N,N-diethyl-N'-(pyrid-2-ylmethyl)ethylenediamine | 104295-25-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: N,N-diethyl-N'-(pyrid-2-ylmethyl)ethylenediamine
• 英文别名: N-(2-pyridylmethyl)-N',N'-diethylethylenediamine；N--<2-diethylamino-ethyl>-amin；N-(Pyridyl-(2)-methyl)-(2-diethylamino-ethyl)-amin；1,2-Ethanediamine, N,N-diethyl-N'-(2-pyridinylmethyl)-；N',N'-diethyl-N-(pyridin-2-ylmethyl)ethane-1,2-diamine
• CAS: 104295-25-2
• 化学式: C₁₂H₂₁N₃
• mdl: MFCD05252631
• 分子量: 207.319
• InChiKey: NTYBDAULOJMFNT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  15
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.583
• 拓扑面积：
  28.2
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  copper(II) choride dihydrate 、 N,N-diethyl-N'-(pyrid-2-ylmethyl)ethylenediamine 以 甲醇 为溶剂， 以51%的产率得到
  参考文献：
  名称：

  水性和水性胶束介质中三齿3N配体单核铜（II）配合物的儿茶酚酶活性：立体电子因素对催化活性的影响

  摘要：

  摘要一系列[Cu（L）Cl2] 1–6型单核铜（II）配合物，其中L是三齿3 N配体，例如N-甲基-N'-（吡啶-2-基甲基）乙二胺（ L1），N-乙基-N'-（吡啶-2-基甲基）乙二胺（L2），N-苯基-N'-（吡啶-2-基甲基）乙二胺（L3），N，N-二甲基-N'- （吡啶-2-基甲基）乙二胺（L4），N，N-二乙基-N'-（吡啶-2-基甲基）乙二胺（L5）和N-甲基-N'-（吡啶-2-基甲基）苯- 1,2-二胺（L6）已被分离出来，并作为不同含水胶束介质中邻苯二酚氧化酶的功能模型进行了研究。2和5的X射线晶体结构包含CuN3Cl2发色团，该发色团具有基于三角形双锥体的配位几何形状。有趣的是，所有配合物都形成阳离子型[Cu（L）（DBC）（H2O）] +加合物，其中DBC2-作为单齿配体，加合物与阴离子SDS胶束强烈相互作用。加氧酶的反应速率遵循SDS> TX-100〜水> CTAB的

  DOI：

  10.1016/j.ica.2018.09.069
• 作为产物：
  描述：

  吡啶-2-甲醛 、 N,N-二乙基乙二胺 在 sodium tetrahydroborate 作用下， 以 甲醇 为溶剂， 以77%的产率得到N,N-diethyl-N'-(pyrid-2-ylmethyl)ethylenediamine
  参考文献：
  名称：

  水性和水性胶束介质中三齿3N配体单核铜（II）配合物的儿茶酚酶活性：立体电子因素对催化活性的影响

  摘要：

  摘要一系列[Cu（L）Cl2] 1–6型单核铜（II）配合物，其中L是三齿3 N配体，例如N-甲基-N'-（吡啶-2-基甲基）乙二胺（ L1），N-乙基-N'-（吡啶-2-基甲基）乙二胺（L2），N-苯基-N'-（吡啶-2-基甲基）乙二胺（L3），N，N-二甲基-N'- （吡啶-2-基甲基）乙二胺（L4），N，N-二乙基-N'-（吡啶-2-基甲基）乙二胺（L5）和N-甲基-N'-（吡啶-2-基甲基）苯- 1,2-二胺（L6）已被分离出来，并作为不同含水胶束介质中邻苯二酚氧化酶的功能模型进行了研究。2和5的X射线晶体结构包含CuN3Cl2发色团，该发色团具有基于三角形双锥体的配位几何形状。有趣的是，所有配合物都形成阳离子型[Cu（L）（DBC）（H2O）] +加合物，其中DBC2-作为单齿配体，加合物与阴离子SDS胶束强烈相互作用。加氧酶的反应速率遵循SDS> TX-100〜水> CTAB的

