p-Butoxythiophenol | 1129-79-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯硫酚类
• 英文名称: p-Butoxythiophenol
• 英文别名: 4-Butyloxy-thiophenol；4-Butoxybenzenethiol
• CAS: 1129-79-9
• 化学式: C₁₀H₁₄OS
• mdl: MFCD12026154
• 分子量: 182.287
• InChiKey: NTVBSXKGESYRLC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  10.2
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 海关编码：
  2930909090

反应信息

• 作为反应物：
  描述：

  p-Butoxythiophenol 在 氢氧化钾 、 copper(l) chloride 作用下， 以 1,4-二氧六环 、 乙醇 为溶剂， 反应 4.0h， 生成 1-[4-(4-Butoxyphenyl)sulfanylbut-2-ynyl]-4-methyl-piperazine
  参考文献：
  名称：

  Synthesis and antifungal activity of some alkynylthio compounds

  摘要：

  Some 4-(p-alkoxyphenylthio)but-2-yn-yl-amine hydrochlorides and 4-(p-alkoxyphenylthio)prop-1-yn-yl-iodides were prepared and tested for their antifungal activity. All the tested compounds were active in inhibiting the growth of 4 fungal types. The iodine compounds were the more effective.

  DOI：

  10.1016/0223-5234(92)90118-k
• 作为产物：
  描述：

  丁氧基苯 生成 p-Butoxythiophenol
  参考文献：
  名称：

  Protiva,M. et al., Collection of Czechoslovak Chemical Communications, 1964, vol. 29, p. 2161 - 2181

  摘要：

  DOI：

文献信息

• A convenient synthesis of bis(O-arylmercaptophenyl)sulfides
  作者：Kyongtae Kim、Jo Rim Han

  DOI：10.1016/s0040-4039(00)97918-8

  日期：——

  Reactions of 5-arylthianthrenium perchlorates with arylthiolates in tetrahydrofuran at ambient temperature under nitrogen atmosphere afforded bis(o-arylmercaptophenyl)sulfides in excellent yields.

  在室温下，在氮气氛下，在四氢呋喃中使5-芳基噻吨高氯酸盐与芳基硫醇盐反应，以优异的产率得到双（邻芳基巯基苯基）硫化物。
• Electrochemically Catalyzed Newman–Kwart Rearrangement: Mechanism, Structure–Reactivity Relationship, and Parallels to Photoredox Catalysis
  作者：Arend F. Roesel、Mihkel Ugandi、Nguyen Thi Thu Huyen、Michal Májek、Timo Broese、Michael Roemelt、Robert Francke

  DOI：10.1021/acs.joc.0c00831

  日期：2020.6.19

  new developments, a better understanding of the underlying principles is crucial. In this context, we have studied the Newman–Kwart rearrangement of O-arylthiocarbamates to the corresponding S-aryl derivatives, the key step in the synthesis of thiophenols from the corresponding phenols. This transformation is a particularly useful example because the conventional method requires temperatures up to 300 °C

  通过空穴和电子的电化学注入促进氧化还原中性反应，也被称为“电化学催化”，是一种探索很少的方法，它有可能极大地扩大电合成的范围。为了系统地改善现有协议并为新的发展铺平道路，更好地理解基本原理至关重要。在这种情况下，我们研究了O-芳基硫代氨基甲酸酯的纽曼-科沃特重排成相应的S-芳基衍生物，是从相应的酚合成硫酚的关键步骤。这种转变是一个特别有用的例子，因为常规方法需要高达300°C的温度，而电化学催化则促进了室温下的反应。实验-量子化学相结合的方法揭示了几个反应通道，并解释了结构与反应性之间的关系。此外，还显示了快速循环伏安法测量可如何用作预测特定基材可行性的工具。该研究还揭示了与光氧化还原催化反应截然不同的相似之处，其中背电子转移和链传播是竞争途径。
• Novel sulfonyldiazomethanes, photoacid generations, resist compositions, and patterning process
  申请人：——

  公开号：US20030180653A1

  公开（公告）日：2003-09-25

  A chemical amplification type resist composition contains as a photoacid generator a sulfonyldiazomethane compound of formula (1) wherein R is H or C 1-4 alkyl or alkoxy, G is SO 2 or CO, R 3 is C 1-10 alkyl or C 6-14 aryl, p is 1 or 2, q is 0 or 1, p+q=2, n is 0 or 1, m is 3 to 11, and k is 0 to 4. The composition is suited for microfabrication, especially by deep UV lithography because of many advantages including improved resolution and improved pattern profile after development. 1

  一种化学放大型光刻胶组合物包含一种化学放大型光酸发生剂，其化学式为（1），其中R为H或C1-4烷基或烷氧基，G为SO2或CO，R3为C1-10烷基或C6-14芳基，p为1或2，q为0或1，p+q=2，n为0或1，m为3至11，k为0至4。该组合物适用于微细加工，尤其是通过深紫外光刻技术，因为具有许多优点，包括提高分辨率和在显影后改善图案轮廓。
• Uracil derivatives. IV. Growth-inhibitory activity against L-1210 cells of orotic acid derivatives and synthesis of 1-(.BETA.-D-ribofuranosyl)furo(3,4-d)pyrimidine-2,4,7(1H,3H,5H)-trione.
  作者：JUTARO OKADA、KOICHI NAKANO、HIROSHI MIYAKE

  DOI：10.1248/cpb.31.3074

  日期：——

  5-(Substituted thiomethyl)-6-carbamoyluracils (IIIb-h) and 5-(substituted thiomethyl)-uracils (Va-h) were prepared and their ability to inhibit the growth of L-1210 cells in vitro was examined. The reaction of silylated furo [3, 4-d] pyrimidine-2, 4, 7 (1H, 3H, 5H)-trione (VI) with 1-O-acetyl-2, 3, 5-tri-O-benzoyl-β-D-ribofuranose (VII) in acetonitrile in the presence of SnCl4 gave 1-(2, 3, 5-tri-O-benzoyl-β-D-ribofuranosyl) furo [3, 4-d] pyrimidine-2, 4, 7 (1H, 3H, 5H)-trione (VIII) in 81.0% yield. The protected nucleoside (VIII) was hydrolyzed by sodium methoxide to give the N1-nucleoside (X).

  5-(取代硫甲基)-6-氨基尿嘧啶衍生物 (IIIb-h) 和 5-(取代硫甲基)-尿嘧啶衍生物 (Va-h) 被合成，并测试了它们在体外抑制 L-1210 细胞生长的能力。硅化的呋喃 [3, 4-d] 嘧啶-2, 4, 7 (1H, 3H, 5H)-三酮 (VI) 与 1-O-acetyl-2, 3, 5-tri-O-benzoyl-β-D-核糖 (VII) 在氯化锡 (SnCl4) 存在下于乙腈中反应，得到了1-(2, 3, 5-tri-O-benzoyl-β-D-核糖苷)呋喃[3, 4-d] 嘧啶-2, 4, 7 (1H, 3H, 5H)-三酮 (VIII)，产率为81.0%。该保护核苷 (VIII) 经甲基钠水解后得到 N1-核苷 (X)。
• Isotopically labeled compositions and method
  申请人：Schmidt Jurgen G.

  公开号：US20080311666A1

  公开（公告）日：2008-12-18

  Compounds having stable isotopes 13 C and/or 2 H were synthesized from precursor compositions having solid phase supports or affinity tags.

  由具有稳定同位素13C和/或2H的化合物从具有固相支持或亲和标签的前体组合物中合成。