Malonsaeure-methyl-(2-methylbutyl)-ester | 51251-35-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Malonsaeure-methyl-(2-methylbutyl)-ester
• 英文别名: 1-O-methyl 3-O-(2-methylbutyl) propanedioate
• CAS: 51251-35-5
• 化学式: C₉H₁₆O₄
• 分子量: 188.224
• InChiKey: CROUZHBRYLBODC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  13
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2-甲基丁醇 、 甲基丙二酸氢 在 N,N'-二环己基碳二亚胺 作用下， 生成 Malonsaeure-methyl-(2-methylbutyl)-ester
  参考文献：
  名称：

  Ledon,H. et al., Bulletin de la Societe Chimique de France, 1973, p. 2071 - 2076

  摘要：

  DOI：

文献信息

• POLYOL-BASED POLYMERS
  申请人：Bruggeman Joost P.

  公开号：US20110008277A1

  公开（公告）日：2011-01-13

  The present invention provides inventive polyol-based polymers, materials, pharmaceutical compositions, and methods of making and using the inventive polymers and materials. In certain aspects of the invention, an inventive polymer corresponds to a polymer depicted below. Exemplary inventive polymers includes those prepared using polyol units (e.g., xylitol, mannitol, sorbitol, or maltitol) condensed with polycarboxylic acid units (e.g., citric acid, glutaric acid, or sebacic acid). The inventive polymers may be further derivatized or modified. For example, the polymer may be made photocrosslinkable by adding methacrylate moieties to the polymer.
• DESIGN OF A CONDUIT FOR PERIPHERAL NERVE REPLACEMENT
  申请人：WAKE FOREST UNIVERSITY HEALTH SCIENCES

  公开号：US20150032137A1

  公开（公告）日：2015-01-29

  A biphasic material and devices comprising the same are provided for the development of conductive conduits that may be used for the treatment of peripheral nerve injury. These devices or conduits are designed such that repeated electric field gradients can be initiated to promote neurite and axonal outgrowth. Conducting conduits using doped synthetic and/or natural polymers create specifically patterned high and low conducting segmented materials, which are mechanically used to produce the electrical properties needed for nerve conduits. These electrical properties stimulate neurite outgrowth and axonal repair following a peripheral nerve transection.
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  公开号：US7060818B2

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  申请人：——

  公开号：US9675358B2

  公开（公告）日：2017-06-13