6-Aminooxyhexyl 2-dodecylsulfanylcarbothioylsulfanyl-2-methylpropanoate | 1204502-22-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 6-Aminooxyhexyl 2-dodecylsulfanylcarbothioylsulfanyl-2-methylpropanoate
• 英文别名: 6-aminooxyhexyl 2-dodecylsulfanylcarbothioylsulfanyl-2-methylpropanoate
• CAS: 1204502-22-6
• 化学式: C₂₃H₄₅NO₃S₃
• 分子量: 479.813
• InChiKey: BSDMZUSTNGAFDO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.8
• 重原子数：
  30
• 可旋转键数：
  23
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  144
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  6-Aminooxyhexyl 2-dodecylsulfanylcarbothioylsulfanyl-2-methylpropanoate 、 2-[2-[2-(2-Dodecylsulfanylcarbothioylsulfanyl-2-methylpropanoyl)oxyethoxy]ethoxy]ethyl 4-formylbenzoate 在 三氟乙酸 作用下， 以 氘代氯仿 为溶剂， 生成
  参考文献：
  名称：

  Dynamic Covalent Diblock Copolymers Prepared from RAFT Generated Aldehyde and Alkoxyamine End-Functionalized Polymers

  摘要：

  Aldehyde- or alkoxyamine-containing trithiocarbonate chain transfer agents were prepared and used to mediate the synthesis of a series of polymers end-functionlized with either aldehyde or alkoxyamines functions, utilizing reversible addition-fragmentation polymerization techniques. Aldehyde end-functionalized polymers were shown to link through reversible oxime bond formation with alkoxyamine end-funtionalized polymers forming diblock copolymers. The dynamic nature of the oxime bond linking these polymer blocks together was demonstrated through a simple exchange reaction with a small molecule alkoxyamine. A diblock copolymer prepared from the self-assembly of an aldehyde end-functionalized polyisoprenc with an alkoxyamine end-functionalized polystyrene was shown to undergo further hierarchical self-assembly into micellar aggregates in DMF. It was shown that the addition of an excess of a small molecule alkoxyamine triggered the disassembly of these micelles.

  DOI：

  10.1021/ma902291a
• 作为产物：
  描述：

  6-溴正己醇 在 4-二甲氨基吡啶 、 1,8-二氮杂双环[5.4.0]十一碳-7-烯 、 盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺 、 三氟乙酸 作用下， 以 二氯甲烷 为溶剂， 反应 0.5h， 生成 6-Aminooxyhexyl 2-dodecylsulfanylcarbothioylsulfanyl-2-methylpropanoate
  参考文献：
  名称：

  Dynamic Covalent Diblock Copolymers Prepared from RAFT Generated Aldehyde and Alkoxyamine End-Functionalized Polymers

  摘要：

  Aldehyde- or alkoxyamine-containing trithiocarbonate chain transfer agents were prepared and used to mediate the synthesis of a series of polymers end-functionlized with either aldehyde or alkoxyamines functions, utilizing reversible addition-fragmentation polymerization techniques. Aldehyde end-functionalized polymers were shown to link through reversible oxime bond formation with alkoxyamine end-funtionalized polymers forming diblock copolymers. The dynamic nature of the oxime bond linking these polymer blocks together was demonstrated through a simple exchange reaction with a small molecule alkoxyamine. A diblock copolymer prepared from the self-assembly of an aldehyde end-functionalized polyisoprenc with an alkoxyamine end-functionalized polystyrene was shown to undergo further hierarchical self-assembly into micellar aggregates in DMF. It was shown that the addition of an excess of a small molecule alkoxyamine triggered the disassembly of these micelles.

  DOI：

  10.1021/ma902291a

文献信息

• Dynamic Covalent Diblock Copolymers Prepared from RAFT Generated Aldehyde and Alkoxyamine End-Functionalized Polymers
  作者：Alexander W. Jackson、David A. Fulton

  DOI：10.1021/ma902291a

  日期：2010.1.26

  Aldehyde- or alkoxyamine-containing trithiocarbonate chain transfer agents were prepared and used to mediate the synthesis of a series of polymers end-functionlized with either aldehyde or alkoxyamines functions, utilizing reversible addition-fragmentation polymerization techniques. Aldehyde end-functionalized polymers were shown to link through reversible oxime bond formation with alkoxyamine end-funtionalized polymers forming diblock copolymers. The dynamic nature of the oxime bond linking these polymer blocks together was demonstrated through a simple exchange reaction with a small molecule alkoxyamine. A diblock copolymer prepared from the self-assembly of an aldehyde end-functionalized polyisoprenc with an alkoxyamine end-functionalized polystyrene was shown to undergo further hierarchical self-assembly into micellar aggregates in DMF. It was shown that the addition of an excess of a small molecule alkoxyamine triggered the disassembly of these micelles.