α-Hydroxy-p-tolylacetaldehyd | 34025-31-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: α-Hydroxy-p-tolylacetaldehyd
• 英文别名: p-Methylmandelaldehyd；2-Hydroxy-2-(4-methylphenyl)acetaldehyde
• CAS: 34025-31-5
• 化学式: C₉H₁₀O₂
• 分子量: 150.177
• InChiKey: RAYOBZZZVWFDKL-UHFFFAOYSA-N

物化性质

• 沸点：
  258.7±28.0 °C(Predicted)
• 密度：
  1.119±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1-(4-甲基苯基)-2,2,2-三氯乙醇 在 aluminium amalgam 、 potassium hydrogencarbonate 、 异丙醇 作用下， 生成 α-Hydroxy-p-tolylacetaldehyd
  参考文献：
  名称：

  Bal'on,Ya.G.; Shul'man,M.D., Journal of Organic Chemistry USSR (English Translation), 1976, vol. 12, p. 1926 - 1931

  摘要：

  DOI：

文献信息

• Pigmented, corrosion-resistant, thermosetting coating compositions
  申请人：DeSOTO, INC.

  公开号：EP0097777A1

  公开（公告）日：1984-01-11

  A pigmented, thermosetting organic solvent solution coating composition having improved capacity to resist acid rain is disclosed in which a resinous polyepoxide, a phenoplast resin cross-linking agent for said polyepoxide (preferably a xylolol-formaldehyde condensate), a phosphoric acid catalyst, a chromium-containing pigment providing resistance to corrosion, and a clay having the capacity to fix phosphate, are combined. For package stability, the catalyst is the reaction product of ortho phosphoric acid with an aliphatic diol, there being sufficient hydroxy in said diol to provide at least 1 equivalent of hydroxy for each acid equivalent in said phosphoric acid. These coatings are applied as a prime coating which is baked to remove solvents and provide a dry film without removing the phosphoric acid contained therein. The dry primer is then overcoated with a topcoat, and the doubly coated substrate is baked to cure the first coating.

  本发明公开了一种颜料型热固性有机溶剂溶液涂料组合物，该组合物具有更强的抗酸雨能力，其中结合了树脂型聚环氧乙烷、用于所述聚环氧乙烷的酚醛树脂交联剂（最好是木酚-甲醛缩合物）、磷酸催化剂、具有抗腐蚀性的含铬颜料以及具有固定磷酸盐能力的粘土。为了保证包装的稳定性，催化剂是正磷酸与脂肪族二元醇的反应产物，二元醇中有足够的羟基，使磷酸中的每一个酸当量至少有 1 个羟基当量。这些涂料作为底层涂料使用，经过烘烤以去除溶剂并形成一层干燥的薄膜，但不会去除其中所含的磷酸。然后在干燥的底层上再涂一层面漆，并烘烤双重涂层的基底以固化第一层涂层。
• PROCESS FOR PREPARING 2-UNSUBSTITUTED IMIDAZOLES
  申请人：MITSUI PETROCHEMICAL INDUSTRIES, LTD.

  公开号：EP0252162A1

  公开（公告）日：1988-01-13

  A process for preparing 2-unsubstituted imidazoles which comprises reacting an a-hydroxycarbonyl compound with a formamide in a molar ratio of the formamide to the hydroxycarbonyl compound of 2 or less at a reaction temperature of 100 to 170°C in an atmosphere of ammonia gas. This process makes it possible to obtain 2-unsubstituted imidazoles in an extremely high yield and provides an advantage that recovering procedures involving decomposition of the formamide can be eliminated since it is not used in large excess. Removal of formic acid formed as by-product of the reaction serves to prevent corrosion of reactors and separators such as a distilling tower and yield highly pure imidazoles.

  一种制备 2-未取代咪唑的工艺，包括在氨气气氛中，在 100 至 170℃的反应温度下，使 a-羟基羰基化合物与甲酰胺反应，甲酰胺与羟基羰基化合物的摩尔比为 2 或 2 以下。通过这种工艺可以获得产率极高的 2-未取代咪唑，其优点是由于不需要过量使用甲酰胺，因此可以省去涉及甲酰胺分解的回收步骤。除去反应副产物甲酸可防止反应器和分离器（如蒸馏塔）受到腐蚀，并可获得高纯度的咪唑。
• Anticorrosive coating compositions
  申请人：DeSoto, Inc.

  公开号：EP0310687A1

  公开（公告）日：1989-04-12

  A primer coating system is disclosed that is resistant to abrasion and corrosion and includes a basecoat or first layer comprising a resinous polyepoxide, an aminoplast, phenoplast or blocked isocyanate curing agent, an epoxy-phosphate, a chromium-containing pigment and a clay that has the capacity to fix phosphate. The system may further include an overcoat or second layer comprising a resinous polyhydric alcohol, and polyisocyanate, a chromium-containing pigment and the foregoing clay, and a third layer of a finish coating preferably based on a fluorine-containing polymer.

  本发明公开了一种耐磨损和耐腐蚀的底漆涂层系统，包括底漆或第一层，由树脂多元环氧树脂、氨基树脂、酚醛树脂或封端异氰酸酯固化剂、环氧磷酸盐、含铬颜料和具有固定磷酸盐能力的粘土组成。该系统还可包括一层外涂层或第二层，由树脂多元醇、多异氰酸酯、含铬颜料和前述粘土组成，第三层最好是以含氟聚合物为基础的饰面涂层。
• TRICYCLIC KINASE INHIBITORS
  申请人：AbbVie Inc.

  公开号：EP3031324A2

  公开（公告）日：2016-06-15

  The invention provides a compound of Formula (Ie), pharmaceutically acceptable salts, prodrugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.

  本发明提供了式(Ie)化合物、药学上可接受的盐、原药、生物活性代谢物、立体异构体和异构体，其中变量在本文中定义。本发明的化合物可用于治疗免疫学和肿瘤学疾病。
• STABILISIERTE PARFÜMÖLE
  申请人：Henkel AG & Co. KGaA

  公开号：EP2536469A1

  公开（公告）日：2012-12-26