5,6-benzo-4-diphenylphosphoryl-2-phenyl-1,3-dioxa-2-boracyclohexane | 141521-50-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5,6-benzo-4-diphenylphosphoryl-2-phenyl-1,3-dioxa-2-boracyclohexane
• 英文别名: 4-diphenylphosphoryl-2-phenyl-5,6-benzo-1,3,2-dioxaborinane；Phosphine oxide, diphenyl(2-phenyl-4H-1,3,2-benzodioxaborin-4-yl)-；4-diphenylphosphoryl-2-phenyl-4H-1,3,2-benzodioxaborinine
• CAS: 141521-50-8
• 化学式: C₂₅H₂₀BO₃P
• 分子量: 410.217
• InChiKey: RPJNSFJPCYAODL-UHFFFAOYSA-N

物化性质

• 沸点：
  517.5±60.0 °C(Predicted)
• 密度：
  1.25±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  30
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  5,6-benzo-4-diphenylphosphoryl-2-phenyl-1,3-dioxa-2-boracyclohexane 在 pyridine 作用下， 以 吡啶 为溶剂， 以56%的产率得到5,6-benzo-4-diphenylphosphoryl-2-phenyl-2-pyridyl-1,3-dioxa-2-boracyclohexane
  参考文献：
  名称：

  Dioxaborinanes with an exocyclic phosphino group

  摘要：

  The reaction of diphenylphosphine with o-hydroxy aromatic aldehydes and a diphenylboric acid ester in the presence of tertiary amines gave ammonium 5,6-benzo- and 5,6-naphtho-4-diphenylphosphoryl-2,2-diphenyl-1,3-dioxa-2-boratacyclohexanes. The borylation of (alpha,2-dihydroxybenzyl)diphenylphosphine, generated in situ, with isobutyl phenylborate gave 5,6-benzo-4-diphenylphosphino-2-phenyl-1,3-dioza-2-boracyclohexane, which, in contrast to 1,3,2,5-dioxaboraphosphorinanes, has a high reactivity with respect: to electrophilic and nucleophilic reagents and adds oxygen, sulfur, selenium, and pyridine to give the corresponding derivatives.

  DOI：

  10.1007/bf00863936
• 作为产物：
  描述：

  diisobutyl phenylborate 、 水杨醛 、 二苯基膦 以 苯 为溶剂， 以38%的产率得到5,6-benzo-4-diphenylphosphino-2-phenyl-1,3-dioxa-2-boracyclohexane
  参考文献：
  名称：

  Dioxaborinanes with an exocyclic phosphino group

  摘要：

  The reaction of diphenylphosphine with o-hydroxy aromatic aldehydes and a diphenylboric acid ester in the presence of tertiary amines gave ammonium 5,6-benzo- and 5,6-naphtho-4-diphenylphosphoryl-2,2-diphenyl-1,3-dioxa-2-boratacyclohexanes. The borylation of (alpha,2-dihydroxybenzyl)diphenylphosphine, generated in situ, with isobutyl phenylborate gave 5,6-benzo-4-diphenylphosphino-2-phenyl-1,3-dioza-2-boracyclohexane, which, in contrast to 1,3,2,5-dioxaboraphosphorinanes, has a high reactivity with respect: to electrophilic and nucleophilic reagents and adds oxygen, sulfur, selenium, and pyridine to give the corresponding derivatives.

  DOI：

  10.1007/bf00863936

文献信息

• Musina; Balueva; Nikonov, Russian Journal of General Chemistry, 1997, vol. 67, # 3, p. 349 - 358
  作者：Musina、Balueva、Nikonov、Starikova、Yanovskii、Musin

  DOI：——

  日期：——
• Dioxaborinanes with an exocyclic phosphino group
  作者：A. S. Balueva、S. R. Prokhorova、G. N. Nikonov

  DOI：10.1007/bf00863936

  日期：1992.1

  The reaction of diphenylphosphine with o-hydroxy aromatic aldehydes and a diphenylboric acid ester in the presence of tertiary amines gave ammonium 5,6-benzo- and 5,6-naphtho-4-diphenylphosphoryl-2,2-diphenyl-1,3-dioxa-2-boratacyclohexanes. The borylation of (alpha,2-dihydroxybenzyl)diphenylphosphine, generated in situ, with isobutyl phenylborate gave 5,6-benzo-4-diphenylphosphino-2-phenyl-1,3-dioza-2-boracyclohexane, which, in contrast to 1,3,2,5-dioxaboraphosphorinanes, has a high reactivity with respect: to electrophilic and nucleophilic reagents and adds oxygen, sulfur, selenium, and pyridine to give the corresponding derivatives.