1-triphenylsilyl-2-phenyl-3,5-bis(trimethylsilyl)benzene | 1438770-18-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-triphenylsilyl-2-phenyl-3,5-bis(trimethylsilyl)benzene
• 英文别名: Trimethyl-(2-phenyl-5-trimethylsilyl-3-triphenylsilylphenyl)silane；trimethyl-(2-phenyl-5-trimethylsilyl-3-triphenylsilylphenyl)silane
• CAS: 1438770-18-3
• 化学式: C₃₆H₄₀Si₃
• 分子量: 556.97
• InChiKey: ZXSBGKNDJFYUSL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.82
• 重原子数：
  39
• 可旋转键数：
  7
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  三苯基氯硅烷 在 正丁基锂 、 palladium diacetate 、 二异丁基氢化铝 、 N,N-二异丙基乙胺 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 反应 51.5h， 生成 1-triphenylsilyl-2-phenyl-3,5-bis(trimethylsilyl)benzene
  参考文献：
  名称：

  Regioselective Synthesis of Multisubstituted Benzenes by Palladium-Catalyzed Intermolecular Reaction of β-Iodo-β-silylstyrenes with Alkynes

  摘要：

  The Pd-catalyzed reaction between beta-iodo-beta-silyistyrenes and terminal alkynes in i-Pr2NEt gave 1,2,3,5-tetrasubstituted benzenes with complete regioselection. The use of certain silylacetylenes as alkynes enabled efficient synthesis of 1,3,5-trissilyl-2-arylbenzenes, which could be transformed into other multisubstituted benzenes by displacement of the silyl groups.

  DOI：

  10.1021/ol4010883

文献信息

• Regioselective Synthesis of Multisubstituted Benzenes by Palladium-Catalyzed Intermolecular Reaction of β-Iodo-β-silylstyrenes with Alkynes
  作者：Hidenori Kinoshita、Hirotoshi Takahashi、Katsukiyo Miura

  DOI：10.1021/ol4010883

  日期：2013.6.21

  The Pd-catalyzed reaction between beta-iodo-beta-silyistyrenes and terminal alkynes in i-Pr2NEt gave 1,2,3,5-tetrasubstituted benzenes with complete regioselection. The use of certain silylacetylenes as alkynes enabled efficient synthesis of 1,3,5-trissilyl-2-arylbenzenes, which could be transformed into other multisubstituted benzenes by displacement of the silyl groups.