4-bromo-2,3',5'-trifluoro-1,1'-biphenyl | 1096100-65-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-bromo-2,3',5'-trifluoro-1,1'-biphenyl
• 英文别名: 1-(4-bromo-2-fluorophenyl)-3,5-difluorobenzene
• CAS: 1096100-65-0
• 化学式: C₁₂H₆BrF₃
• 分子量: 287.079
• InChiKey: APYRMPZYNOLYEP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-bromo-2,3',5'-trifluoro-1,1'-biphenyl 在 正丁基锂 、 magnesium 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 反应 9.0h， 生成
  参考文献：
  名称：

  COMPOUND HAVING BRANCHED ALKYL OR BRANCHED ALKENYL, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL ELEMENT

  摘要：

  公开号：

  EP2586764B1
• 作为产物：
  描述：

  3,5-difluorophenylboric acid 、 1-溴-3-氟-4-碘苯 在 bis(triphenylphosphine)palladium(II) dichloride 、 四丁基溴化铵 、 potassium carbonate 、 三苯基膦 作用下， 以 乙醇 、 甲苯 为溶剂， 反应 6.0h， 以77%的产率得到4-bromo-2,3',5'-trifluoro-1,1'-biphenyl
  参考文献：
  名称：

  COMPOUND HAVING BRANCHED ALKYL OR BRANCHED ALKENYL, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL ELEMENT

  摘要：

  公开号：

  EP2586764B1

文献信息

• LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：GOTO Shuichi

  公开号：US20110180756A1

  公开（公告）日：2011-07-28

  The subject is to provide a liquid crystal composition that satisfies at least one of characteristics such as a high maximum temperature of a nematic phase, a low minimum temperature of a nematic phase, a small viscosity, a suitable optical anisotropy, a large dielectric anisotropy, a large specific resistance, a high stability to ultraviolet light, a high stability to heat and a large elastic constant, or that is suitably balanced regarding at least two of the characteristics. The subject is to provide an AM device that has a short response time, a large voltage holding ratio, a large contrast ratio, a long service life and so forth. The invention provides a liquid crystal composition that has a nematic phase and includes a specific four-ring compound having a high maximum temperature and a large dielectric anisotropy as a first component and a specific compound having a small dielectric anisotropy as a second component, and also provides a liquid crystal display device containing this composition. The invention further provides the compound of the first component.

  本主题是提供一种液晶组合物，满足至少以下特性之一：向列相的最高温度高，向列相的最低温度低，粘度小，适当的光学各向异性，大的介电各向异性，大的特定电阻，对紫外光稳定性高，对热稳定性高以及大的弹性常数，或者在至少两个特性中适当平衡。本主题是提供一种具有短响应时间、大电压保持比、大对比度、长寿命等特性的AM装置。该发明提供了一种具有向列相的液晶组合物，包括具有高最高温度和大介电各向异性的特定四环化合物作为第一组分，以及具有小介电各向异性的特定化合物作为第二组分，并且提供了含有该组合物的液晶显示装置。该发明还提供了第一组分的化合物。
• Optically isotropic liquid crystal medium and optical device
  申请人：JNC Corporation

  公开号：US08609208B2

  公开（公告）日：2013-12-17

  A liquid crystal medium having an optically isotropic liquid crystal phase is described, which has stability to heat, light and so on, a broad temperature range of liquid crystal phase, a large optical anisotropy and a large dielectric anisotropy. A liquid crystal composition is described, which includes an achiral component T and a chiral dopant and exhibits an optically isotropic liquid crystal phase. The achiral component T contains, as its first component, at least one compound selected from compounds represented by formula (1), wherein R1 is C1-10 alkyl, the rings A1 to A6 are 1,4-phenylene, Z1 to Z7 are single bonds, Y1 and Y2 are fluorine; X1 is halogen, and i, j, k, m, n, p and q are independently 0 or 1.

  描述了一种具有光学各向同性液晶相的液晶介质，具有耐热、耐光等稳定性，液晶相具有宽广的温度范围，大的光学各向异性和大的介电各向异性。描述了一种液晶组分，包括一个非手性组分T和一个手性掺杂剂，并展现了光学各向同性液晶相。非手性组分T包含至少一种由式（1）所表示的化合物中的第一组分，其中R1是C1-10烷基，环A1到A6是1,4-苯撑基，Z1到Z7是单键，Y1和Y2是氟；X1是卤素，而i，j，k，m，n，p和q是独立的0或1。
• OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE
  申请人：JNC CORPORATION

  公开号：US20130114009A1

  公开（公告）日：2013-05-09

  A liquid crystal medium having an optically isotropic liquid crystal phase is described, which has stability to heat, light and so on, a broad temperature range of liquid crystal phase, a large optical anisotropy and a large dielectric anisotropy. A liquid crystal composition is described, which includes an achiral component T and a chiral dopant and exhibits an optically isotropic liquid crystal phase. The achiral component T contains, as its first component, at least one compound selected from compounds represented by formula (1), wherein R 1 is C 1-10 alkyl, the rings A 1 to A 6 are 1,4-phenylene, Z 1 to Z 7 are single bonds, Y 1 and Y 2 are fluorine; X 1 is halogen, and i, j, k, m, n, p and q are independently 0 or 1.

