Pyridine, 2-(butoxymethyl)- | 89290-78-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: Pyridine, 2-(butoxymethyl)-
• 英文别名: 2-(butoxymethyl)pyridine
• CAS: 89290-78-8
• 化学式: C₁₀H₁₅NO
• 分子量: 165.235
• InChiKey: IWRSMXMWFHGRRC-UHFFFAOYSA-N

物化性质

• 沸点：
  222.5±15.0 °C(Predicted)
• 密度：
  0.964±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  22.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-氯甲基吡啶盐酸盐 在 Crabtree catalyst 4-(picolyloxy)-1-butene 、 氢气 、 potassium hydride 作用下， 以 甲醇 为溶剂， 25.0 ℃ 、101.33 kPa 条件下， 反应 47.5h， 生成 Pyridine, 2-(butoxymethyl)-
  参考文献：
  名称：

  Auxiliary accelerated reactions: Towards the use of catalytic chiral auxiliaries

  摘要：

  In competition experiments, the acceleration of reactivity of alkenes tethered to pyridyl groups compared with the corresponding alkenes tethered to phenyl groups in the presence of transition metals was demonstrated for two reaction types: Diels-Alder cycloaddition of enoate esters and catalytic hydrogenation of allylic and homoallylic ethers. The rate accelerations observed are of crucial importance in the development of a new concept for asymmetric catalysis: chiral auxiliaries which can function in a catalytic manner. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4020(97)00829-6

文献信息

• Wieditz, Stefan; Schaefer, Hans J., Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry, 1983, vol. 37, # 6, p. 475 - 484
  作者：Wieditz, Stefan、Schaefer, Hans J.

  DOI：——

  日期：——
• Raja, S.; Xavier, N.; Arulraj, S. J., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1988, vol. 27, # 1-12, p. 916 - 919
  作者：Raja, S.、Xavier, N.、Arulraj, S. J.

  DOI：——

  日期：——
• Auxiliary accelerated reactions: Towards the use of catalytic chiral auxiliaries
  作者：Andrew D. Westwell、Jonathan M.J. Williams

  DOI：10.1016/s0040-4020(97)00829-6

  日期：1997.9

  In competition experiments, the acceleration of reactivity of alkenes tethered to pyridyl groups compared with the corresponding alkenes tethered to phenyl groups in the presence of transition metals was demonstrated for two reaction types: Diels-Alder cycloaddition of enoate esters and catalytic hydrogenation of allylic and homoallylic ethers. The rate accelerations observed are of crucial importance in the development of a new concept for asymmetric catalysis: chiral auxiliaries which can function in a catalytic manner. (C) 1997 Elsevier Science Ltd.