2-丙基氧杂环丁烷 | 4468-64-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧杂环丁烷
• 中文名称: 2-丙基氧杂环丁烷
• 英文名称: 2-propyloxetane
• 英文别名: 2-Propyl-oxetan
• CAS: 4468-64-8
• 化学式: C₆H₁₂O
• 分子量: 100.161
• InChiKey: KJPUWZVESPGSAG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  7
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-丙基氧杂环丁烷 在 吗啉 、 吡啶 、 咪唑 、 4-二甲氨基吡啶 、 ammonium molybdate 、 水 、 双氧水 、 碘 、 palladium diacetate 、 双(三甲基硅烷基)氨基钾 、 1,8-二氮杂双环[5.4.0]十一碳-7-烯 、 三乙胺 、 lithium bromide 作用下， 以 四氢呋喃 、 乙醇 、 二氯甲烷 、 水 、 N,N-二甲基甲酰胺 、 甲苯 、 乙腈 、 叔丁醇 为溶剂， 反应 175.0h， 生成
  参考文献：
  名称：

  Total Synthesis and Structural Confirmation of the Antimalarial Naphthopyrone Lasionectrin

  摘要：

  The total synthesis of lasionectrin, a naphthopyrone metabolite of an Acremonium-like fungus collected in Equatorial Guinea, is reported. Divergent access to four stereoisomers confirmed the natural product to be the enantiomer of the originally proposed structure. Highlights of the synthesis include ring opening of a chiral oxetane using a thiol, a highly E-selective Julia-Kocienski olefination, and a modified Sharpless/Upjohn dihydroxylation. Palladium-catalyzed carbonylative lactonization was used to assemble the fused naphthopyrone ring system.

  DOI：

  10.1021/acs.orglett.5b03202
• 作为产物：
  描述：

  正己烷 在 氧气 作用下， 生成 2-丙基氧杂环丁烷
  参考文献：
  名称：

  气相氧化法从碳氢化合物中提取化学物质

  摘要：

  DOI：

  10.1021/ie51394a030

文献信息

• SUBSTITUTED 4-PYRIDONES AND THEIR USE AS INHIBITORS OF NEUTROPHIL ELASTASE ACTIVITY
  申请人：OOST Thorsten

  公开号：US20140057916A1

  公开（公告）日：2014-02-27

  This invention relates to substituted 4-pyridones of formula 1 and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary, gastrointestinal and genitourinary diseases, inflammatory diseases of the skin and the eye and other auto-immune and allergic disorders, allograft rejection, and oncological diseases.

  这项发明涉及式1的取代4-吡啶酮及其作为中性粒细胞弹性蛋白酶活性抑制剂的用途，包含这些化合物的药物组合物，以及将其用作治疗和/或预防肺部、胃肠道和泌尿系统疾病、皮肤和眼睛的炎症性疾病以及其他自身免疫和过敏性疾病、移植物排斥反应和肿瘤性疾病的药剂的方法。
• SUBSTITUTED PYRAZOLES AS HERBICIDES
  申请人：E I DU PONT DE NEMOURS AND COMPANY

  公开号：US20150105252A1

  公开（公告）日：2015-04-16

  Disclosed is a method for controlling the growth of undesired vegetation comprising contacting the vegetation or its environment with a herbicidally effective amount of a compound of Formula 1, including all stereoisomers, N-oxides, and salts thereof, wherein A, R 1 , Q and J are as defined in the disclosure. Also disclosed is a method wherein the compound of Formula 1 (i.e. in a herbicidally effective amount) is comprised in a herbicidal composition further comprising at least one component selected from the group consisting of surfactants, solid diluents and liquid diluents. Also disclosed are compound of Formula 1 (including all stereoisomers), including N-oxides and salts thereof, their use as herbicides wherein A, R 1 , Q and J are as defined in the disclosure.

