5-fluorohexanoic acid | 1393366-23-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 5-fluorohexanoic acid
• 英文别名: 5-Fluorocaproic acid
• CAS: 1393366-23-8
• 化学式: C₆H₁₁FO₂
• 分子量: 134.151
• InChiKey: IIGXIABVOFYNFO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  5-己烯酸 在 sodium tetrahydroborate 、 iron(III) oxalate hexahydrate 、 Selectfluor 作用下， 以 水 、 乙腈 为溶剂， 反应 0.53h， 以73%的产率得到5-fluorohexanoic acid
  参考文献：
  名称：

  Fe(III)/NaBH4 介导的未活化烯烃自由基氢氟化

  摘要：

  公开了一种强大的 Fe(III)/NaBH(4) 介导的未活化烯烃的自由基氢氟化反应，使用 Selectflor 试剂作为氟源，并导致排他性马尔可夫尼科夫加成。与传统且难以控制的烯烃自由基氢氟化反应相比，Fe(III)/NaBH(4) 介导的反应是在极其温和的反应条件下进行的（0 °C，5 分钟，CH(3)CN/H(2 ）O）。该反应可以在空气中并以水作为共溶剂进行，并表现出出色的底物范围和官能团耐受性。

  DOI：

  10.1021/ja3063716

文献信息

• Process for producing organic compound epoxy resin composition, cured article obtained from the epoxy resin, and semiconductor device obtained with epoxy resin
  申请人：——

  公开号：US20040260039A1

  公开（公告）日：2004-12-23

  There are disclosed a process for producing an organic compound in the presence of a particular substituted triarylphosphine compound, particularly, a process for producing an oxyalkylene derivative at a high yield using the above compound which is very active and easy to handle, by reacting an organic epoxy compound with a carboxylic acid ester, a carboxylic acid anhydride, a sulfonic acid ester or a carbonic acid ester, and an epoxy resin composition using a particular substituted triarylphosphine compound as a curing accelerator, a cured material of the composition and a semiconductor device using the composition.

  本文披露了一种在特定取代三芳基膦化合物存在下生产有机化合物的工艺，特别是一种使用上述化合物作为催化剂，通过将有机环氧化合物与羧酸酯、羧酸酐、磺酸酯或碳酸酯反应，以及使用特定取代三芳基膦化合物作为固化促进剂的环氧树脂组合物的工艺，从而高产地生产氧代烷基衍生物，还包括该组合物的固化材料和使用该组合物的半导体器件。
• A process for preparing oxyalkylene derivatives in the presence of phosphine oxides
  申请人：MITSUI CHEMICALS, INC.

  公开号：EP0950649B1

  公开（公告）日：2003-03-26
• COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE
  申请人：Flagship Pioneering Innovations V, Inc.

  公开号：US20210289794A1

  公开（公告）日：2021-09-23

  The invention comprises methods for decreasing colonization by a bacterium of a gut of a stink bug, the method comprising providing a composition comprising vanillin or an analog thereof; and delivering said composition to an egg from which the stink bug will hatch, whereby colonization by the bacterium within the gut of the stink bug hatched from the egg treated with the composition is decreased relative to a stink bug hatched from an untreated egg. In some embodiments, the decrease in colonization by the bacterium decreases the fitness of the stink bug, e.g., decreases reproductive ability, survival, rate of development, number of eggs, number of hatched eggs, adult emergence rate, body length, body width, body mass, or cuticle thickness. In some embodiments of the methods herein, the bacterial colonization-disrupting agent is an inhibitor of bacterial metabolism. In some embodiments, the bacterial colonization-disrupting agent is a polyhydroxyalkanoate (PHA) synthesis inhibitor.
• US6130346A
  申请人：——

  公开号：US6130346A

  公开（公告）日：2000-10-10