2-Bromo-5,6-dimethyl-4-tetrahydropyranyloxyphenol | 176246-21-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2-Bromo-5,6-dimethyl-4-tetrahydropyranyloxyphenol
• 英文别名: 6-Bromo-2,3-dimethyl-4-(oxan-2-yloxy)phenol
• CAS: 176246-21-2
• 化学式: C₁₃H₁₇BrO₃
• 分子量: 301.18
• InChiKey: TYUFNRLGTFHSOB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  38.7
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-(三甲基硅烷基)乙氧甲基氯 、 2-Bromo-5,6-dimethyl-4-tetrahydropyranyloxyphenol 在 N,N-二异丙基乙胺 作用下， 以 二氯甲烷 为溶剂， 以92%的产率得到1-Bromo-3,4-dimethyl-5-tetrahydropyranyloxy-2-<2-(trimethylsilyl)ethoxymethoxy>benzene
  参考文献：
  名称：

  Synthesis of lurlene, the sex pheromone of the green flagellate Chlamydomonas allensworthii

  摘要：

  Lurlene [(4E,8E,12E)-14-[2'-hydroxy-3',4'-dimethyl-5'-(1 ''-beta-D-xylopyranosyloxy)phenyl]-4,8,12-trimethyltetradeca-4,8,12-trienoic acid, 1], the sex pheromone produced by the female gametes of Chlamydomonas allensworthii, was synthesized as a mixture of 1 and its (12Z)-isomer, and the mixture was bioactive.

  DOI：

  10.1016/0040-4039(96)00127-x
• 作为产物：
  描述：

  2,3-二甲基氢醌 、 alkaline earth salt of/the/ methylsulfuric acid 在 溴 、 对甲苯磺酸 作用下， 以 四氢呋喃 为溶剂， 生成 2-Bromo-5,6-dimethyl-4-tetrahydropyranyloxyphenol
  参考文献：
  名称：

  Synthesis of lurlene, the sex pheromone of the green flagellate Chlamydomonas allensworthii

  摘要：

  Lurlene [(4E,8E,12E)-14-[2'-hydroxy-3',4'-dimethyl-5'-(1 ''-beta-D-xylopyranosyloxy)phenyl]-4,8,12-trimethyltetradeca-4,8,12-trienoic acid, 1], the sex pheromone produced by the female gametes of Chlamydomonas allensworthii, was synthesized as a mixture of 1 and its (12Z)-isomer, and the mixture was bioactive.

  DOI：

  10.1016/0040-4039(96)00127-x

文献信息

• Synthesis of lurlene, the sex pheromone of the green flagellate Chlamydomonas allensworthii
  作者：Kenji Mori、Shin-ichi Takanashi

  DOI：10.1016/0040-4039(96)00127-x

  日期：1996.3

  Lurlene [(4E,8E,12E)-14-[2'-hydroxy-3',4'-dimethyl-5'-(1 ''-beta-D-xylopyranosyloxy)phenyl]-4,8,12-trimethyltetradeca-4,8,12-trienoic acid, 1], the sex pheromone produced by the female gametes of Chlamydomonas allensworthii, was synthesized as a mixture of 1 and its (12Z)-isomer, and the mixture was bioactive.