2-氨基-2-(2,4,6-三甲基苯基)乙酸

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 2-氨基-2-(2,4,6-三甲基苯基)乙酸
• 英文名称: 2-azaniumyl-2-(2,4,6-trimethylphenyl)acetate
• 化学式: C11H15NO2
• 分子量: 193.24
• InChiKey: ZWMOYOHAJKNZRA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  63.3
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• PEPTIDE LIGANDS OF SOMATOSTATIN RECEPTORS
  申请人：BCN Peptides, S.A.

  公开号：EP2427775A1

  公开（公告）日：2012-03-14
• CO RTI STATIN ANALOGUES FOR THE TREATMENT OF INFLAMMATORY AND/OR IMMUNE DISEASES
  申请人：BCN Peptides, S.A.

  公开号：EP3046933A1

  公开（公告）日：2016-07-27
• CORTISTATIN ANALOGUES FOR THE TREATMENT OF INFLAMMATORY AND/OR IMMUNE DISEASES
  申请人：BCN PEPTIDES, S.A.

  公开号：US20160185822A1

  公开（公告）日：2016-06-30

  The invention relates to cortistatin analogues and their uses. The compounds of the invention are peptide ligands with potential application in the diagnosis, prevention or therapy of those pathologies where receptors capable of binding to cortistatin, specific or shared with other molecules such as somatostatin and/or ghrelin (GHSR), are expressed, being in addition more stable in serum than cortistatin.
• US8946154B2
  申请人：——

  公开号：US8946154B2

  公开（公告）日：2015-02-03
• [EN] PEPTIDE LIGANDS OF SOMATOSTATIN RECEPTORS<br/>[FR] LIGANDS PEPTIDIQUES DES RÉCEPTEURS DE LA SOMATOSTATINE
  申请人：BCN PEPTIDES SA

  公开号：WO2010128098A1

  公开（公告）日：2010-11-11

  The invention relates to peptide derivatives of general formula (I), their stereoisomers, mixtures thereof and/or their pharmaceutically acceptable salts, a method of obtaining them, pharmaceutical compositions containing them and the use thereof for the treatment, prevention and/or diagnosis of those conditions, disorders and/or pathologies in which the sstrl, sstr2, sstr3, sstr4 and/or sstr5 somatostatin receptors are expressed.