol；2-butyldodecan-1-ol
• CAS: 21078-85-3
• 化学式: C₁₆H₃₄O
• 分子量: 242.445
• InChiKey: UMKNBNWWXLQQGU-UHFFFAOYSA-N

物化性质

• 沸点：
  304.4±10.0 °C(Predicted)
• 密度：
  0.834±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7
• 重原子数：
  17
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 乙醇 、 sodium 作用下， 生成 2-丁基十二烷-1-醇
  参考文献：
  名称：

  Some Isomeric Branched Hexadecanols

  摘要：

  DOI：

  10.1021/ja01313a014

文献信息

• Substituted melatonin derivatives, process for their preparation, and methods of use
  申请人：Tao Chunlin

  公开号：US20070191463A1

  公开（公告）日：2007-08-16

  The invention provides 2 aryl substituted derivatives of melatonin. The invention further provides pharmaceutical compositions comprising such derivatives, methods for preparing such derivatives, and methods of using such derivatives to induce general anesthesia, sedation, and/or hypnotic or sleep effects in a patient, and to treat conditions affected by melatonin activity in a patient.

  这项发明提供了2种芳基取代的褪黑激素衍生物。该发明还提供了包括这些衍生物的药物组合物，制备这些衍生物的方法，以及利用这些衍生物在患者中诱导全身麻醉、镇静和/或催眠或睡眠效果，并治疗受褪黑激素活性影响的患者病况的方法。
• [EN] GUERBET CONDENSATION REACTION<br/>[FR] RÉACTION DE CONDENSATION DE GUERBET
  申请人：UNIV GENT

  公开号：WO2017093473A1

  公开（公告）日：2017-06-08

  The invention relates to a process for the preparation of a Guerbet alcohol, comprising the steps of: (a) providing at least one alcohol, wherein said at least one alcohol has a carbon atom bearing at least one hydrogen atom adjacent to the hydroxyl group; (b) providing a catalyst composition, wherein said catalyst composition comprises an alkaline catalyst and a copper-nickel catalyst comprised in a hydrotalcite; (c) mixing alcohol (a) with catalyst composition (b), thereby obtaining a mixture; and, (d) heating said mixture; thereby obtaining a Guerbet alcohol.

  这项发明涉及一种制备Guerbet醇的过程，包括以下步骤：(a)提供至少一种醇，其中所述至少一种醇具有至少一个碳原子，其上带有至少一个与羟基相邻的氢原子；(b)提供催化剂组合物，其中所述催化剂组合物包括碱性催化剂和铜-镍催化剂，其包含在水滑石中；(c)将醇(a)与催化剂组合物(b)混合，从而获得混合物；以及(d)加热所述混合物；从而获得Guerbet醇。
• PROCESS FOR DYEING HAIR
  申请人：Henkel AG & Co. KGaA

  公开号：US20200397684A1

  公开（公告）日：2020-12-24

  The subject of the present disclosure is a process for dyeing human hair, in which a pretreatment agent (A) which contains at least one organic silicon compound of the formula (I) and/or (II) and contains no direct dyes and no pigments, and a colorant (B) which contains at least one organic silicon compound of the formula (I) and/or (II) and further contains at least one colorant compound from the group of direct dyes and/or pigments, can be applied to the hair, wherein the organic silicon compounds of formulae (I) and (II) are defined as follows R 1 R 2 N-L-Si(OR 3 ) a (R 4 ) b (I), (R 5 O) c (R 6 ) d Si-(A) e -[NR 7 -(A′)] f —[O-(A″)] g -[NR 8 -(A′″)] h —Si(R 6 ′) d′ (OR 5 ′) c′ (II).