  揭示了一种控制不受欢迎植被生长的方法，包括使用化合物Formula 1的草甘膦有效量与植被或其环境接触，其中Formula 1中的所有立体异构体、N-氧化物和盐均包括在内，其中A、R1、Q和J如披露中所定义。还揭示了一种方法，其中Formula 1的化合物（即在草甘膦有效量中）包含在一个杀草剂组合物中，该组合物进一步包括从表面活性剂、固体稀释剂和液体稀释剂组成的群体中选择的至少一种成分。还揭示了Formula 1的化合物（包括所有立体异构体）、包括N-氧化物和盐，其用作除草剂，其中A、R1、Q和J如披露中所定义。
• Improved process for the preparation of substituted furanones
  申请人：QUANTUM CHEMICAL CORPORATION (a Virginia corp.)

  公开号：EP0348549A1

  公开（公告）日：1990-01-03

  This invention relates to an improved process for the preparation of 3-acyl-5-alkyldihydro-2(3H)-furanones according to the following reaction scheme: wherein R and R1 are hydrogen or alkyl and R2 is a hydrocarbon or -0-hydrocarbon radical of from 1 to 20 carbon atoms and X is a leaving group.

  这项发明涉及一种改进的制备3-酰基-5-烷基二氢-2(3H)-呋喃酮的过程，根据以下反应方案进行：其中R和R1为氢或烷基，R2为含有1至20个碳原子的烃或-0-烃基，X为离去基团。
• BLACK PIGMENT, METHOD FOR PRODUCING SAME, PIGMENT DISPERSION LIQUID, PHOTOSENSITIVE COMPOSITION AND CURED PRODUCT OF SAID PHOTOSENSITIVE COMPOSITION
  申请人：TORAY INDUSTRIES, INC.

  公开号：US20190218396A1

  公开（公告）日：2019-07-18

  Provided is a black pigment that enables pattern formation of pixel division layer while suppressing generation of development residue. The black pigment comprises (a) a core containing at least one organic black pigment selected from the group consisting of benzodifuranone-based black pigments, perylene-based black pigments, azo-based black pigments, and isomers thereof and (b) a coating layer containing silica and/or a metal oxide and/or a metal hydroxide.

  提供的是一种黑色颜料，可以在抑制开发残留物生成的同时，实现像素分割层的图案形成。该黑色颜料包括(a)至少含有一种有机黑色颜料的核心，所述有机黑色颜料选自苯并二呋喃酮类黑色颜料、苝类黑色颜料、偶氮类黑色颜料及其异构体等组中的一种；以及(b)包含二氧化硅和/或金属氧化物和/或金属羟化物的涂层层。
• Complex catalyst, process for producing the complex catalyst, and process for producing alchohol derivative with the complex catalyst
  申请人：——

  公开号：US20040077487A1

  公开（公告）日：2004-04-22

  There are provided (asymmetric) complex catalysts comprising metal complexes and Lewis acids as components, the metal complex being of formula (1): 1 wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and R 8 are the same or different and are independently hydrogen, halogen, alkyl or the like; one of R 9 and R 10 is hydrogen and the other is alkyl of 1 to 4 carbon atoms or the like; Q is a single bond or alkylene of 1 to 4 carbon atoms; M is a metal ion; and A is a balancing counter ion or ligand; processes for the production of these complex catalysts; processes for the production of (optically active) alcohol derivatives, characterized in that cyclic ether compounds are reacted with phenol derivatives in the presence of these complex catalysts; and further processes for producing (optically active) nitrogen-containing heterocyclic compounds by reacting these alcohol derivatives with halogenated nitrogen-containing heterocyclic compounds in the presence of a base.

  提供了由金属配合物和路易斯酸组成的（不对称的）复杂催化剂，其中金属配合物的化学式为（1）：1其中R1、R2、R3、R4、R5、R6、R7和R8相同或不同，独立地是氢、卤素、烷基或类似物；R9和R10中的一个是氢，另一个是1至4个碳原子的烷基或类似物；Q是单键或1至4个碳原子的烷基；M是金属离子；A是平衡的反离子或配体；制备这些复杂催化剂的方法；制备（光学活性的）醇衍生物的方法，其特征在于在这些复杂催化剂的存在下，环氧化合物与酚衍生物反应；以及在碱的存在下，通过将这些醇衍生物与卤素化的含氮杂环化合物反应，制备（光学活性的）含氮杂环化合物的进一步方法。