(Z)-ethyl 3-(dimethylamino)but-2-enoate | 14064-78-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (Z)-ethyl 3-(dimethylamino)but-2-enoate
• 英文别名: Ethyl β-dimethylaminocrotonate；β-Dimethylamino-crotonsaeure-aethylester；3-Dimethylamino-crotonsaeure-aethylester；Ethyl 3-(dimethylamino)-crotonate；ethyl (Z)-3-(dimethylamino)but-2-enoate
• CAS: 14064-78-9
• 化学式: C₈H₁₅NO₂
• 分子量: 157.213
• InChiKey: CTKXXMXGFDQHTI-SREVYHEPSA-N

物化性质

• 沸点：
  206.0±23.0 °C(Predicted)
• 密度：
  0.954±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  (Z)-ethyl 3-(dimethylamino)but-2-enoate 生成 2-Benzamido-5-benzoyl-4-dimethylamino-6-thioxonicotinsaeure-ethylester
  参考文献：
  名称：

  SOCHNEVA E. O.; SOLOVEVA N. P.; GRANIK V. G., XIMIYA GETEROTSIKL. SOEDIN., 1978, HO 12, 1671-1676

  摘要：

  DOI：
• 作为产物：
  描述：

  三甲基硅烷N,N-二甲基氨甲酸盐 、 乙酰乙酸乙酯 反应 4.0h， 以86%的产率得到(Z)-ethyl 3-(dimethylamino)but-2-enoate
  参考文献：
  名称：

  Reactions of silylcarbamates with ketones

  摘要：

  The reaction of N,N-dialkyl-O-trimethylsilyl carbamates with different carbonyl compounds gives enamines under mild conditions in good yields. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)01521-5

文献信息

• Alkoxide Activation of Aminoboranes towards Selective Amination
  作者：Cristina Solé、Elena Fernández

  DOI：10.1002/anie.201305098

  日期：2013.10.18

  the (inter)action: The interaction of alkoxides with the sp2 Bpin (pin=pinacol) moiety in aminoboranes forms the in situ Lewis acid–base adduct [RO−→B(OR)2N(R′)2] which enables the amino moiety to react as a strong nucleophile with several electrophiles, thus providing amino alcohols, β‐enamino esters, and β‐hydroxy amides in a direct and remarkably selective way (see scheme).

  的（相互）动作的片：醇盐与SP的相互作用2 BPIN（引脚=频哪醇）部分在氨基硼烷形式原位路易斯酸-碱加合物[RO - →B（OR）2  N（R'）2使氨基部分作为强亲核试剂与几种亲电试剂反应，从而以直接且显着选择性的方式提供氨基醇，β-烯氨基酯和β-羟基酰胺（请参见方案）。
• Substituted anthranilates
  申请人：Commonwealth Scientific and Industrial Research Organization

  公开号：US04182877A1

  公开（公告）日：1980-01-08

  Anthranilic acid derivatives exhibiting fungicidal properties and useful as synthesis intermediates have the formula: ##STR1## wherein R is selected from the group consisting of a hydrogen atom; a --COOR.sup.3 group and a --CH.sub.2 OH group; R.sup.1 and R.sup.2 are the same or different and selected from the group consisting of a hydrogen atom and alkyl and cycloalkyl groups (provided that R.sup.1 and R.sup.2 are not both hydrogen atoms), or R.sup.1 and R.sup.2, together with the nitrogen atom to which they are attached, form a non-aromatic heterocyclic ring structure; R.sup.3 is selected from the group consisting of a hydrogen atom and an alkyl group; R.sup.4 is selected from the group consisting of a hydrogen atom, a halogen atom and a hydroxyl group; R.sup.6 is selected from the group consisting of a hydrogen atom and a halogen atom; and R.sup.5 is selected from the group consisting of a hydrogen atom, a halogen atom, and nitro, thiocyano and formyl groups. A process for production of these compounds by self-condensation of a substituted aminocrotonate by phosphorous oxychloride is also disclosed.

  具有杀真菌性能并且作为合成中间体有用的邻氨基苯甲酸衍生物具有以下结构式：##STR1## 其中R选自包括氢原子；-COOR.sup.3基团和-CH.sub.2 OH基团的群体；R.sup.1和R.sup.2相同或不同，并选自包括氢原子和烷基和环烷基基团的群体（前提是R.sup.1和R.sup.2不都是氢原子），或者R.sup.1和R.sup.2连同它们附着的氮原子形成非芳香杂环环结构；R.sup.3选自包括氢原子和烷基基团的群体；R.sup.4选自包括氢原子、卤素原子和羟基的群体；R.sup.6选自包括氢原子和卤素原子的群体；R.sup.5选自包括氢原子、卤素原子和硝基、硫氰基和甲酰基的群体。还公开了通过磷氯制氯化物对取代氨基丙烯酸酯的自缩聚制备这些化合物的方法。
• Restructuring and finishing of keratin fibers
  申请人：——

  公开号：US20040261198A1

  公开（公告）日：2004-12-30

  A method for modifying keratin fibers, in particular for restructuring and finishing, by polymerizing suitable polymerizable substrates at the fiber by using a polyphenol oxidase. In addition, the invention relates to compositions comprising the substrates capable of the polymerization by means of a polyphenol oxidase and at least one polyphenol oxidase, and to the use thereof for positively influencing the fiber properties, in particular strength, porosity, elasticity, color retention and volume of the fibers.

  一种通过使用多酚氧化酶使合适的可聚合基质在纤维处聚合，从而对角蛋白纤维进行改性，特别是进行重组和整理的方法。此外，本发明还涉及包含可通过多酚氧化酶聚合的基质和至少一种多酚氧化酶的组合物，以及使用这些组合物对纤维特性，特别是纤维的强度、孔隙率、弹性、保色性和体积产生积极影响的方法。
• Synthesis of derivatives of 2-(1-ethoxycarbonyl-2-aminopropen-1-yl)-3,5-dibromohydroquinone
  作者：V. M. Lyubchanskaya、L. M. Alekseeva、V. G. Granik

  DOI：10.1007/bf00773080

  日期：1992.6
• BOEHME H.; GRAETZEL VON GRAETZ J.; MARTIN F.; MATUSCH R.; NEHNE J., LIEBIGS ANN. CHEM., 1980, NO 3, 394-402
  作者：BOEHME H.、 GRAETZEL VON GRAETZ J.、 MARTIN F.、 MATUSCH R.、 NEHNE J.

  DOI：——

  日期：——