  本公开的主题是一种染色人类头发的过程，其中可以将含有至少一种有机硅化合物公式(I)和/或(II)且不含有直接染料和颜料的预处理剂(A)，和含有至少一种有机硅化合物公式(I)和/或(II)且进一步含有直接染料和/或颜料化合物群中的至少一种颜料化合物的染料剂(B)应用于头发上。其中，公式(I)和(II)的有机硅化合物定义如下：R1R2N-L-Si(OR3)a(R4)b(I)，(R5O)c(R6)dSi-(A)e-[NR7-(A′)]f—[O-(A″)]g-[NR8-(A′″)]h—Si(R6′)d′(OR5′)c′(II)。
• Ascorbic acid derivatives and skin-whitening cosmetics
  申请人：Shibayama Hiroharu

  公开号：US20060264407A1

  公开（公告）日：2006-11-23

  It is an object to provide an L-ascorbic acid derivative which can keep the L-ascorbic acid stable to heat and light and thus has a long shelf life, which is high in permeability into the skin, which can be quickly hydrolyzed by phosphatase, an enzyme that is ubiquitous in vivo, and which exhibits physiological activities that are inherent to L-ascorbic acid and beneficial to health, a method for producing such an L-ascorbic acid derivative, and a skin-whitening cosmetic material. There is provided an ascorbic acid derivative comprising an L-ascorbic acid-2-phosphate ester or a salt thereof wherein the phosphate ester has a branched alkyl group, the L-ascorbic acid-2-phosphate ester being of formula [13]. The ascorbic acid derivative is produced by a method comprising reacting a branched alkanol with phosphorus oxychloride to synthesize monoalkyldichlorophosphate or dialkylmonochlorophosphate, reacting the thus obtained substance with 5,6-O-isopropylidene-L-ascorbic acid obtained by reacting L-ascorbic acid with acetone, and subjecting the thus obtained substance to acid hydrolysis. There is also provided a cosmetic material containing such an ascorbic acid derivative by 0.05 to 80 percent by weight. (wherein each of R 1 and R 2 is a hydrogen (H) atom or an alkyl group having branches and including 3 to 30 carbon atoms, but not both of R 1 and R 2 are hydrogen (H) atoms)

  本发明旨在提供一种L-抗坏血酸衍生物，该衍生物可以使L-抗坏血酸在热和光下保持稳定性，因此具有长时间的保质期，其渗透性高，可以快速被磷酸酶水解，磷酸酶是普遍存在于体内的酶，并且具有固有于L-抗坏血酸的生理活性和有益于健康的功效，以及生产这种L-抗坏血酸衍生物的方法和美白皮肤的化妆品材料。提供一种抗坏血酸衍生物，包括L-抗坏血酸-2-磷酸酯或其盐，其中磷酸酯具有支链烷基，L-抗坏血酸-2-磷酸酯的化学式为[13]。通过将支链醇与氧化氯磷反应合成单烷基二氯磷酸酯或双烷基单氯磷酸酯，将所得物质与通过将L-抗坏血酸与丙酮反应得到的5,6-O-异丙基-L-抗坏血酸反应，并将所得物质进行酸水解制备出该抗坏血酸衍生物。还提供了一种化妆品材料，其中包含0.05至80重量百分比的抗坏血酸衍生物。（其中R1和R2中的每一个是氢（H）原子或具有分支的烷基，包括3至30个碳原子，但R1和R2中不同时存在氢（H）原子）
• Barium oxide catalyzed ethoxylation
  申请人：Conoco Inc.

  公开号：EP0006105A1

  公开（公告）日：1980-01-09

  Barium oxide is used as an ethoxylation catalyst for the reaction of ethylene oxide and alkanols of all classes. The reaction is carried out at temperatures of from about 200 to about 500° F to yield the ethoxylated product. The product abtained has a very narrow, high adduct distribution with low levels of by-products and unreacted free alcohols. Calcium and magnesium oxides show no catalytic effect.

  氧化钡可用作环氧乙烷和各类烷醇反应的乙氧基化催化剂。反应在华氏 200 度到 500 度之间进行，生成乙氧基化产物。得到的产品具有很窄的高加成分布，副产物和未反应的游离醇含量很低。钙和镁氧化物没有催化作用。