2-丙基-丁二烯酸 | 16776-81-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 2-丙基-丁二烯酸
• 英文名称: 2-vinylidenepentanoic acid
• 英文别名: 3-Carboxy-hexadien-(1,2)；2-propyl-butadienoic acid；2-Propyl-butadiensaeure；2-ethenylidenepentanoic acid
• CAS: 16776-81-1
• 化学式: C₇H₁₀O₂
• 分子量: 126.155
• InChiKey: CNCKSFUEBPHINL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.58
• 重原子数：
  9.0
• 可旋转键数：
  3.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  37.3
• 氢给体数：
  1.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  2-丙基-丁二烯酸 在 dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer 、 copper(II) choride dihydrate 、 癸-1,2-二烯-4-醇 作用下， 以 乙腈 为溶剂， 反应 5.0h， 以59%的产率得到4-chloro-3-propyl-2(5H)-furanone
  参考文献：
  名称：

  在 2,3- 烯丙醇存在下 Rh 催化 2,3- 烯丙酸的环化

  摘要：

  在本文中，我们报告了 [Cp*RhCl 2 ] 2催化的两种不同类型的丙二烯与 2,3-丙烯酸的偶联环化反应，提供 2(5 H )-呋喃酮骨架的产物和 2,3-丙二烯醇形成共轭 ( E )-烯醛或烯酮官能团连接到 2(5 H )-呋喃酮的 β-位。这些产品是合成潜在生物活性化合物的重要组成部分。该反应通过由铑携带的核金属化、插入和立体定义的 1,4- H传递进行。

  DOI：

  10.1039/d1cc04367f
• 作为产物：
  描述：

  1-溴-2-己炔 在 乙醚 、 magnesium 作用下， 生成 2-丙基-丁二烯酸
  参考文献：
  名称：

  The Propargylic Rearrangement. I. The Carbonation Products of Grignard Reagents from Primary Propargylic Bromides

  摘要：

  DOI：

  10.1021/ja01160a058

文献信息

• Palladium-Catalyzed Dehydrogenative Carbonylative Esterification of Allenoic Acids for the Synthesis of γ-Butyrolactone Derivatives
  作者：Bolin Wang、Mingzhe Ren、Nasir Iqbal、Xin Mu、Jan-E. Bäckvall、Bin Yang

  DOI：10.1021/acs.orglett.4c00572

  日期：2024.3.29

  A highly efficient dehydrogenative carbonylative esterification of allenoic acids using Pd-catalysis was developed, providing a novel approach to synthesizing esterified γ-butyrolactone derivatives with consistently good to excellent results demonstrated across over 50 examples. Additionally, we used a heterogeneous catalyst known as Pd-AmP-MCF and harnessed biomimetic-aerobic-oxidation conditions

  开发了一种使用 Pd 催化的联烯酸高效脱氢羰基化酯化方法，提供了一种合成酯化 γ-丁内酯衍生物的新方法，并在 50 多个实例中证明了始终如一的良好至优异的结果。此外，我们使用了一种称为 Pd-AmP-MCF 的多相催化剂，并利用仿生有氧氧化条件来促进该反应的实际执行。此外，我们对 γ-丁内酯产品的详细研究突显了它们在合成生物活性化合物方面的潜力。
• Pansard,J.; Gaudemar,M., Bulletin de la Societe Chimique de France, 1968, p. 3332 - 3336
  作者：Pansard,J.、Gaudemar,M.

  DOI：——

  日期：——
• Commercial Marine Emissions and Life-Cycle Analysis of Retrofit Controls in a Changing Science and Policy Environment
  作者：James J. Corbett、Paul S. Fischbeck

  DOI：10.1111/j.1559-3584.2002.tb00113.x

  日期：2002.1

  ABSTRACTThis paper considers the technical feasibility of achieving NOx reductions through engine controls on existing ocean‐ going ships. International transport ships account for most of the NOx emissions from shipping globally and regionally (Corbett and Fischbeck 1997; Corbett et al. 1999). Recently, regulatory efforts to control NOx from ship propulsion have been adopted at the international level (IMO 1998) along with related efforts at national levels (EPA 1998a; Lemieszewski 1999; National Swedish Maritime Administration 1996; Swedish Port and Stevedores Association 1999). The long working life of modern commercial ships, with world fleet averages greater than 20 years (UNCTAD 1995), implies that new‐engine policies have limited value in meeting air‐quality objectives in the near term. This has motivated efforts to control shipboard emissions with retrofit technologies. Nine technologies, demonstrated to control NOx from existing engines, are described in terms of their ability to reduce emissions at the lowest life‐cycle costs. The costs for these technologies are within the cost range of similar controls proposed for new marine engines and within the cost ranges for various land‐based NOx control efforts, suggesting that these are not only technically feasible but also are economically reasonable technologies for pollution control.
• Rh-Catalyzed cyclization of 2,3-allenoic acids in the presence of 2,3-allenols
  作者：Junjie Fan、Chunling Fu、Xiaoyan Wu、Shengming Ma

  DOI：10.1039/d1cc04367f

  日期：——

  Herein we report a [Cp*RhCl2]2-catalyzed coupling cyclization of two different classes of allenes with 2,3-allenoic acids affording 2(5H)-furanone skeletons of products and 2,3-allenols forming a conjugated (E)-enal or enone functionality to the β-position of the 2(5H)-furanones. These products are important building blocks for the syntheses of potentially bioactive compounds. The reaction proceeded

  在本文中，我们报告了 [Cp*RhCl 2 ] 2催化的两种不同类型的丙二烯与 2,3-丙烯酸的偶联环化反应，提供 2(5 H )-呋喃酮骨架的产物和 2,3-丙二烯醇形成共轭 ( E )-烯醛或烯酮官能团连接到 2(5 H )-呋喃酮的 β-位。这些产品是合成潜在生物活性化合物的重要组成部分。该反应通过由铑携带的核金属化、插入和立体定义的 1,4- H传递进行。
• The Propargylic Rearrangement. I. The Carbonation Products of Grignard Reagents from Primary Propargylic Bromides
  作者：John H. Wotiz

  DOI：10.1021/ja01160a058

  日期：1950.4