  描述了一种具有光学各向同性液晶相的液晶介质，具有对热、光等的稳定性，液晶相的广泛温度范围，大的光学各向异性和大的介电各向异性。描述了一种液晶组分，其中包括一个无手性组分T和一个手性掺杂剂，并展现出光学各向同性液晶相。无手性组分T包含至少一种由式（1）表示的化合物作为其第一组分，其中R1是C1-10烷基，环A1到A6是1,4-苯撑基，Z1到Z7是单键，Y1和Y2是氟；X1是卤素，i、j、k、m、n、p和q独立地为0或1。
• ORTHOESTER DERIVATIVE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：Masukawa Tokifumi

  公开号：US20140021407A1

  公开（公告）日：2014-01-23

  The invention is to provide a liquid crystal compound having a large dielectric anisotropy, a high voltage holding ratio and stability to heat, light and so forth, maintaining a nematic phase in a wide temperature range, having a suitable optical anisotropy and an excellent compatibility with other liquid crystal compounds, particularly, to provide a liquid crystal compound having a large dielectric anisotropy. The invention provides compound (1): In the formula, for example, R 1 is alkyl having 1 to 20 carbons; ring A 1 , ring A 2 , ring A 3 , ring A 4 , ring A 5 and ring A 6 are independently 1,4-cyclohexylene or 1,4-phenylene; Z 1 , Z 2 , Z 3 , Z 4 , Z 5 , Z 6 and Z 7 are independently a single bond, —(CH 2 ) 2 —, —COO—, —OCO—, —CF 2 O—, —OCF 2 — or —CH═CH—; X 1 is fluorine, —CF 3 or —OCF 3 ; and Y 1 and Y 2 are independently hydrogen or fluorine.

  本发明旨在提供一种具有大的介电各向异性、高电压保持比和对热、光等的稳定性，在广泛的温度范围内保持向列相，具有适当的光学各向异性和与其他液晶化合物良好的相容性，特别是提供一种具有大的介电各向异性的液晶化合物。本发明提供化合物(1)：其中，在公式中，例如，R1是具有1至20个碳的烷基；环A1、环A2、环A3、环A4、环A5和环A6独立地是1,4-环己亚甲基或1,4-苯亚甲基；Z1、Z2、Z3、Z4、Z5、Z6和Z7独立地是单键，-(CH2)2-，-COO-，-OCO-，-CF2O-，-OCF2-或-CH═CH-；X1是氟、-CF3或-OCF3；而Y1和Y2独立地是氢或氟。
• ORTHO ESTER DERIVATIVE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT
  申请人：JNC Corporation

  公开号：EP2690103A1

  公开（公告）日：2014-01-29

  The invention is to provide a liquid crystal compound having a large dielectric anisotropy, a high voltage holding ratio and stability to heat, light and so forth, maintaining a nematic phase in a wide temperature range, having a suitable optical anisotropy and an excellent compatibility with other liquid crystal compounds, particularly, to provide a liquid crystal compound having a large dielectric anisotropy. The invention provides compound (1): In the formula, for example, R1 is alkyl and having 1 to 20 carbons; ring A1, ring A2, ring A3, ring A4, ring A5 and ring A6 are independently 1,4-cyclohexylene or 1,4-phenylene; Z1, Z2, Z3, Z4, Z5, Z6 and Z7 are independently a single bond, - (CH2) 2-, -COO-, -OCO-, CF2O-, -OCF2- or -CH=CH-; X1 is fluorine, -CF3 or -OCF3; and Y1 and Y2 are independently hydrogen or fluorine.

  本发明旨在提供一种液晶化合物，它具有较大的介电各向异性、较高的电压保持比和对热、光等的稳定性，在较宽的温度范围内保持向列相，具有合适的光学各向异性，与其他液晶化合物具有良好的相容性，特别是提供一种具有较大介电各向异性的液晶化合物。本发明提供了化合物（1）： 例如，在式中，R1 是烷基，具有 1 至 20 个碳原子；环 A1、环 A2、环 A3、环 A4、环 A5 和环 A6 独立地是 1，4-环己烯或 1，4-亚苯基；Z1、Z2、Z3、Z4、Z5、Z6 和 Z7 独立地为单键、- (CH2)2-、-COO-、-OCO-、CF2O-、-OCF2- 或 -CH=CH-；X1 为氟、-CF3 或 -OCF3；以及 Y1 和 Y2 独立地为氢或氟。