2-(2-bromo-1-methyl-2-phenylethyl)malononitrile | 191531-10-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(2-bromo-1-methyl-2-phenylethyl)malononitrile
• 英文别名: (1-Bromo-1-phenylpropan-2-yl)propanedinitrile；2-(1-bromo-1-phenylpropan-2-yl)propanedinitrile
• CAS: 191531-10-9
• 化学式: C₁₂H₁₁BrN₂
• 分子量: 263.137
• InChiKey: AEQFWDLHKJAYNJ-UHFFFAOYSA-N

物化性质

• 沸点：
  380.7±42.0 °C(Predicted)
• 密度：
  1.386±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  47.6
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1-丙烯基苯 、 2-溴丙二腈 在 偶氮二甲氧基异庚腈 作用下， 以 二氯甲烷 为溶剂， 反应 72.0h， 以68%的产率得到2-(2-bromo-1-methyl-2-phenylethyl)malononitrile
  参考文献：
  名称：

  Practical Radical Additions under Mild Conditions Using 2,2‘-Azobis(2,4-dimethyl-4-methoxyvaleronitrile) [V-70] as an Initiator

  摘要：

  Radical addition reactions of bromomalononitrile to various alkenes using 2,2'-azobis(2,4-dimethyl-4-methoxyvaleronitrile) (V-70) were examined. The advantages of V-70 which is an effective radical initiator at low temperature in contrast to the other azobis compounds are described, Especially V-70L (the low melting point diastereomer) was found to be the best radical initiator.

  DOI：

  10.1021/op970059z

文献信息

• Additions of malononitrile radicals to alkenes under mild conditions using 2,2′-azobis-(2,4-dimethyl-4-methoxyvaleronitrile) (V-70) as an initiator
  作者：Yasuyuki Kita、Atsunori Sano、Takahiro Yamaguchi、Masahisa Oka、Kentoku Gotanda、Masato Matsugi

  DOI：10.1016/s0040-4039(97)00700-4

  日期：1997.5

  The attributes of 2,2′-azobis-(2,4-dimethyl-4-methoxyvaleronitrile) (V-70), which is an effective radical initiator at low temperature, in contrast to 2,2′-azobisisobutyronitrile (AIBN) are described.

  与2,2'-偶氮二异丁腈（AIBN）相反，在低温下是有效的自由基引发剂的2,2'-偶氮二-（2,4-二甲基-4-甲氧基戊腈）（V-70）具有描述。
• Practical Radical Additions under Mild Conditions Using 2,2‘-Azobis(2,4-dimethyl-4-methoxyvaleronitrile) [V-70] as an Initiator
  作者：Yasuyuki Kita、Kentoku Gotanda、Kenji Murata、Miki Suemura、Atsunori Sano、Takahiro Yamaguchi、Masahisa Oka、Masato Matsugi

  DOI：10.1021/op970059z

  日期：1998.7.1

  Radical addition reactions of bromomalononitrile to various alkenes using 2,2'-azobis(2,4-dimethyl-4-methoxyvaleronitrile) (V-70) were examined. The advantages of V-70 which is an effective radical initiator at low temperature in contrast to the other azobis compounds are described, Especially V-70L (the low melting point diastereomer) was found to be the best radical initiator.