2-丙烯酸2-乙基己基酯与2-丙烯酸甲酯聚合物 | 28554-24-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 2-丙烯酸2-乙基己基酯与2-丙烯酸甲酯聚合物
• 英文名称: 2-Ethylhexyl prop-2-enoate;methyl prop-2-enoate
• CAS: 28554-24-7
• 化学式: C15H26O4
• 分子量: 270.36
• InChiKey: GLCLVABDAUAHHJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.28
• 重原子数：
  19
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• PATCH
  申请人：HISAMITSU PHARMACEUTICAL CO. INC.

  公开号：EP1847264A1

  公开（公告）日：2007-10-24

  A Bisoprolol patch, wherein the skin penetration rate of Bisoprolol after 24 hours is 15 to 60% of the maximum skin penetration rate thereof, shows a little difference between the maximum level of the concentration in blood and the minimum level thereof in repeated administration and, therefore, scarcely exhibits side effects. Moreover, it achieves the quick development of the drug effect owing to the stabilization of the concentration in blood within a short time.

  比索洛尔贴片在 24 小时后的皮肤渗透率为其最大皮肤渗透率的 15%至 60%，在重复给药时，血液中浓度的最大值与最小值之间的差异很小，因此几乎不会产生副作用。此外，由于血液中的浓度在短时间内趋于稳定，它还能迅速产生药效。
• TRANSDERMAL PATCH AND METHOD FOR AUGMENTING ADHESIVE STRENGTH THEREOF
  申请人：Hisamitsu Pharmaceutical Co., Inc.

  公开号：EP2601944A1

  公开（公告）日：2013-06-12

  A patch comprising a support and an adhesive agent layer, wherein the adhesive agent layer comprises at least one selected from the group consisting of tolterodine acetate and salts thereof.

  一种贴片，包括支架和粘合剂层，其中粘合剂层包括至少一种选自醋酸托特罗定及其盐类的物质。
• HYDROUS ADHESIVE SKIN PATCH
  申请人：NIPRO Patch Co., Ltd.

  公开号：EP2749279A1

  公开（公告）日：2014-07-02

  The purpose of the present invention is to provide a hydrous adhesive skin patch which contains lidocaine and can be applied in a uniform thickness easily. This hydrous adhesive skin patch comprises a support and an adhesive agent layer arranged on the support, wherein lidocaine or a pharmacologically acceptable salt thereof, a hydrophilic adhesive agent, and diethylene glycol or a diethylene glycol monoalkyl ether are contained in the adhesive agent layer. The diethylene glycol monoalkyl ether is preferably at least one compound selected from the group consisting of diethylene glycol monomethyl ether, diethylene glycol monoethyl ether and diethylene glycol monobutyl ether.

  本发明的目的是提供一种含利多卡因且易于均匀涂抹的水性皮肤粘合贴片。这种水合粘合皮肤贴片包括一个支架和一个布置在支架上的粘合剂层，其中粘合剂层中含有利多卡因或其药理上可接受的盐、亲水性粘合剂和二甘醇或二甘醇单烷基醚。二乙二醇单烷基醚最好是至少一种选自二乙二醇单甲醚、二乙二醇单乙醚和二乙二醇单丁醚的化合物。
• WATER-BASED ADHESIVE PATCH
  申请人：Teikoku Seiyaku Co., Ltd.

  公开号：EP3988172A1

  公开（公告）日：2022-04-27

  The purpose of the present invention is to provide an aqueous patch in which basic physical properties as an aqueous patch are less likely to deteriorate and crystals of 1-menthol are less likely to precipitate. The aqueous patch includes, in a pasty preparation, 1-menthol: 0.5% by mass or more and 10% by mass or less, an oil component: 0.2% by mass or more and 19% by mass or less; and silica: 0.1% by mass or more and 5.5% by mass or less.

  本发明的目的是提供一种水性贴剂，其作为水性贴剂的基本物理性质不易劣化，1-薄荷醇的结晶不易析出。这种水性贴剂在糊状制剂中包括 1-薄荷醇：0.5%（质量分数）或更高，10%（质量分数）或更低；油成分：0.2%（质量分数）或更高，19%（质量分数）或更低；以及二氧化硅：0.1%（质量分数）或更高，19%（质量分数）或更低：0.1%（以质量计）以上，5.5%（以质量计）以下。
• Dispersion of polymer particles in a non-aqueous medium and cosmetic use thereof
  申请人：L'OREAL

  公开号：US10973753B2

  公开（公告）日：2021-04-13

  The invention relates to a dispersion of polymer particles stabilized with a stabilizer in a nonaqueous medium containing at least one hydrocarbon-based oil, the polymer of the particles being a C1-C4 alkyl (meth)acrylate polymer; the stabilizer being a C1-C4 alkyl (meth)acrylate polymer and optionally of a silicone macromonomer (I): the stabilizer being a polymer comprising from 50% to 100% by weight, relative to the total weight of the stabilizer, of C8-C22 alkyl acrylate, from 0 to 50% by weight of C1-C4 alkyl (meth)acrylate and optionally silicone macromonomer (I). The invention also relates to the composition comprising said dispersion of polymer particles. Cosmetic use for caring for and making up keratin materials.

  本发明涉及一种在含有至少一种烃基油的非水介质中用稳定剂稳定的聚合物颗粒的分散体，颗粒的聚合物是一种 C1-C4 烷基（甲基）丙烯酸酯聚合物；稳定剂是一种 C1-C4 烷基（甲基）丙烯酸酯聚合物，也可以是有机硅大单体 (I)： 稳定剂是一种聚合物，按重量计，相对于稳定剂的总重量，由 50%至 100%的 C8-C22 丙烯酸烷基酯、0 至 50%的 C1-C4 烷基（甲基）丙烯酸酯和可选的有机硅大单体 (I)组成。 本发明还涉及由所述聚合物颗粒分散体组成的组合物。 用于护理和妆点角质材料的化妆品。