2-Methoxy-3-methyl-6-prop-2-enylphenol | 1001324-80-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2-Methoxy-3-methyl-6-prop-2-enylphenol
• 英文别名: 2-methoxy-3-methyl-6-prop-2-enylphenol
• CAS: 1001324-80-6
• 化学式: C₁₁H₁₄O₂
• 分子量: 178.231
• InChiKey: MNNQQLCHLBZSSL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-Methoxy-3-methyl-6-prop-2-enylphenol 在 RuCl2(1,3-dimesityl-imidazolidin-2-yl)(PCy3)(=CHPh) 、 palladium 10% on activated carbon 、 氢气 、 氧气 、 copper diacetate 、 三溴化硼 作用下， 以 甲醇 、 二氯甲烷 、 甲苯 、 乙腈 为溶剂， 反应 34.0h， 生成 7-methyl-chroman-8-ol
  参考文献：
  名称：

  [EN] BICYCLIC QUINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS
  [FR] QUINONES BICYCLIQUES, COMPOSITIONS PHARMACEUTIQUES ET APPLICATIONS THÉRAPEUTIQUES

  摘要：

  Provided herein are bicyclic quinones,e.g., a compound of Formula (A-I), and pharmaceutical compositions thereof. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a parasite disease.

  公开号：

  WO2023141410A1
• 作为产物：
  描述：

  3-methylallylguaiacol 以 N-甲基吡咯烷酮 为溶剂， 以59 %的产率得到2-Methoxy-3-methyl-6-prop-2-enylphenol
  参考文献：
  名称：

  [EN] BICYCLIC QUINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS
  [FR] QUINONES BICYCLIQUES, COMPOSITIONS PHARMACEUTIQUES ET APPLICATIONS THÉRAPEUTIQUES

  摘要：

  Provided herein are bicyclic quinones,e.g., a compound of Formula (A-I), and pharmaceutical compositions thereof. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a parasite disease.

  公开号：

  WO2023141410A1

文献信息

• Towards the total synthesis of neurotrophically active tashironins: rapid construction of the tetracyclic core through a tandem oxidative dearomatization–IMDA reaction–RCM protocol
  作者：Goverdhan Mehta、Pulakesh Maity

  DOI：10.1016/j.tetlet.2007.10.052

  日期：2007.12

  An exceptionally short (three step) strategy involving tandem oxidative dearomatization, intramolecular Diels-Alder (IMDA) reaction and RCM has been devised to generate the complete carbon framework present in tashironin-type sesquiterpenoid natural products. (C) 2007 Elsevier Ltd. All rights reserved.
• [EN] BICYCLIC QUINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS<br/>[FR] QUINONES BICYCLIQUES, COMPOSITIONS PHARMACEUTIQUES ET APPLICATIONS THÉRAPEUTIQUES
  申请人：[en]IC-MEDTECH CORP.

  公开号：WO2023141410A1

  公开（公告）日：2023-07-27

  Provided herein are bicyclic quinones,e.g., a compound of Formula (A-I), and pharmaceutical compositions thereof. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a parasite disease.