2-Amino-5-[[imino(nitroamino)methyl]amino]pentanamide | 741209-59-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-Amino-5-[[imino(nitroamino)methyl]amino]pentanamide
• 英文别名: 2-amino-5-[[amino(nitramido)methylidene]amino]pentanamide
• CAS: 741209-59-6
• 化学式: C6H14N6O3
• 分子量: 218.21
• InChiKey: BUSHIXDXHSGLAB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  165
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• PROTEASOME INHIBITORS AND METHODS OF USING THE SAME
  申请人：CEPHALON, INC.

  公开号：EP1658255A2

  公开（公告）日：2006-05-24
• [EN] PROTEASOME INHIBITORS AND METHODS OF USING THE SAME<br/>[FR] INHIBITEURS DE PROTEASOME ET METHODES LES UTILISANT
  申请人：CEPHALON INC

  公开号：WO2005016859A2

  公开（公告）日：2005-02-24

  The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly of indirectly with proteasome activity.