1-propyl-1λ4-benzo[1,3,2]dithiazole 3,3-dioxide | 1274906-12-5

• 分子结构分类: 有机化合物 - 苯类化合物
• 英文名称: 1-propyl-1λ4-benzo[1,3,2]dithiazole 3,3-dioxide
• 英文别名: 9-Propyl-7lambda6,9lambda4-dithia-8-azabicyclo[4.3.0]nona-1,3,5,8-tetraene 7,7-dioxide；9-propyl-7λ6,9λ4-dithia-8-azabicyclo[4.3.0]nona-1,3,5,8-tetraene 7,7-dioxide
• CAS: 1274906-12-5
• 化学式: C₉H₁₁NO₂S₂
• 分子量: 229.324
• InChiKey: SKIWHJJVAPZEHA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  74.1
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  邻氯苯磺酰胺 在 溴 、 potassium hydroxide 、 sodium hydroxide 作用下， 以 甲醇 、 水 、 N,N-二甲基甲酰胺 为溶剂， 反应 0.5h， 生成 1-propyl-1λ4-benzo[1,3,2]dithiazole 3,3-dioxide
  参考文献：
  名称：

  Gold-Catalyzed Nitrene Transfer to Activated Alkynes: Formation of α,β-Unsaturated Amidines

  摘要：

  A gold-catalyzed intermolecular nitrene transfer to alkynes was developed for the first time, revealing a new mode of nitrene transfer and providing a novel access to versatile alpha-imino metal carbenes. Various mild nitrene-transfer reagents were examined, and iminopyridium ylides especially those based on 3,5-dichloropyridine proved be highly effective. With activated alkynes such as N-alkynyloxazolidinones as substrates, alpha,beta-unsaturated amidines were formed in mostly good yields.

  DOI：

  10.1021/ol2002607

文献信息

• Gold-Catalyzed Nitrene Transfer to Activated Alkynes: Formation of α,β-Unsaturated Amidines
  作者：Chaoqun Li、Liming Zhang

  DOI：10.1021/ol2002607

  日期：2011.4.1

  A gold-catalyzed intermolecular nitrene transfer to alkynes was developed for the first time, revealing a new mode of nitrene transfer and providing a novel access to versatile alpha-imino metal carbenes. Various mild nitrene-transfer reagents were examined, and iminopyridium ylides especially those based on 3,5-dichloropyridine proved be highly effective. With activated alkynes such as N-alkynyloxazolidinones as substrates, alpha,beta-unsaturated amidines were formed in mostly good yields.