rac-1,3,4-tri-tert-butyl-2,2-dichloro-1,3,2-diazagermolidine | 1167987-10-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 金属杂环化合物
• 英文名称: rac-1,3,4-tri-tert-butyl-2,2-dichloro-1,3,2-diazagermolidine
• 英文别名: (4S)-1,3,4-tritert-butyl-2,2-dichloro-1,3,2-diazagermolidine
• CAS: 1167987-10-1
• 化学式: C₁₄H₃₀Cl₂GeN₂
• 分子量: 369.902
• InChiKey: KETSGOAQROWREO-LLVKDONJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.53
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  rac-1,3,4-tri-tert-butyl-2,2-dichloro-1,3,2-diazagermolidine 在 lithium 作用下， 以 四氢呋喃 为溶剂， 以75.1%的产率得到rac-1,3,4-tri-tert-butyl-1,3-diaza-germacyclopentane-2-ylidine
  参考文献：
  名称：

  Synthesis and characterization of three new thermally stable N-heterocyclic germylenes

  摘要：

  Three new stable germylenes, rac-1,3-di-tert-butyl-4,5-dimethyl-1,3-diaza-2-germacyclopentane2-ylide (1), 1,3-di-tert-butyl-4,4-dimethyl-1,3-diaza-2-germacyclopentane-2-ylide (2), and rac-1,3,4-tritert-butyl-1,3-diaza-2-germacyclopentane-2-ylide (3) have been synthesized by the reaction of their corresponding germyl dichlorides with elemental lithium. Full synthetic procedures and characterizations are described. (c) 2009 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2008.12.042
• 作为产物：
  描述：

  N,N'-di-tert-butyl-2-tert-butylethylenediamine 、 四氯化锗 在 三乙胺 作用下， 以 正己烷 为溶剂， 以64.5%的产率得到rac-1,3,4-tri-tert-butyl-2,2-dichloro-1,3,2-diazagermolidine
  参考文献：
  名称：

  Synthesis and characterization of three new thermally stable N-heterocyclic germylenes

  摘要：

  Three new stable germylenes, rac-1,3-di-tert-butyl-4,5-dimethyl-1,3-diaza-2-germacyclopentane2-ylide (1), 1,3-di-tert-butyl-4,4-dimethyl-1,3-diaza-2-germacyclopentane-2-ylide (2), and rac-1,3,4-tritert-butyl-1,3-diaza-2-germacyclopentane-2-ylide (3) have been synthesized by the reaction of their corresponding germyl dichlorides with elemental lithium. Full synthetic procedures and characterizations are described. (c) 2009 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2008.12.042

文献信息

• Synthesis and characterization of three new thermally stable N-heterocyclic germylenes
  作者：Adam C. Tomasik、Nicholas J. Hill、Robert West

  DOI：10.1016/j.jorganchem.2008.12.042

  日期：2009.6

  Three new stable germylenes, rac-1,3-di-tert-butyl-4,5-dimethyl-1,3-diaza-2-germacyclopentane2-ylide (1), 1,3-di-tert-butyl-4,4-dimethyl-1,3-diaza-2-germacyclopentane-2-ylide (2), and rac-1,3,4-tritert-butyl-1,3-diaza-2-germacyclopentane-2-ylide (3) have been synthesized by the reaction of their corresponding germyl dichlorides with elemental lithium. Full synthetic procedures and characterizations are described. (c) 2009 Elsevier B.V. All rights reserved.