  DOI：

  10.1016/j.ica.2018.09.069

文献信息

• Synthesis, structure and magnetic properties of two end-on double azido bridged nickel(II) dinuclear entities incorporating N,N,N-coordinating tridentate reduced Schiff base ligands
  作者：Sumana Sarkar、Amrita Mondal、Mohamed Salah El Fallah、Joan Ribas、Deepak Chopra、Helen Stoeckli-Evans、Kajal Krishna Rajak

  DOI：10.1016/j.poly.2005.06.059

  日期：2006.1

  Complexes of the general formula [Ni2L2(mu(1.1)-N-3)(2)(N-3)(2)] have been synthesised in good yields by reacting Ni(NO3)(2)center dot 6H(2)O with L in the presence of excess of sodium azide in methanol at room temperature. Here L is N,N-bis(2-pyridylmethyl)amine (L-1) and N-(2-pyridylmethyl)-N',N'-diethylethylenediamine (L-2). The X-ray structures of both compounds reveal that the N,N,N coordinating reduced Schiff bases are ligated facially. The Ni-N-azido-Ni angle is similar to 100 degrees and the Ni center dot center dot center dot Ni separation is similar to 3.2 angstrom. The variable temperature magnetic susceptibility measurements of the two complexes show ferromagnetic behavior. (c) 2005 Elsevier Ltd. All rights reserved.
• Amido binding to ReO3+ core: Synthesis, structure and intermolecular interactions
  作者：Amrita Mondal、Sumana Sarkar、Deepak Chopra、Kajal Krishna Rajak

  DOI：10.1016/j.ica.2006.01.017

  日期：2006.4

  The light green coloured complexes of general formula [(ReO)-O-V(L)CI(OH2)]Cl have been synthesised in good yields by reacting [RcvOCl(3)(AsPh3)21 with HL in dichloromethane in dinitrogen atmosphere. Here, L- is the deprotonated form of N',N'-bis(2-pyridylmethyl)amine (HL1); N-(2-pyridylmethyl)-N',N'-dimethylethylenediamine (HL2) and N-(2-pyridylmethyl)-N',N-diethylethylenediamine (HL3). Single crystal X-ray structure determination of [(ReO)-O-V(L-1)Cl(OH2)Cl confirms the amido binding of ReO3+ species. In the solid state of [(ReO)-O-V(L-1)Cl(OH2)]Cl, the coordinated and counter chloride ions are engaged in Re-Cl... H-C(ring), Cl...H-C(ring) and Re(OH2)...Cl hydrogen bonding and forming of a supramolecular network in the solid state. The subunit of the supramolecular network consists of one eight-membered and two nine-membered hydrogen bonded rings. The average diameters of eight-membered and nine-membered rings are similar to 3.70 and similar to 5.26 angstrom, respectively. (c) 2006 Elsevier B.V. All rights reserved.
• Mono, di and polynuclear Cu(II)–azido complexes incorporating N,N,N reduced schiff base: syntheses, structure and magnetic behavior
  作者：Sumana Sarkar、Amrita Mondal、Joan Ribas、M.G.B. Drew、Kausikisankar Pramanik、Kajal Krishna Rajak

