2-叔丁基-3-氯甲基-4,6-二甲基苯酚 | 23500-79-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2-叔丁基-3-氯甲基-4,6-二甲基苯酚
• 中文别名: 1,5-二甲基-3-叔丁基-2-羟基氯化苄；3-(氯甲基)-6-(1,1-二甲基乙基)2,4-二甲基苯酚
• 英文名称: 6-(tert-butyl)-3-(chloromethyl)-2,4-dimethylphenol
• 英文别名: 2,6-di-methyl-4-tert-butyl-3-hydroxybenzyl chloride；6-Tert-butyl-3-(chloromethyl)-2,4-dimethylphenol
• CAS: 23500-79-0
• 化学式: C₁₃H₁₉ClO
• 分子量: 226.746
• InChiKey: WODZSHMAILHEGD-UHFFFAOYSA-N

物化性质

• 沸点：
  312.9±37.0 °C(Predicted)
• 密度：
  1.055±0.06 g/cm3(Predicted)
• 物理描述：
  Liquid

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

安全信息

• 海关编码：
  2908199090

反应信息

• 作为反应物：
  描述：

  2-叔丁基-3-氯甲基-4,6-二甲基苯酚 在 硫化氢 、 三乙胺 作用下， 以 甲苯 为溶剂， 生成 3,3'-dihydroxy-4,4'-di-tert-butyl-2,2',6,6'-tetramethyldibenzylsulfide
  参考文献：
  名称：

  Phenols and use thereof as stabilizers

  摘要：

  本发明涉及含有多个芳香核且这些核的桥接位于OH基团的间位的酚类化合物。这些酚具有式I的结构，##STR1## 或 ##STR2## 其中R1、R2、R3、R4、A和n如权利要求1中所定义。新型的酚类化合物非常适合用作有机聚合物和润滑油的稳定剂，并具有特别优良的颜色特性。

  公开号：

  US04507420A1
• 作为产物：
  描述：

  4-tert-butyl-3-hydroxy-2,6-dimethylbenzyl alcohol 在 氯化亚砜 、 三乙胺 作用下， 以 甲苯 为溶剂， 以67%的产率得到2-叔丁基-3-氯甲基-4,6-二甲基苯酚
  参考文献：
  名称：

  一种抗氧剂1790的合成方法

  摘要：

  本发明公开了一种抗氧剂1790的合成方法，属于化工领域，以解决现有方法存在的污染大，原料利用率低，成本高的问题。其分为三步进行，第一步是一种4‑叔丁基‑3‑羟基‑2,6‑二甲基苄醇的制备，2,4‑二甲基‑6叔丁基苯酚、浓盐酸和多聚甲醛在40℃下搅拌回流50h得到4‑叔丁基‑3‑羟基‑2,6‑二甲基苄醇，产物无需纯化处理；第二步是4‑叔丁基‑3‑羟基‑2,6‑二甲基苄氯的制备，4‑叔丁基‑3‑羟基‑2,6‑二甲基苄醇的羟基被氯化亚砜氯代得到4‑叔丁基‑3‑羟基‑2,6‑二甲基苄氯，产物可用甲苯和甲醇结晶得到，结晶后的母液脱去溶剂后可继续作为原料使用；第三步是1790产物的制备。该路线有效的降低了生产成本，步骤简单易操作，并且产生的废水较少，易于工业化生产。

