cis-Tetrahydro-2,5-furandiessigsaeure | 51250-33-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: cis-Tetrahydro-2,5-furandiessigsaeure
• 英文别名: 2,2'-((2R,5S)-tetrahydrofuran-2,5-diyl)diacetic acid；2-[(2S,5R)-5-(carboxymethyl)oxolan-2-yl]acetic acid
• CAS: 51250-33-0
• 化学式: C₈H₁₂O₅
• 分子量: 188.18
• InChiKey: CVYAVSIMBYOCGA-OLQVQODUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  83.8
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  cis-Tetrahydro-2,5-furandiessigsaeure-dimethylester 、 氢氧化钾 生成 cis-Tetrahydro-2,5-furandiessigsaeure
  参考文献：
  名称：

  RAU, O.;KERN, W.;SPITELLER, G., LIEBIGS ANN. CHEM., 1984, N 8, 1504-1512

  摘要：

  DOI：

文献信息

• [EN] SYNTHESIS OF DIACIDS, DIALDEHYDES, OR DIAMINES FROM THF-DIOLS<br/>[FR] SYNTHÈSE DE DIACIDES, DE DIALDÉHYDES OU DE DIAMINES À PARTIR DE TÉTRAHYDROFURANE-DIOLS
  申请人：ARCHER DANIELS MIDLAND CO

  公开号：WO2015057365A3

  公开（公告）日：2015-06-11
• Rau, Oskar; Spiteller, Gerhard; Boecker, Ronald, Liebigs Annalen der Chemie, 1984, # 8, p. 1513 - 1518
  作者：Rau, Oskar、Spiteller, Gerhard、Boecker, Ronald

  DOI：——

  日期：——
• SYNTHESIS OF DIACIDS, DIALDEHYDES, OR DIAMINES FROM THF-DIOLS
  申请人：Archer Daniels Midland Company

  公开号：EP3057946A2

  公开（公告）日：2016-08-24
• Synthesis of Diacids, Dialdehydes, or Diamines from THF-Diols
  申请人：ARCHER DANIELS MIDLAND COMPANY

  公开号：US20160207894A1

  公开（公告）日：2016-07-21

  A simple and elegant chemical process for the synthesis of oxygenated products, such as acids and aldehydes, or other derivative products, such as amines and nitriles, of cyclic bifunctional molecules made from renewable, bio-based sources such as HMF and/or its reduction product, 2,5-bis(hydroxymethyl)-tetrahydrofuran (bHMTHF) is described. In general, the process involves: a) generating a tetrahydrofuran-2,5-diyl-bis(methylene)-bis(sulfonate) from bHMTHFs using a sulfonate; b) displacing nucleophilically at least a sulfonate leaving group from the tetrahydrofuran-2,5-diyl-bis(methylene)-bis(sulfonate) to form a THF-dinitrile; and either c) oxidizing the THF-dinitrile with an acid having a pKa of ≦0 to generate a di-acid, or d) reducing partially the THF-dinitrile to generate a di-aldehyde, or e) reducing fully the THF-dinitrile to generate a di-amine.
• RAU, O.;KERN, W.;SPITELLER, G., LIEBIGS ANN. CHEM., 1984, N 8, 1504-1512
  作者：RAU, O.、KERN, W.、SPITELLER, G.

  DOI：——

  日期：——