octadeca-9,12,15-trienal | 26537-71-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: octadeca-9,12,15-trienal
• 英文别名: 9,12,15-Octadecatrienal；(9E,12E,15E)-octadeca-9,12,15-trienal
• CAS: 26537-71-3
• 化学式: C₁₈H₃₀O
• 分子量: 262.436
• InChiKey: TUCMDDWTBVMRTP-IUQGRGSQSA-N

物化性质

• 沸点：
  368.1±21.0 °C(Predicted)
• 密度：
  0.863±0.06 g/cm3(Predicted)
• 保留指数：
  2109;2061

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  19
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.61
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2912190090

文献信息

• [EN] EXTERNAL PREPARATION FOR SKIN<br/>[FR] PREPARATION EXTERNE POUR LA PEAU
  申请人：SHOWA DENKO KK

  公开号：WO2005094777A1

  公开（公告）日：2005-10-13

  The present invention provides an external preparation for skin, which comprises a multi-branched polysaccharide derivative with multi-branched polysaccharide skeleton consisting of saccharides as constituent units, wherein at least one of hydroxyl (OH) groups in the multi-branched polysaccharide skeleton is substituted by OR (wherein R represents a hydrogen atom, a hydrocarbon having 1 to 30 carbon groups or a hydrocarbon having 1 to 30 carbon groups which has hetero atom), which can give moisture and turgor to the skin, and cosmetics containing the external preparation.

  本发明提供了一种用于皮肤的外用制剂，其包括一种多支链多糖衍生物，该多支链多糖骨架由糖组成的多支链多糖骨架组成，其中多支链多糖骨架中的至少一个羟基（OH）被取代为OR（其中R代表氢原子、具有1至30个碳基团的碳氢化合物或具有1至30个碳基团的碳氢化合物，其具有杂原子），可以为皮肤提供水分和弹性，并且含有该外用制剂的化妆品。
• NOVEL ESTERS OF N-ACYL DERIVATIVES OF AMINO ACIDS AND DIOLS, METHOD FOR PREPARING SAME, AND USE THEREOF IN COSMETICS AND AS A DRUG
  申请人：SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC

  公开号：US20140288144A1

  公开（公告）日：2014-09-25

  A compound of formula (I): R′—O-A-O—R″″, in which R′ and R″ are a hydrogen atom or a monovalent radical of formula (IIa), or a monovalent radical of formula (IIb), it being understood that at least one of the radicals R′ or R″ is not a hydrogen atom and that, when none of the radicals R′ and R″ is a hydrogen atom, R′ and R″ are identical, and in which A is a divalent radical of formula (III): —CH(X1)-[C(X2)(X3)]p-CH(X4) in which X1, X2, X3 and X4 are identical or different and are either a hydrogen atom or a methyl radical or an ethyl radical, and p is an integer greater than or equal to 1 and less than or equal to 6. Also the method for preparing the compound of formula (I) and to the use thereof in cosmetics and as a drug.

  一种化合物的化学式（I）：R′—O-A-O—R″″，其中R′和R″是氢原子或化学式（IIa）的一价基团，或化学式（IIb）的一价基团，至少其中一个基团R′或R″不是氢原子，并且当R′和R″均不是氢原子时，它们相同，其中A是化学式（III）的二价基团：—CH(X1)-[C(X2)(X3)]p-CH(X4)，其中X1、X2、X3和X4相同或不同，可以是氢原子、甲基基团或乙基基团，p是大于或等于1且小于或等于6的整数。还涉及制备化学式（I）的化合物的方法以及在化妆品和药物中的用途。
• [EN] TOPICAL SLIMMING PREPARATION AND A COSMETIC CONTAINING A CARNITINE DERIVATIVE<br/>[FR] PRÉPARATION EXTERNE POUR L'AMINCISSEMENT DE LA PEAU ET PRODUIT COSMÉTIQUE CONTENANT CETTE PRÉPARATION
  申请人：SHOWA DENKO KK

  公开号：WO2005115326A1

  公开（公告）日：2005-12-08

  The invention provides a slimming skin external preparation and a cosmetic that contain a carnitine derivative having excellent skin affinity and percutaneous absorption properties and capable of enhancing the fat metabolism, and that can treat, reduce or prevent the obesity by functioning as a lipolytic agent to enhance the fat metabolism of general or local subcutaneous fat tissues. The slimming skin external preparation contains a particular carnitine derivative such as a cylcarnitines and alcohol carnitine esters and preferably other slimming and skin-care ingredients.

  本发明提供了一种减肥皮肤外用制剂和化妆品，其中包含一种肉碱衍生物，具有优异的皮肤亲和性和经皮吸收性能，能够增强脂肪代谢，并且能够作为脂肪分解剂，促进一般或局部皮下脂肪组织的脂肪代谢，从而治疗、减少或预防肥胖。该减肥皮肤外用制剂包含特定的肉碱衍生物，如环肉碱和醇肉碱酯，并且最好还包含其他减肥和护肤成分。
• NOVEL ESTERS OF N-ACYLATED DERIVATIVES OF AMINO ACIDS AND ISOSORBIDE, METHOD FOR PREPARING SAME, AND USE THEREOF IN COSMETICS AND AS DRUG
  申请人：Benattar Andre

  公开号：US20140135373A1

  公开（公告）日：2014-05-15

  Compound with formula (I), wherein R′ and R″ represent a hydrogen atom, a monovalent radical with formula (IIa), or a monovalent radical with formula (IIb), it being understood that at least one of the R′ or R″ radicals does not represent a hydrogen atom and that when the R′ and R″ radicals do not represent a hydrogen atom, R′ and R″ are identical; method for preparing and using in cosmetics and as a drug.

  公式（I）的化合物，其中R′和R″表示氢原子，具有公式（IIa）的一价基团，或具有公式（IIb）的一价基团，其中至少一个R′或R″基团不表示氢原子，当R′和R″基团均不表示氢原子时，R′和R″相同；制备方法，并用于化妆品和药物。
• [EN] HYDROXYCITRIC ACID DERIVATIVES AND SKIN EXTERNAL PREPARATIONS CONTAINING THE SAME<br/>[FR] DERIVES D'ACIDE HYDROXYCITRIQUE ET PREPARATIONS EXTERNES POUR LA PEAU LES CONTENANT
  申请人：SHOWA DENKO KK

  公开号：WO2006033476A1

  公开（公告）日：2006-03-30

  Hydroxycitric acid derivatives and salts thereof are provided which are useful as active ingredients of skin external preparations and cosmetics. Also provided are processes for production of the hydroxycitric acid derivatives, and skin external preparations and cosmetics containing the hydroxycitric acid derivatives. Specific hydroxycitric acid derivatives or salts thereof are produced wherein at least one of the hydroxyl groups of hydroxycitric acid, or least one of the hydroxyl groups and at least one carboxyl group of hydroxycitric acid are modified to linkage moieties breakable by biological enzyme reaction. The hydroxycitric acid derivatives or salts thereof are added in skin external preparations and cosmetics.

  提供了羟基柠檬酸衍生物及其盐，可用作皮肤外用制剂和化妆品的活性成分。还提供了生产羟基柠檬酸衍生物的方法，以及含有羟基柠檬酸衍生物的皮肤外用制剂和化妆品。生产特定羟基柠檬酸衍生物或其盐，其中羟基柠檬酸的至少一个羟基或至少一个羟基和至少一个羧基被修饰为可被生物酶反应断裂的连接基团。将羟基柠檬酸衍生物或其盐添加到皮肤外用制剂和化妆品中。