Capsianoside I | 121924-04-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Capsianoside I
• 英文别名: (2E,6E,10E)-14-[4,5-dihydroxy-6-(hydroxymethyl)-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-4-hydroxy-2,6,10,14-tetramethylhexadeca-2,6,10,15-tetraenoic acid
• CAS: 121924-04-7
• 化学式: C₃₂H₅₂O₁₄
• 分子量: 660.7
• InChiKey: ISQUNAAALVXWGI-DFTZOVBQSA-N

物化性质

• 物理描述：
  Solid

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  46
• 可旋转键数：
  17
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.72
• 拓扑面积：
  236
• 氢给体数：
  9
• 氢受体数：
  14

文献信息

• Therapeutic compositions and methods of treatment with capsianoside-type compounds
  申请人：BMB Patent Holding Corporation

  公开号：US10195224B2

  公开（公告）日：2019-02-05

  The present invention discloses the use of certain compounds as therapeutic agents, and in particular as analgesics and anti-inflammatory agents. Such compounds include, for example, certain diterpene monoglycosides and diterpene diglycosides. The compounds of the present invention may be synthesized or isolated from the fruit of the genus Capsicum, and in particular may be isolated from sweet bell peppers (C. annuum). Pharmaceutically-acceptable salts, enantiomers, diasteriomers, racemic mixtures, enantomerically-enriched mixtures, solvates, and prodrug s of such compounds are also disclosed. Pharmaceutical compositions and methods of using such compounds, including pharmaceutical compositions and methods of using such compounds in combination with one or more active ingredients, are also disclosed.

  本发明公开了某些化合物作为治疗剂，特别是镇痛剂和消炎剂的用途。这些化合物包括例如某些二萜单糖苷和二萜二糖苷。本发明的化合物可以从辣椒属的果实中合成或分离出来，特别是从甜椒（C. annuum）中分离出来。本发明还公开了此类化合物的药学上可接受的盐、对映体、双对映体、外消旋混合物、对映体富集混合物、溶剂和原药。此外，还公开了使用此类化合物的药物组合物和方法，包括将此类化合物与一种或多种活性成分结合使用的药物组合物和方法。