trans-5,8-Diphenyl-6-dodecene | 118438-13-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: trans-5,8-Diphenyl-6-dodecene
• 英文别名: [(E)-8-phenyldodec-6-en-5-yl]benzene
• CAS: 118438-13-4；118438-14-5；120853-58-9；133447-89-9；133447-90-2；133470-53-8
• 化学式: C₂₄H₃₂
• 分子量: 320.518
• InChiKey: ZRBPHDCTBUJMQL-FMQUCBEESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.7
• 重原子数：
  24
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  (E,E)-(η6:η6-1,4-diphenyl-1,3-butadiene)bis(tricarbonylchromium) 、 正溴丁烷 以2%的产率得到
  参考文献：
  名称：

  RIEKE, R. D.;DARUWALA, K. P.;FORKNER, M. W., J. ORG. CHEM., 54,(1989) N, C. 21-24

  摘要：

  DOI：

文献信息

• Reduction of (E,E)-(.eta.6:.eta.6-1,4-diphenyl-1,3-butadiene)bis(tricarbonylchromium), followed by reaction with electrophiles. A regioselective method for the preparation of substituted 1,4-diphenylbutenes
  作者：Reuben D. Rieke、Khushroo P. Daruwala、Matthew W. Forkner

  DOI：10.1021/jo00262a011

  日期：1989.1
• Chemistry of substituted (2-butene-1,4-diyl)magnesium: a facile approach to complex carbocycles, functionalized ketones and alcohols, and silicon-containing heterocycles
  作者：Reuben D. Rieke、Heping Xiong

  DOI：10.1021/jo00009a034

  日期：1991.4

  Highly reactive magnesium reacts with a wide variety of substituted 1,3-dienes to give the corresponding substituted (2-butene-1,4-diyl)magnesium complexes. Reactions of symmetrical (2-butene-1,4-diyl)magnesium with alpha,omega-alkylene dihalides form three-, four-, five-, and six-membered carbocycles. Significantly, the cyclizations are always stereospecific and completely regioselective. Depending on the initial 1,3-diene and specific electrophiles, uncyclized products can be obtained. Stepwise reactions of (2,3-dimethyl-2-butene-1,4-diyl)magnesium with two different electrophiles afford polyfunctionalized ketones with the generation of a quaternary center. Formal 1,2-additions can be effected in this manner. Substituted five- and six-membered cyclic ketones can also be synthesized in one step by this approach. Treatment of unsymmetrical (2-butene-1,4-diyl)magnesium complexes with triorganosilyl chlorides followed by cyclohexanone results in additions across a terminal double bond with high regioselectivity. Silicon-containing heterocycles or spiro compounds can be readily synthesized by using the bis-Grignard reagents.
• RIEKE, R. D.;DARUWALA, K. P.;FORKNER, M. W., J. ORG. CHEM., 54,(1989) N, C. 21-24
  作者：RIEKE, R. D.、DARUWALA, K. P.、FORKNER, M. W.

  DOI：——

  日期：——