2-丙烯酸乙酯与1-乙烯基-2-吡咯烷酮的聚合物 | 25085-37-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 2-丙烯酸乙酯与1-乙烯基-2-吡咯烷酮的聚合物
• 英文名称: 1-Ethenylpyrrolidin-2-one;ethyl prop-2-enoate
• CAS: 25085-37-4
• 化学式: C11H17NO3
• 分子量: 211.26
• InChiKey: YAKZAWBQNVBQSE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.49
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  46.6
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• POLYVINYL ALCOHOL PARTICLES, PHARMACEUTICAL BINDER USING SAME, PHARMACEUTICAL TABLET, SUSTAINED-RELEASE PHARMACEUTICAL TABLET, AND METHOD FOR PRODUCING POLYVINYL ALCOHOL PARTICLES
  申请人：THE NIPPON SYNTHETIC CHEMICAL INDUSTRY CO., LTD.

  公开号：US20170209377A1

  公开（公告）日：2017-07-27

  Provided herein is a polyvinyl alcohol fine particle suitable for a pharmaceutical binder for obtaining a pharmaceutical tablet of properties including good sustained release, high hardness, and excellent friability. The polyvinyl alcohol tine particle of the present invention contains 25 mol % or more of a gauche structure in polyvinyl alcohol molecules within a 0.8-nm region inside the particle from the particle surface.

  本发明提供了一种聚乙烯醇细颗粒，适用于制备具有良好持续释放性、高硬度和优异易碎性等特性的药物片剂的药物粘合剂。本发明的聚乙烯醇细颗粒在颗粒表面内0.8纳米范围内的聚乙烯醇分子中含有25摩尔％或更多的 gauche 结构。
• Compositions comprising encapsulated material
  申请人：Ness Nicholas Jeremy

  公开号：US20060039934A1

  公开（公告）日：2006-02-23

  A composition such as a water-based consumer product comprises material (e.g. perfume) encapsulated within shell capsules, each capsule comprising an encapsulating wall having an inner surface and an outer surface, with a coating on the inner surface and/or outer surface of the shell wall, the composition further comprising surfactant and/or solvent. The coating can improve the barrier properties of the shell and can enhance retention of the encapsulated materials within the shell.

  一种水基消费品的组合物，包括封装在壳体胶囊内的材料（例如香水），每个胶囊包括具有内表面和外表面的封装壁，壳体壁的内表面和/或外表面上有涂层，组合物进一步包括表面活性剂和/或溶剂。涂层可以改善壳体的屏障性能，并可以增强封装材料在壳体内的保留能力。
• Molding resins and uv-transparent molds made therefrom
  申请人：COOK COMPOSITES AND POLYMERS

  公开号：EP0553007A1

  公开（公告）日：1993-07-28

  UV-transparent forming tools or molds are prepared from molding resins comprising a urethane acrylate, and an alpha, beta-ethylenically unsaturated monomer, cured in the presence of a peroxide initiator. The resins are tough, durable and have a wide range of other desirable properties.

  紫外线透明成型工具或模具由成型树脂制备而成，该树脂包括聚氨酯丙烯酸酯和α、β-乙烯不饱和单体，在过氧化物引发剂存在下固化。这种树脂坚韧耐用，并具有其他多种理想特性。
• Fragranced compositions comprising encapsulated material
  申请人：QUEST INTERNATIONAL B.V.

  公开号：EP1393706A1

  公开（公告）日：2004-03-03

  A fragranced composition such as a water-based consumer product comprises material (e.g. perfume) encapsulated within shell capsules, each capsule comprising an encapsulating wall having an inner surface and an outer surface, with a coating on the inner surface and/or outer surface of the shell wall, the composition further comprising surfactant and/or solvent. The coating can improve the barrier properties of the shell and can enhance retention of the encapsulated materials within the shell.

  一种香味组合物，如水基消费品，包括封装在外壳胶囊中的材料（如香水），每个胶囊包括一个具有内表面和外表面的封装壁，外壳壁的内表面和/或外表面有一层涂层，组合物还包括表面活性剂和/或溶剂。涂层可以提高外壳的阻隔性能，并能增强封装材料在外壳内的保留。
• ORALLY DISINTEGRATING TABLET
  申请人：NIPRO CORPORATION

  公开号：EP2409688A1

  公开（公告）日：2012-01-25

  It is an object to provide an orally disintegrating tablet produced by dry granulation and compression, having a hardness of 40 N or more, a disintegration time of 30 seconds or shorter, a friability of 0.1% or less, and an excellent feeling upon ingestion, that is capable of disintegrating with a small amount of water, having a rapid disintegration time, and being maintained stably in a tablet form, which could not been achieved by conventional procedures. Disclosed is an orally disintegrating tablet produced by dry granulation which contains a medicinal ingredient with silica, and sugar alcohol or/and sugar.

  本发明的目的是提供一种通过干法制粒和压片生产的口腔崩解片剂，其硬度为 40 N 或以上，崩解时间为 30 秒或更短，易碎性为 0.1% 或更低，服用时感觉良好，只需少量水即可崩解，崩解时间快，并能稳定地保持片剂形态，这是传统方法无法实现的。 本发明公开了一种通过干法制粒生产的口腔崩解片剂，其中含有一种药物成分和二氧化硅、糖醇或/和糖。