  DOI：10.1016/j.ica.2004.09.055

  日期：2005.2

  Three kinds of copper(II) azide complexes have been synthesised in excellent yields by reacting Cu(ClO4)(2) . 6H(2)O with N,N-bis(2-pyridylmethyl)amine (L-1); N-(2-pyridylmethyl)-N',N'-dimethylethylenediamine (L-2); and N-(2-pyridylmethyl)-N',N'-diethylethylenediamine (L-3), respectively, in the presence of slight excess of sodium azide. They are the monomeric Cu(L-1)(N-3)(ClO4) (1), the end-to-end diazido-bridged Cu-2(L-2)(2)(mu-1,3-N-3)(2)(ClO4)(2) (2) and the single azido-bridged (mu-1,3-) 1D chain [Cu(L-3)(mu-1,3-N-3)](n)(ClO4)(n) (3). The crystal and molecular structures of these complexes have been solved. The variable temperature magnetic moments of type 2 and type 3 complexes were studied. Temperature dependent susceptibility for 2 was fitted using the Bleaney-Bowers expression which led to the parameters J = -3.43 cm(-1) and R = 1 X 10(-5). The magnetic data for 3 were fitted to Baker's expression for S = 1/2 and the parameters obtained were J = 1.6 cm(-1) and R = 3.2 x 10(-4). Crystal data are as follows. Cu(L-1)(N-3)(ClO4): Chemical formula, C12H13ClN6O4Cu; crystal system, monoclinic; space group, P2(1)/c; a = 8.788(12), b = 13.045(15), c = 14.213(15) Angstrom; beta = 102.960(10)degrees; Z = 4. Cu(L-2)(mu-N-3)(ClO4): Chemical formula. C10H17ClN6O4Cu: crystal system, monoclinic; space group, P2(1)/c; a = 10.790(12), b = 8.568(9), c = 16.651(17) Angstrom; beta = 102.360(10)degrees; Z = 4. [Cu(L-3)(mu-N-3)](ClO4): Chemical formula, C12H21ClN6O4Cu; crystal system, monoclinic; space group, P2(1)/c; a = 12.331(14), b = 7.804(9), c = 18.64(2) Angstrom; beta = 103.405(10)degrees; Z = 4. (C) 2004 Elsevier B.V. All rights reserved.
• Catecholase activity of mononuclear copper(II) complexes of tridentate 3N ligands in aqueous and aqueous micellar media: Influence of stereoelectronic factors on catalytic activity
  作者：Natarajan Anitha、Natarajan Saravanan、Tamilarasan Ajaykamal、Eringathodi Suresh、Mallayan Palaniandavar

  DOI：10.1016/j.ica.2018.09.069

  日期：2019.1

  Abstract A series of mononuclear copper(II) complexes of the type [Cu(L)Cl2] 1–6, where L is a tridentate 3 N ligand such as N-methyl-N′-(pyrid-2-ylmethyl)ethylenediamine (L1), N-ethyl-N′-(pyrid-2-ylmethyl)ethylenediamine (L2), N-phenyl-N′-(pyrid-2-ylmethyl)ethylenediamine (L3), N,N-dimethyl-N′-(pyrid-2-ylmethyl)ethylenediamine (L4), N,N-diethyl-N′-(pyrid-2-ylmethyl)-ethylenediamine (L5) and N-met

  摘要一系列[Cu（L）Cl2] 1–6型单核铜（II）配合物，其中L是三齿3 N配体，例如N-甲基-N'-（吡啶-2-基甲基）乙二胺（ L1），N-乙基-N'-（吡啶-2-基甲基）乙二胺（L2），N-苯基-N'-（吡啶-2-基甲基）乙二胺（L3），N，N-二甲基-N'- （吡啶-2-基甲基）乙二胺（L4），N，N-二乙基-N'-（吡啶-2-基甲基）乙二胺（L5）和N-甲基-N'-（吡啶-2-基甲基）苯- 1,2-二胺（L6）已被分离出来，并作为不同含水胶束介质中邻苯二酚氧化酶的功能模型进行了研究。2和5的X射线晶体结构包含CuN3Cl2发色团，该发色团具有基于三角形双锥体的配位几何形状。有趣的是，所有配合物都形成阳离子型[Cu（L）（DBC）（H2O）] +加合物，其中DBC2-作为单齿配体，加合物与阴离子SDS胶束强烈相互作用。加氧酶的反应速率遵循SDS> TX-100〜水> CTAB的