Ethyl 4-ethyl-2,3-dioxopiperazine-1-carboxylate | 112895-04-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Ethyl 4-ethyl-2,3-dioxopiperazine-1-carboxylate
• CAS: 112895-04-2
• 化学式: C₉H₁₄N₂O₄
• 分子量: 214.22
• InChiKey: XEQWVNWHNLZPLH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  66.9
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• TRICYCLIC COMPOUND HAVING SULFINYL OR SULFONYL
  申请人：Shionogi & Co., Ltd.

  公开号：US20180186814A1

  公开（公告）日：2018-07-05

  The present invention provides a compound exhibiting a strong antimicrobial spectrum against various bacteria, including gram-negative bacteria, or a pharmaceutical composition having an antimicrobial activity carbapenem-resistant bacteria. Provided is a compound represented by formula (I), an ester thereof or a pharmaceutically acceptable salt thereof, or a hydrate thereof. (I) (in the formula, —W— is —S(═O)— or S(═O) 2 —, -T- is CR 4A R 4B — or —CR 5A —R 5B —CR 6A —R 6B —, each of R 2A and R 2B is independently a hydrogen atom, etc., or R 2A and R 2B together form a substituted or unsubstituted methylidene, etc., R 3 is a hydrogran atom, etc., R 11 is a carboxyl, etc., and each of R 7A and R 7B is independently a hydrogen atom, etc.)