2-(2-bromo-ethoxy)-benzoic acid | 99542-03-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(2-bromo-ethoxy)-benzoic acid
• 英文别名: 2-(β-Brom-aethoxy)-benzoesaeure；2-(2-Brom-aethoxy)-benzoesaeure；2-Bromoethyloxybenzoic acid；2-(2-bromoethoxy)benzoic acid
• CAS: 99542-03-7
• 化学式: C₉H₉BrO₃
• 分子量: 245.073
• InChiKey: PYAXBACITOQDMT-UHFFFAOYSA-N

物化性质

• 沸点：
  363.5±22.0 °C(Predicted)
• 密度：
  1.574±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-(2-bromo-ethoxy)-benzoic acid 在 potassium hydrogencarbonate 、 silver tetrafluoroborate 作用下， 以 二甲基亚砜 为溶剂， 反应 5.5h， 以70%的产率得到2,3-二氢-5H-1,4-苯并二氧蒎-5-酮
  参考文献：
  名称：

  羧酸银促进的内酯化：适用于制备中型和大型内酯而无需高稀释或缓慢添加的通用方法

  摘要：

  对于有机内酯而言，有效且适用的宏观内酯化方法以及充足的起始原料和简单的操作方法仍然是一项艰巨的任务。我们为中型和大型内酯开发了“新鲜人可以做”的实验方案，而不依赖于高稀释或慢速添加技术。该方法用于天然内酯或潜在药物化合物的合成对于有机化学家和药剂师可能是有用的。

  DOI：

  10.1016/j.tet.2013.07.064
• 作为产物：
  描述：

  1-(2-溴乙氧基)-2-甲基苯 在 potassium permanganate 作用下， 生成 2-(2-bromo-ethoxy)-benzoic acid
  参考文献：
  名称：

  DE213593

  摘要：

  公开号：

文献信息

• DIBENZOCYCLOHEPTATONE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS
  申请人：Laufer Stefan

  公开号：US20120115862A1

  公开（公告）日：2012-05-10

  The present invention relates to compounds of the formula I wherein R1, R2, R3, R4, X and Y have the meanings given in the description. The compounds have an action which is immunomodulating and inhibits or regulates the release of IL-1β and/or TNF-α. They can therefore be used for treatment of diseases connected with a disturbance in the immune system.

  本发明涉及公式I中的化合物，其中R1、R2、R3、R4、X和Y的含义如描述中所述。这些化合物具有免疫调节作用，并抑制或调节IL-1β和/或TNF-α的释放。因此，它们可以用于治疗与免疫系统紊乱有关的疾病。
• PROCESS FOR PRODUCING A LIQUID CRYSTAL CELL SUBSTRATE HAVING A TFT DRIVER ELEMENT, A LIQUID CRYSTAL CELL SUBSTRATE, AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：Kaneko Wakahiko

  公开号：US20090286340A1

  公开（公告）日：2009-11-19

  A process for easy production of a liquid crystal cell substrate having a TFT driver element which contributes to reducing viewing angle dependence of color of a liquid crystal display device is provided: a process using a transfer material, more preferably, a process which comprises the following steps [1] to [4] in this order: [1] transferring on a TFT substrate a transfer material having a photosensitive polymer layer and an optically anisotropic layer on a temporary support; [2] separating the temporary support from the transfer material on the TFT substrate; [3] subjecting the transfer material to light exposure on the TFT substrate; and [4] removing unnecessary parts of the photosensitive polymer layer and the optically anisotropic layer on the substrate.

  提供一种易于生产具有TFT驱动器元件的液晶电池基板的工艺，该元件有助于减少液晶显示器的颜色视角依赖性：使用传输材料的工艺，更好的是，按照以下步骤[1]至[4]的顺序进行的工艺：[1]在TFT基板上转移具有光敏聚合物层和光学各向异性层的传输材料，该传输材料位于临时支撑上；[2]从TFT基板上分离传输材料的临时支撑；[3]对TFT基板上的传输材料进行光曝光；[4]去除基板上不必要的光敏聚合物层和光学各向异性层的部分。
• TRANSFER MATERIAL, PROCESS FOR PRODUCING A COLOR FILTER USING THE SAME, A COLOR FILTER AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：Amimori Ichiro

