bis(2,2,2-trifluoroethyl)difluoroformal | 1801-09-8

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氟化物
• 英文名称: bis(2,2,2-trifluoroethyl)difluoroformal
• 英文别名: 1,1,1,4,4,7,7,7-octafluoro-3,5-dioxaheptane；Difluor-bis-<2,2,2-trifluor-aethoxy>-methan；2-[Difluoro(2,2,2-trifluoroethoxy)methoxy]-1,1,1-trifluoroethane
• CAS: 1801-09-8
• 化学式: C₅H₄F₈O₂
• 分子量: 248.073
• InChiKey: KGPNTXUAWKQSNS-UHFFFAOYSA-N

物化性质

• 沸点：
  81-82 °C(Press: 750 Torr)
• 密度：
  1.480±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  10

反应信息

• 作为反应物：
  描述：

  bis(2,2,2-trifluoroethyl)difluoroformal 在 五氟化锑 作用下， 生成 bis(2,2,2-trifluoroethoxy)fluoromethyl cation
  参考文献：
  名称：

  First examples of stable polyfluorinated bis- and tris-(alkoxy)methyl cations

  摘要：

  Stable polyfluorinated bis- and tris-(alkoxy)methyl cations were prepared by the reaction of the corresponding difluoroformals (RfO)(2)CF2 (R-f = -CH2CF3, -CH(CF3)(2), -CH2CF2Cl) with an excess of SbF5. Although the cation (CF3CH2O)(2)CF+ (1a) is stable at ambient temperature, the chlorinated analog (ClCF2CH2O)(2)CF+ (3a) can be generated only at low temperature in SO2ClF solvent and rapidly decomposes at ambient temperature. Although the salt [(CF3)(2)CHO](2)CF+SbnF5n+1- (2a) is slightly more stable than the salt of cation 3a, at ambient temperature it undergoes rapid disproportionation with formation of equal amounts of [(CF3)(2)CHO](3)C+SbnF5n+1- (2b) and CF3OCH(CF3)(2) (2c). Stable solid salt 2b (n = 2) 2b (n = 2) was isolated and fully characterized by H-1, F-19 and C-13 NMR spectroscopy and its structure was confirmed by single crystal X-ray diffraction. (C) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jfluchem.2005.10.001
• 作为产物：
  描述：

  二(2,2,2-三氟乙基)碳酸酯 在 sulfur tetrafluoride 、 氢氟酸 作用下， 生成 bis(2,2,2-trifluoroethyl)difluoroformal
  参考文献：
  名称：

  α-Fluorinated Ethers. II. Alkyl Fluoroalkyl Ethers¹

  摘要：

  DOI：

  10.1021/jo01024a002

文献信息

• Synthesis of fluorinated tertiary diamines and diazanes
  作者：Nimesh R. Patel、Robert L. Kirchmeier、Jean'ne M. Shreeve

  DOI：10.1016/s0022-1139(00)80224-9

  日期：1990.7

  A variety of fluorinated and partially fluorinated tertiary diamines and diazanes have been prepared from 1-[bis(trifluoromethyl)amtno]tetrafluoro-2- azapropene, which is obtained from the dimerization of 2-azapropene in the presence of CsF. Addition of ClF results in the formation of the tertiary diamine (CF3)2NCF2N(Cl)CF3. Insertion of alkenes and nitriles into the nitrogenchlorine bond, as well

  已经由1- [双（三氟甲基）氨基]四氟-2-氮杂丙烯制备了各种氟化和部分氟化的叔二胺和二氮杂，它们是在CsF存在下由2-氮杂丙烯的二聚作用获得的。ClF的添加导致叔二胺（CF 3）2 NCF 2 N（Cl）CF 3的形成。烯烃和腈插入氮-氯键中以及与SF 5 Cl和CF 3 C（O）Cl发生光解反应很容易发生。尝试制备包含来自多氟烷亚胺，例如，R基团多氟烷diazanes ˚F NC（OR ˚F '）2（R ˚FCF 3，SF 5 ; ř ˚F 'CH 2 CF 3，CH（CF 3）2）导致与的ClF亚胺的反应的carbonnitrogen双键断裂生成R ˚F的NCI 2和F 2 C（OR ˚F '）2。类似地（CF 3）2 NC（OCH 2 CF 3）NCF 3用的ClF给出CF 3的NCI 2和（CF 3）2 NCF 2 OCH 2 CF 3。
• Dihalogenoformals
  作者：L. T. Eremenko、G. V. Oreshko、M. A. Fadeev

  DOI：10.1007/bf00953710

  日期：1989.1
• A new method for the substitution of sulfur by halogen atoms in the thionocarbonate group
  作者：L. T. Eremenko、G. V. Oreshko、M. A. Fadeev

  DOI：10.1007/bf00953379

  日期：1986.11
• EREMENKO, L. T.;ORESHKO, G. V.;FADEEV, M. A., IZV. AN CCCP. CEP. XIM.,(1989) N 1, S. 113-116
  作者：EREMENKO, L. T.、ORESHKO, G. V.、FADEEV, M. A.

  DOI：——

  日期：——
• α-Fluorinated Ethers. II. Alkyl Fluoroalkyl Ethers¹
  作者：P. E. Aldrich、William A. Sheppard

  DOI：10.1021/jo01024a002

  日期：1964.1