  公开号：

  CN106699678A

文献信息

• 2,4,6-Trialkyl L-3-hydroxyphenylalkanoates
  申请人：Ciba-Geigy Corporation

  公开号：US03988363A1

  公开（公告）日：1976-10-26

  Ester and amides having the formula ##SPC1## Wherein R, R.sup.1 and R.sup.2 are independently lower alkyl or cycloalkyl groups, R.sup.3 is hydrogen, alkyl, cycloalkyl, alkylene, phenyl, phenyl substituted by alkyl groups, alkylthioethyl, thiobis-alkylene, alkyleneoxyalkylene, polyoxyalkylene or a polyvalent cyclic or acyclic hydrocarbon radical, R.sup.4 is hydrogen, lower alkyl, cycloalkyl, R.sup.5 is hydrogen, alkyl, phenyl, phenyl substituted by alkyl groups, alkylene, a polyvalent cyclic or acyclic hydrocarbon radical or alkyleneoxyalkylene, A is lower alkylene, m is 1 to 4 and n is 1 to 6. The esters are prepared by usual esterification procedures from a suitable alcohol and an acid of the formula III ##SPC2## or an acid halide or acid anhydride thereof. The higher alkyl esters can also be prepared from the lower alkyl ester, especially the methyl ester, by transesterification with a higher alkanol or polyol. The amides are prepared by usual amidation procedures by reacting a carboxylic acid of formula III, an acid chloride, anhydride or a lower alkyl ester thereof with the appropriate amine. The nitriles corresponding to acids of formula III are prepared as well as some malonate esters derived having the formula V. ##SPC3## The compounds are useful as stabilizers or organic materials, especially polyolefins, which deteriorate upon exposure to light and heat.

  酯和酰胺的化学式为##SPC1##其中R、R.sup.1和R.sup.2分别是独立的低烷基或环烷基基团，R.sup.3是氢、烷基、环烷基、烷基烯、苯基、烷基硫乙基、硫代双烷基、烷基氧基烷基、聚氧基烷基或多价环烷基或非环烷基烃基，R.sup.4是氢、低烷基、环烷基，R.sup.5是氢、烷基、苯基、烷基苯基、烷基烯、多价环烷基或非环烷基烃基或烷基氧基烷基，A是低烷基烯，m为1到4，n为1到6。酯通过常规酯化程序从适当的醇和化学式III的酸或其酸卤或酸酐制备而成。高烷基酯也可通过与较高烷醇或聚醇的酯交换反应，特别是与低烷基酯，尤其是甲酯进行制备。酰胺通过常规酰胺化程序，通过将化学式III的羧酸、酸氯、酸酐或其低烷基酯与适当的胺反应制备而成。相应于化学式III的酸的腈也被制备，以及一些具有化学式V的马隆酸酯衍生物。这些化合物可用作稳定剂或有机材料，特别是在光照和热力作用下会退化的聚烯烃的稳定剂。
• Phenyl ether-substituted hydroxyphenyl triazine ultraviolet light absorbers
  申请人：——

  公开号：US20030146412A1

  公开（公告）日：2003-08-07

  This invention relates generally to phenyl ether substituted triazines compounds and compositions containing same and their use to protect against degradation by environmental forces. A method for stabilizing a material by incorporating such triazines is also disclosed.

  这项发明通常涉及苯醚取代的三嗪化合物和含有这些化合物的组合物，以及它们用于抵抗环境力量降解的用途。还公开了一种通过将这些三嗪化合物纳入来稳定材料的方法。
• 2,4,6-Trialkyl-3-hydroxyphenylalkane phosphonates and phosphinates
  申请人：Ciba-Geigy Corporation

  公开号：US03962376A1

  公开（公告）日：1976-06-08

  The compounds are trialkylsubstituted hydroxyphenylalkanephosphinates and phosphonates having the formula ##SPC1## Wherein R, R.sup.1 and R.sup.2 are independently lower alkyl or cycloalkyl groups, R.sup.3 is alkyl, alkyl substituted with one halogen atom, phenyl, phenyl substituted with alkyl groups, alkoxy, alkoxy substituted with one halogen groups, phenoxy, phenoxy substituted with alkyl groups, alkylthioethoxy, alkyloxalkylenoxy, R.sup.4 is alkyl, alkyll substituted with one halogen atom, cycloalkyl, phenyl, phenyl substituted with alkyl groups, alkylthioethyl, thiobisalkylene, alkylene, polyvalent cyclic or acyclic hydrocarbon radical, A is lower alkylene and n is 1 to 4. These compounds are usually prepared by reacting the trialkylsubstituted hydroxybenzyl or hydroxyphenylalkyl halide with the appropriate trialkyl or triaryl phosphite or appropriate substituted phosphinite. The compounds are useful as stabilizers of organic materials subject to oxidative, thermal and UV light deterioration.

