1-Oxy-pyridine-2,6-dicarbonyl dichloride | 160714-39-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 1-Oxy-pyridine-2,6-dicarbonyl dichloride
• 英文别名: 1-Oxidopyridin-1-ium-2,6-dicarbonyl chloride；1-oxidopyridin-1-ium-2,6-dicarbonyl chloride
• CAS: 160714-39-6
• 化学式: C₇H₃Cl₂NO₃
• 分子量: 220.012
• InChiKey: PQYGPFZBSVTDGO-UHFFFAOYSA-N

物化性质

• 沸点：
  432.1±25.0 °C(Predicted)
• 密度：
  1.59±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  59.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-Oxy-pyridine-2,6-dicarbonyl dichloride 、 2’-氨基苯甲酰苯胺 在 吡啶 作用下， 以 二氯甲烷 为溶剂， 生成
  参考文献：
  名称：

  Oligoanthranilamides. Non-Peptide Subunits That Show Formation of Specific Secondary Structure

  摘要：

  A family of novel oligomers based on the anthranilamide nucleus has been prepared and shown to form well-defined secondary structural features. H-1 NMR and X-ray crystallographic techniques have demonstrated that intramolecular hydrogen bonds play a key role in stabilizing both linear sheet and helical conformational forms.

  DOI：

  10.1021/ja9539857
• 作为产物：
  描述：

  吡啶-2,6-二羧酸 n-氧化物 在 氯化亚砜 作用下， 反应 2.0h， 生成 1-Oxy-pyridine-2,6-dicarbonyl dichloride
  参考文献：
  名称：

  Self-assembly of aromatic sulfonamide–amide hybridized molecules: formation of 2D layers and 3D microporous networks in the solid state

  摘要：

  Three sulfonamide-amide hybridized molecules and one cyclic analogue were synthesized and their assembling behaviors in the solid state were investigated by X-ray crystallography. The results showed that the hybridized molecules could be not only induced to take up helical secondary structures by a network of intramolecular hydrogen bonds, but also utilized as useful building blocks for assembling into 1D zigzag chains and superhelices, 2D layers and further 3D networks. Moreover, it was found that the multiple C-(HO)-O-. . .=S hydrogen bonds played an important role in the assembling processes. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2005.12.058

文献信息

• Oligoanthranilamides. Non-Peptide Subunits That Show Formation of Specific Secondary Structure
  作者：Yoshitomo Hamuro、Steven J. Geib、Andrew D. Hamilton

  DOI：10.1021/ja9539857

  日期：1996.1.1

  A family of novel oligomers based on the anthranilamide nucleus has been prepared and shown to form well-defined secondary structural features. H-1 NMR and X-ray crystallographic techniques have demonstrated that intramolecular hydrogen bonds play a key role in stabilizing both linear sheet and helical conformational forms.
• Self-assembly of aromatic sulfonamide–amide hybridized molecules: formation of 2D layers and 3D microporous networks in the solid state
  作者：Zhi-Qiang Hu、Chuan-Feng Chen

  DOI：10.1016/j.tet.2005.12.058

  日期：2006.4

  Three sulfonamide-amide hybridized molecules and one cyclic analogue were synthesized and their assembling behaviors in the solid state were investigated by X-ray crystallography. The results showed that the hybridized molecules could be not only induced to take up helical secondary structures by a network of intramolecular hydrogen bonds, but also utilized as useful building blocks for assembling into 1D zigzag chains and superhelices, 2D layers and further 3D networks. Moreover, it was found that the multiple C-(HO)-O-. . .=S hydrogen bonds played an important role in the assembling processes. (c) 2006 Elsevier Ltd. All rights reserved.