  公开号：US20090290102A1

  公开（公告）日：2009-11-26

  A transfer material comprising at least one optically anisotropic layer and at least one photosensitive polymer layer on at least one support, wherein said optically anisotropic layer comprises one or more compounds having a reactive group, and said photosensitive polymer layer comprises two or more types of photopolymerization initiators having different photoreaction mechanisms to each other, and a compound having a reactive group which can react with one or more of the reactive groups present in the optically anisotropic layer by the action of the at least one of said photopolymerization initiators. By using the transfer material, a color filter which contributes to reducing viewing angle dependence of color of a liquid crystal display device, and a liquid crystal display device having less corner non-uniformities and less viewing angle dependence of color.

  一种转移材料，包括至少一层光学各向异性层和至少一层光敏聚合物层，位于至少一支撑体上。其中，所述光学各向异性层包括一种或多种具有反应基团的化合物，所述光敏聚合物层包括两种或更多种具有不同光反应机理的光聚合引发剂和一种具有反应基团的化合物，该反应基团可以通过至少一种所述光聚合引发剂的作用与光学各向异性层中存在的一种或多种反应基团反应。通过使用该转移材料，可以制备对液晶显示器颜色视角依赖性有所减少的彩色滤光片和液晶显示器，且具有更少的角落非均匀性和更少的颜色视角依赖性。
• Process for producing a liquid crystal cell substrate having a TFT driver element, a liquid crystal cell substrate, and liquid crystal display device
  申请人：FUJIFILM Corporation

  公开号：US07879634B2

  公开（公告）日：2011-02-01

  A process for easy production of a liquid crystal cell substrate having a TFT driver element which contributes to reducing viewing angle dependence of color of a liquid crystal display device is provided: a process using a transfer material, more preferably, a process which comprises the following steps [1] to [4] in this order: [1] transferring on a TFT substrate a transfer material having a photosensitive polymer layer and an optically anisotropic layer on a temporary support; [2] separating the temporary support from the transfer material on the TFT substrate; [3] subjecting the transfer material to light exposure on the TFT substrate; and [4] removing unnecessary parts of the photosensitive polymer layer and the optically anisotropic layer on the substrate.

  提供一种易于生产液晶显示器细胞衬底的方法，该方法具有TFT驱动元件，有助于减少液晶显示器颜色的视角依赖性：使用转移材料的方法，更好的是，按照以下步骤[1]到[4]的顺序进行的方法：[1]在TFT衬底上转移具有光敏聚合物层和光学各向异性层的转移材料；[2]将临时支撑从TFT衬底上的转移材料分离；[3]将转移材料暴露于TFT衬底上的光照下；[4]去除衬底上不必要的光敏聚合物层和光学各向异性层的部分。
• Transfer material, process for producing a color filter using the same, a color filter and liquid crystal display device
  申请人：FUJIFILM Corporation

  公开号：US08189138B2

  公开（公告）日：2012-05-29

  A transfer material comprising at least one optically anisotropic layer and at least one photosensitive polymer layer on at least one support, wherein said optically anisotropic layer comprises one or more compounds having a reactive group, and said photosensitive polymer layer comprises two or more types of photopolymerization initiators having different photoreaction mechanisms to each other, and a compound having a reactive group which can react with one or more of the reactive groups present in the optically anisotropic layer by the action of the at least one of said photopolymerization initiators. By using the transfer material, a color filter which contributes to reducing viewing angle dependence of color of a liquid crystal display device, and a liquid crystal display device having less corner non-uniformities and less viewing angle dependence of color.

  一种转移材料，包括至少一层光学各向异性层和至少一层光敏聚合物层，在至少一支撑体上，其中所述光学各向异性层包括一种或多种具有反应基团的化合物，所述光敏聚合物层包括两种或更多具有不同光反应机理的光聚合引发剂类型，以及一种具有反应基团的化合物，该化合物可以通过至少一种所述光聚合引发剂的作用与所述光学各向异性层中存在的一种或多种反应基团反应。通过使用该转移材料，可以得到对液晶显示器的颜色观看角度依赖性有所减少的彩色滤光片，以及具有更少角落不均匀性和更少颜色观看角度依赖性的液晶显示器。