  这些化合物是三烷基取代的羟基苯基烷基膦酸酯和膦酸酯，其化学式为##SPC1##其中R、R.sup.1和R.sup.2分别是独立的较低烷基或环烷基基团，R.sup.3是烷基、烷基上取代一个卤素原子、苯基、苯基上取代烷基基团、烷氧基、烷氧基上取代一个卤素基团、苯氧基、苯氧基上取代烷基基团、烷硫醚氧基、烷氧基烷氧基、R.sup.4是烷基、烷基上取代一个卤素原子、环烷基、苯基、苯基上取代烷基基团、烷硫乙基、硫代双亚烷基、亚烷基、多价环烷基或非环烷基烃基，A是较低烷基，n为1至4。这些化合物通常是通过将三烷基取代的羟基苯基或羟基苯基烷基卤化物与适当的三烷基或三芳基膦酸酯或适当取代的膦酸酯反应制备的。这些化合物可用作有机材料的稳定剂，可抵抗氧化、热降解和紫外光降解。
• Dual purpose stabilizer compounds and polymer compositions containing
  申请人：The B. F. Goodrich Company

  公开号：US04163008A1

  公开（公告）日：1979-07-31

  Diesters of partially hindered mercaptophenols and 3,5-di-alkyl-4-hydroxybenzoic acid and its corresponding acid salt, wherein such diester corresponds to the following formula ##STR1## wherein R and R.sub.1 are the same and are selected from among the following ##STR2## with R.sub.6 and R.sub.7 being an aliphatic hydrocarbon radical of 3 to 10 carbon atoms; and y being 0-5; R.sub.2 is a tertiary aliphatic hydrocarbon radical having from 4 to 10 carbon atoms or an alicyclic hydrocarbon radical having from 4 to 10 carbon atoms, where the carbon atom of attachment to the aromatic ring is fully substituted; R.sub.3 is hydrogen, halogen, an aliphatic hydrocarbon radical having from 1 to 10 carbon atoms or an alicyclic hydrocarbon radical having from 3 to 10 carbon atoms; and R.sub.4 and R.sub.5 is ##STR3## where WHERE A and A' are independently selected from among hydrogen, an aliphatic hydrocarbon radical of 1 to 10 carbon atoms or an alicyclic hydrocarbon radical of 3 to 10 carbon atoms. The above diesters are highly effective stabilizers of polyolefins against oxidative degradation and also impart a modest degree of protection and such materials against UV degradation.

  部分受阻巯基酚和3,5-二烷基-4-羟基苯甲酸及其相应的酸盐的二酯，其中该二酯对应于以下公式##STR1##其中R和R.sub.1相同，从以下选取##STR2##其中R.sub.6和R.sub.7是碳原子数为3至10的脂肪烃基；y为0-5；R.sub.2为具有4至10个碳原子的三级脂肪烃基或具有4至10个碳原子的脂环烃基，芳香环的连接碳原子被完全取代；R.sub.3为氢、卤素、具有1至10个碳原子的脂肪烃基或具有3至10个碳原子的脂环烃基；R.sub.4和R.sub.5为##STR3##其中A和A'独立选择自氢、碳原子数为1至10的脂肪烃基或碳原子数为3至10的脂环烃基。上述二酯对聚烯烃具有高效的抗氧化降解稳定剂作用，并且还在一定程度上保护这些材料免受紫外线降解的影响。
• Thioether substituted phenols and their use as stabilizers
  申请人：Ciba-Geigy Corporation

  公开号：US04820756A1

  公开（公告）日：1989-04-11

  Novel compounds of the formula I ##STR1## in which R.sub.1, R.sub.2, R.sub.8, R.sub.9 and R.sub.10 are independently alkyl, alkenyl, cycloalkyl, phenyl, naphthyl, alkylphenyl or aralkyl and R.sub.1 and R.sub.2 may also be independently hydrogen or alkoxycarbonylmethyl, are described. The novel phenols are suitable as stabilizers in organic polymers and lubricants.

  本发明提供了一种公式I的新化合物##STR1##其中R.sub.1，R.sub.2，R.sub.8，R.sub.9和R.sub.10独立地表示烷基，烯基，环烷基，苯基，萘基，烷基苯基或芳基烷基，而R.sub.1和R.sub.2也可以独立地表示氢或烷氧羰基甲基。这些新的酚类化合物适用于有机聚合物和润滑剂中的稳定剂。