2-acetoxy-2-ethyl-acetoacetic acid ethyl ester | 99974-64-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 酮酸及其衍生物
• 英文名称: 2-acetoxy-2-ethyl-acetoacetic acid ethyl ester
• 英文别名: 2-Acetoxy-2-aethyl-acetessigsaeure-aethylester；Ethyl 2-acetyloxy-2-ethyl-3-oxobutanoate
• CAS: 99974-64-8
• 化学式: C₁₀H₁₆O₅
• 分子量: 216.234
• InChiKey: LEVQSEWMGFPEOG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  15
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  69.7
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2-acetoxy-2-ethyl-acetoacetic acid ethyl ester 生成 2-acetoxy-2-ethyl-3-semicarbazono-butyric acid ethyl ester
  参考文献：
  名称：

  酵母提取物的酶促合成L-异亮氨酸。

  摘要：

  DOI：

  10.1016/0006-3002(59)90050-2
• 作为产物：
  描述：

  2-乙基乙酰乙酸乙酯 在 lead(IV) acetate 、 苯 作用下， 生成 2-acetoxy-2-ethyl-acetoacetic acid ethyl ester
  参考文献：
  名称：

  酵母提取物的酶促合成L-异亮氨酸。

  摘要：

  DOI：

  10.1016/0006-3002(59)90050-2

文献信息

• YEAST MICROORGANISMS WITH REDUCED BY-PRODUCT ACCUMULATION FOR IMPROVED PRODUCTION OF FUELS, CHEMICALS, AND AMINO ACIDS
  申请人：GEVO, Inc.

  公开号：EP2534240A2

  公开（公告）日：2012-12-19
• Modified alcohol dehydrogenases for the production of fuels and chemicals
  申请人：Bastian Sabine

  公开号：US20110201072A1

  公开（公告）日：2011-08-18

  The present invention relates to recombinant microorganisms comprising biosynthetic pathways and methods of using said recombinant microorganisms to produce various beneficial metabolites. In various aspects of the invention, the recombinant microorganisms may further comprise one or more modifications resulting in the reduction or elimination of 3 keto-acid (e.g., acetolactate and 2-aceto-2-hydroxybutyrate) and/or aldehyde-derived by-products. In various embodiments described herein, the recombinant microorganisms may be microorganisms of the Saccharomyces clade, Crabtree-negative yeast microorganisms, Crabtree-positive yeast microorganisms, post-WGD (whole genome duplication) yeast microorganisms, pre-WGD (whole genome duplication) yeast microorganisms, and non-fermenting yeast microorganisms.
• Reduced by-product accumulation for improved production of isobutanol
  申请人：Hawkins Andrew

  公开号：US20110236942A1

  公开（公告）日：2011-09-29

  The present invention relates to recombinant microorganisms comprising biosynthetic pathways and methods of using said recombinant microorganisms to produce various beneficial metabolites. In various aspects of the invention, the recombinant microorganisms may further comprise one or more modifications resulting in the reduction or elimination of 3 keto-acid (e.g., acetolactate and 2-aceto-2-hydroxybutyrate) and/or aldehyde-derived by-products. In various embodiments described herein, the recombinant microorganisms may be microorganisms of the Saccharomyces clade, Crabtree-negative yeast microorganisms, Crabtree-positive yeast microorganisms, post-WGD (whole genome duplication) yeast microorganisms, pre-WGD (whole genome duplication) yeast microorganisms, and non-fermenting yeast microorganisms.
• Yeast microorganisms with reduced by-product accumulation for improved production of fuels, chemicals, and amino acids
  申请人：Buelter Thomas

  公开号：US20110201090A1

  公开（公告）日：2011-08-18

  The present invention relates to recombinant microorganisms comprising biosynthetic pathways and methods of using said recombinant microorganisms to produce various beneficial metabolites. In various aspects of the invention, the recombinant microorganisms may further comprise one or more modifications resulting in the reduction or elimination of 3 keto-acid (e.g., acetolactate and 2-aceto-2-hydroxybutyrate) and/or aldehyde-derived by-products. In various embodiments described herein, the recombinant microorganisms may be microorganisms of the Saccharomyces clade, Crabtree-negative yeast microorganisms, Crabtree-positive yeast microorganisms, post-WGD (whole genome duplication) yeast microorganisms, pre-WGD (whole genome duplication) yeast microorganisms, and non-fermenting yeast microorganisms.
• MODIFIED ALCOHOL DEHYDROGENASES FOR THE PRODUCTION OF FUELS AND CHEMICALS
  申请人：BASTIAN Sabine

  公开号：US20140017748A1

  公开（公告）日：2014-01-16

  The present invention relates to recombinant microorganisms comprising biosynthetic pathways and methods of using said recombinant microorganisms to produce various beneficial metabolites. In various aspects of the invention, the recombinant microorganisms may further comprise one or more modifications resulting in the reduction or elimination of 3 keto-acid (e.g., acetolactate and 2-aceto-2-hydroxybutyrate) and/or aldehyde-derived by-products. In various embodiments described herein, the recombinant microorganisms may be microorganisms of the Saccharomyces clade, Crabtree-negative yeast microorganisms, Crabtree-positive yeast microorganisms, post-WGD (whole genome duplication) yeast microorganisms, pre-WGD (whole genome duplication) yeast microorganisms, and non-fermenting yeast microorganisms.