2-乙基-2-[[2-[(羟基甲氧基)甲基]-2-(羟甲基)丁氧基]甲基]丙烷-1,3-二醇 | 94248-72-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 2-乙基-2-[[2-[(羟基甲氧基)甲基]-2-(羟甲基)丁氧基]甲基]丙烷-1,3-二醇
• 中文别名: 丁二酸单异辛酯
• 英文名称: Isooctyl hydrogen succinate
• 英文别名: 4-(6-methylheptoxy)-4-oxobutanoic acid
• CAS: 94248-72-3
• 化学式: C₁₂H₂₂O₄
• 分子量: 230.3
• InChiKey: QDHAMQZZWGKACC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  16
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• COSMETICS
  申请人：SHISEIDO COMPANY, LTD.

  公开号：EP1352638A1

  公开（公告）日：2003-10-15

  The cosmetic of the present invention is a cosmetic that alleviates skin irritation by blending in polypropylene glycol, a specific polar oil, or polybutylene glycol, as well as an ultraviolet absorbent. The present invention also relates to an agent and a method for alleviating irritation by lipophilic drugs. Since the present invention alleviates skin irritation due to ultraviolet absorbents and lipophilic drugs in cosmetics, any amount of ultraviolet absorbents and lipophilic drugs can be blended in cosmetics, and therefore cosmetics that can fully manifest their effects can be provided. Also, it is possible to prepare a safe sunblock cosmetic with superior ultraviolet protection effects because the ultraviolet absorbent is not absorbed through skin.

  本发明的化妆品是一种通过混合聚丙二醇、特定极性油或聚丁二醇以及紫外线吸收剂来减轻皮肤刺激的化妆品。本发明还涉及一种减轻亲脂性药物刺激的制剂和方法。由于本发明可减轻化妆品中紫外线吸收剂和亲脂药物对皮肤的刺激，因此可在化妆品中混合任意量的紫外线吸收剂和亲脂药物，从而提供可充分体现其效果的化妆品。此外，由于紫外线吸收剂不会被皮肤吸收，因此可以制备出具有卓越紫外线防护效果的安全防晒化妆品。
• Cosmetics
  申请人：——

  公开号：US20030185772A1

  公开（公告）日：2003-10-02

  The cosmetic of the present invention is a cosmetic that alleviates skin irritation by blending in polypropylene glycol, a specific polar oil, or polybutylene glycol, as well as an ultraviolet absorbent. The present invention also relates to an agent and a method for alleviating irritation by lipophilic drugs. Since the present invention alleviates skin irritation due to ultraviolet absorbents and lipophilic drugs in cosmetics, any amount of ultraviolet absorbents and lipophilic drugs can be blended in cosmetics, and therefore cosmetics that can fully manifest their effects can be provided. Also, it is possible to prepare a safe sunblock cosmetic with superior ultraviolet protection effects because the ultraviolet absorbent is not absorbed through skin.

  本发明的化妆品是一种通过混合聚丙二醇、特定极性油或聚丁二醇以及紫外线吸收剂来减轻皮肤刺激的化妆品。本发明还涉及一种减轻亲脂性药物刺激的制剂和方法。由于本发明可减轻化妆品中紫外线吸收剂和亲脂药物对皮肤的刺激，因此可在化妆品中混合任意量的紫外线吸收剂和亲脂药物，从而提供可充分体现其效果的化妆品。此外，由于紫外线吸收剂不会被皮肤吸收，因此可以制备出具有卓越紫外线防护效果的安全防晒化妆品。
• COSMETICS FOR ALLEVIATING SKIN IRRITATION
  申请人：SHISEIDO COMPANY, LTD.

  公开号：EP1352638B1

  公开（公告）日：2009-05-20
• US7169379B2
  申请人：——

  公开号：US7169379B2

  公开（公告）日：2007-01-30